Axsome Therapeutics (AXSM) Return on Sales [ROS] (2022 - 2026)
Axsome Therapeutics (AXSM) posted Return on Sales [ROS] of -4.26% for Q3 2026, up 22.70 percentage points from -26.97% a year earlier and up 18.47 percentage points from the prior quarter.
Axsome Therapeutics (AXSM) Return on Sales [ROS] (2022 - 2026) Analysis & Trends
For the trailing twelve months through Sep 30, 2026, Return on Sales [ROS] at Axsome Therapeutics was -17.45%, up 20.39 percentage points year-over-year; for FY2025, it came in at -26.12%, up 46.62 percentage points from FY2024.
- Annual Return on Sales [ROS] has increased for three consecutive years, with a three-year change of +333.21 percentage points (FY2022 to FY2025).
- In prior years, Axsome Therapeutics' Return on Sales [ROS] was -72.74% in FY2024 (+12.93 pp), -85.67% in FY2023 (+273.66 pp) and -359.33% in FY2022.
- The Q3 2026 figure stands as the highest quarterly Return on Sales [ROS] in data going back to Q2 2022.
- On a year-over-year basis, Return on Sales [ROS] has increased in each of the last ten quarters, with an average year-over-year change of +37.81 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Return on Sales [ROS] in the past five years was Q2 2023, with a gain of 304.92 percentage points; the weakest was Q1 2024, with a drop of 82.96 percentage points.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -22.73% (Q2 2026), -33.14% (Q1 2026) and -13.75% (Q4 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Axsome Therapeutics | 7.41 Bn | 6.15 Bn | 241.89 Mn | -4.26% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -4.26% |
| Jun 30, 2026 | -22.73% |
| Mar 31, 2026 | -33.14% |
| Dec 31, 2025 | -13.75% |
| Sep 30, 2025 | -26.97% |
| Jun 30, 2025 | -24.47% |
| Mar 31, 2025 | -46.91% |
| Dec 31, 2024 | -61.14% |
| Sep 30, 2024 | -59.78% |
| Jun 30, 2024 | -89.54% |
| Mar 31, 2024 | -89.70% |
| Dec 31, 2023 | -137.39% |
| Sep 30, 2023 | -107.49% |
| Jun 30, 2023 | -139.31% |
| Mar 31, 2023 | -6.74% |
| Dec 31, 2022 | -245.86% |
| Sep 30, 2022 | -251.76% |
| Jun 30, 2022 | -444.23% |
Axsome Therapeutics Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();