Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Change in Cash of -$68.6 million for Q1 2026, up 20.7% on a YoY basis from -$56.9 million in Q1 2025, and down 240.51% quarter-over-quarter from -$20.2 million in Q4 2025.

Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Change in Cash for 9 years, with the latest figure at -$68.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Cash rose 20.7% year-over-year to -$68.6 million; the trailing twelve-month figure through Mar 2026 stood at -$233.4 million (down 169.48% YoY), and the FY2025 full-year result was -$251.4 million, down 171.18% from the prior year.
  • Change in Cash for Q1 2026 stood at -$68.6 million, down from -$20.2 million in the prior quarter.
  • The five-year high for Change in Cash was $504.4 million in Q2 2024, with the low at -$86.5 million in Q1 2025.
  • Historically, Change in Cash has averaged $7.1 million across 5 years, with a median of -$34.6 million in 2022.
  • Annual changes were most pronounced in 2022 — Change in Cash tumbled 1319.67% — and 2023, when it soared 2154.88%.
  • Bicycle Therapeutics' Change in Cash stood at -$22.3 million in 2022, then slumped by 104.63% to -$45.7 million in 2023, then jumped by 75.16% to -$11.3 million in 2024, then plunged by 77.72% to -$20.2 million in 2025, then tumbled by 240.51% to -$68.6 million in 2026.
  • The last three Change in Cash figures came in at -$68.6 million (Q1 2026), -$20.2 million (Q4 2025), and -$73.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - -68.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -68.64 Mn
Dec 31, 2025 -20.16 Mn
Sep 30, 2025 -73.13 Mn
Jun 30, 2025 -71.52 Mn
Mar 31, 2025 -86.55 Mn
Dec 31, 2024 -11.34 Mn
Sep 30, 2024 -70.50 Mn
Jun 30, 2024 504.37 Mn
Mar 31, 2024 -69.43 Mn
Dec 31, 2023 -45.66 Mn
Sep 30, 2023 232.20 Mn
Jun 30, 2023 46.62 Mn
Mar 31, 2023 -45.34 Mn
Dec 31, 2022 -22.32 Mn
Sep 30, 2022 -11.30 Mn
Jun 30, 2022 -34.60 Mn
Mar 31, 2022 -31.31 Mn
Dec 31, 2021 179.16 Mn
Sep 30, 2021 60.79 Mn
Jun 30, 2021 2.84 Mn