Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026)
Bicycle Therapeutics' (BCYC) quarterly Change in Cash came in at -$50.0 million in Q2 2026, up 30.13% YoY from -$38.4 million in Q2 2025, and up 27.2% on a QoQ basis from -$68.6 million in Q1 2026.
Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026) Analysis & Trends
Bicycle Therapeutics (BCYC) has 9 years of Change in Cash data on file, last reported at -$50.0 million in Q2 2026.
- Quarterly Change in Cash rose 30.13% year-over-year to -$50.0 million in Q2 2026, while the trailing twelve-month figure through Jun 2026 was -$211.9 million (up 11.68% YoY) and the FY2025 annual result came in at -$251.4 million, down 171.18% from the prior year.
- Change in Cash advanced to -$50.0 million in Q2 2026, from -$68.6 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $504.4 million in Q2 2024 to a low of -$86.5 million in Q1 2025.
- A 5-year average of $4.0 million and a median of -$40.0 million in 2022 frame the typical range for Change in Cash.
- Annual changes were most pronounced in 2022 — Change in Cash tumbled 1319.67% — and 2023, when it soared 2154.88%.
- Tracing BCYC's Change in Cash over 5 years: stood at -$22.3 million in 2022, then slumped by 104.63% to -$45.7 million in 2023, then jumped by 75.16% to -$11.3 million in 2024, then plunged by 77.72% to -$20.2 million in 2025, then slumped by 147.9% to -$50.0 million in 2026.
- The last three Change in Cash figures came in at -$50.0 million (Q2 2026), -$68.6 million (Q1 2026), and -$20.2 million (Q4 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 374.50 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 427.25 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -1.97 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 225.59 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -2.94 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Bicycle Therapeutics | 272.28 Mn | 272.28 Mn | - | -49.97 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -49.97 Mn |
| Mar 31, 2026 | -68.64 Mn |
| Dec 31, 2025 | -20.16 Mn |
| Sep 30, 2025 | -73.13 Mn |
| Jun 30, 2025 | -71.52 Mn |
| Mar 31, 2025 | -86.55 Mn |
| Dec 31, 2024 | -11.34 Mn |
| Sep 30, 2024 | -70.50 Mn |
| Jun 30, 2024 | 504.37 Mn |
| Mar 31, 2024 | -69.43 Mn |
| Dec 31, 2023 | -45.66 Mn |
| Sep 30, 2023 | 232.20 Mn |
| Jun 30, 2023 | 46.62 Mn |
| Mar 31, 2023 | -45.34 Mn |
| Dec 31, 2022 | -22.32 Mn |
| Sep 30, 2022 | -11.30 Mn |
| Jun 30, 2022 | -34.60 Mn |
| Mar 31, 2022 | -31.31 Mn |
| Dec 31, 2021 | 179.16 Mn |
| Sep 30, 2021 | 60.79 Mn |