Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026)
Bicycle Therapeutics (BCYC) posted Change in Cash of -$68.6 million for Q1 2026, down 240.51% on a QoQ basis from -$20.2 million in Q4 2025, and up 20.7% year-over-year from -$56.9 million in Q1 2025.
Bicycle Therapeutics (BCYC) Change in Cash (2018 - 2026) Analysis & Trends
Bicycle Therapeutics' Change in Cash history runs 9 years deep, the most recent figure standing at -$68.6 million for Q1 2026.
- Quarterly Change in Cash rose 20.7% year-over-year to -$68.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$233.4 million (down 169.48% YoY) and the FY2025 annual result came in at -$251.4 million, down 171.18% from the prior year.
- Change in Cash was -$68.6 million for Q1 2026 at Bicycle Therapeutics, down from -$20.2 million in the prior quarter.
- Across five years, Change in Cash topped out at $504.4 million in Q2 2024 and bottomed at -$86.5 million in Q1 2025.
- A 5-year average of $7.1 million and a median of -$34.6 million in 2022 frame the typical range for Change in Cash.
- Annual changes were most pronounced in 2022 — Change in Cash slumped 1319.67% — and 2023, when it soared 2154.88%.
- Bicycle Therapeutics' Change in Cash stood at -$22.3 million in 2022, then plunged by 104.63% to -$45.7 million in 2023, then soared by 75.16% to -$11.3 million in 2024, then slumped by 77.72% to -$20.2 million in 2025, then sank by 240.51% to -$68.6 million in 2026.
- Business Quant data shows BCYC's Change in Cash at -$68.6 million in Q1 2026, -$20.2 million in Q4 2025, and -$73.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -22.03 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 243.78 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.34 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 417.10 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -153.10 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 57.19 Mn |
| 10 | Bicycle Therapeutics | 289.88 Mn | 289.88 Mn | - | -68.64 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -68.64 Mn |
| Dec 31, 2025 | -20.16 Mn |
| Sep 30, 2025 | -73.13 Mn |
| Jun 30, 2025 | -71.52 Mn |
| Mar 31, 2025 | -86.55 Mn |
| Dec 31, 2024 | -11.34 Mn |
| Sep 30, 2024 | -70.50 Mn |
| Jun 30, 2024 | 504.37 Mn |
| Mar 31, 2024 | -69.43 Mn |
| Dec 31, 2023 | -45.66 Mn |
| Sep 30, 2023 | 232.20 Mn |
| Jun 30, 2023 | 46.62 Mn |
| Mar 31, 2023 | -45.34 Mn |
| Dec 31, 2022 | -22.32 Mn |
| Sep 30, 2022 | -11.30 Mn |
| Jun 30, 2022 | -34.60 Mn |
| Mar 31, 2022 | -31.31 Mn |
| Dec 31, 2021 | 179.16 Mn |
| Sep 30, 2021 | 60.79 Mn |
| Jun 30, 2021 | 2.84 Mn |