Axsome Therapeutics (AXSM) Return on Equity [ROE] (2016 - 2026)
Axsome Therapeutics (AXSM) recorded Return on Equity [ROE] of -278.02% in Q2 2026, up 112.95 percentage points from -390.97% a year earlier but down 14.44 percentage points from the prior quarter.
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Analysis
Axsome Therapeutics (AXSM) Return on Equity [ROE] (2016 - 2026) Analysis & Trends
For FY2025, Axsome Therapeutics reported Return on Equity [ROE] of -252.11%, down 20.48 percentage points from FY2024.
- Annual Return on Equity [ROE] has a five-year change of -182.58 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -231.63% in FY2024 (-72.42 pp), -159.21% in FY2023 (+139.76 pp), -298.97% in FY2022 (-97.45 pp) and -201.51% in FY2021 (-131.97 pp).
- Quarterly Return on Equity [ROE] has ranged from -1002.97% in Q2 2022 to -73.62% in Q3 2023 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has increased for four consecutive quarters, with an average year-over-year change of -59.50 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 908.52 percentage points in Q2 2023, against a drop of 868.90 percentage points in Q2 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -263.58% (Q1 2026), -226.11% (Q4 2025) and -312.65% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Axsome Therapeutics | 9.64 Bn | 8.37 Bn | 204.81 Mn | -278.02% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -278.02% |
| Mar 31, 2026 | -263.58% |
| Dec 31, 2025 | -226.11% |
| Sep 30, 2025 | -312.65% |
| Jun 30, 2025 | -390.97% |
| Mar 31, 2025 | -504.94% |
| Dec 31, 2024 | -383.18% |
| Sep 30, 2024 | -317.69% |
| Jun 30, 2024 | -249.92% |
| Mar 31, 2024 | -176.91% |
| Dec 31, 2023 | -103.90% |
| Sep 30, 2023 | -73.62% |
| Jun 30, 2023 | -94.45% |
| Mar 31, 2023 | -143.42% |
| Dec 31, 2022 | -140.22% |
| Sep 30, 2022 | -185.29% |
| Jun 30, 2022 | -1,002.97% |
| Mar 31, 2022 | -928.32% |
| Dec 31, 2021 | -446.98% |
| Sep 30, 2021 | -220.13% |
API Access
Axsome Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();