Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026)
Axsome Therapeutics (AXSM) recorded Return on Capital Employed [ROCE] of -67.15% in Q2 2026, up 15.76 percentage points from -82.91% a year earlier but down 1.20 percentage points from the prior quarter.
Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026) Analysis & Trends
For FY2025, Axsome Therapeutics reported Return on Capital Employed [ROCE] of -66.62%, up 13.94 percentage points from FY2024.
- Annual Return on Capital Employed [ROCE] has a five-year change of -11.51 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Capital Employed [ROCE] came in at -80.56% in FY2024 (-8.34 pp), -72.22% in FY2023 (+86.80 pp), -159.02% in FY2022 (-49.52 pp) and -109.49% in FY2021 (-54.39 pp).
- Quarterly Return on Capital Employed [ROCE] has ranged from -212.43% in Q1 2022 to -39.36% in Q3 2023 over the past five years.
- On a year-over-year basis, Return on Capital Employed [ROCE] has increased for five consecutive quarters, with an average year-over-year change of -2.06 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Capital Employed [ROCE] in the last five years was a gain of 155.48 percentage points in Q1 2023, against a drop of 151.40 percentage points in Q1 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -65.96% (Q1 2026), -55.46% (Q4 2025) and -72.20% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 46.74% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 17.83% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 17.92% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 6.28% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 19.32% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 9.54% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 16.66% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 11.86% |
| 10 | Axsome Therapeutics | 9.37 Bn | 8.10 Bn | 204.81 Mn | -67.15% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -67.15% |
| Mar 31, 2026 | -65.96% |
| Dec 31, 2025 | -55.46% |
| Sep 30, 2025 | -72.20% |
| Jun 30, 2025 | -82.91% |
| Mar 31, 2025 | -79.80% |
| Dec 31, 2024 | -83.78% |
| Sep 30, 2024 | -85.38% |
| Jun 30, 2024 | -84.82% |
| Mar 31, 2024 | -69.21% |
| Dec 31, 2023 | -50.87% |
| Sep 30, 2023 | -39.36% |
| Jun 30, 2023 | -45.08% |
| Mar 31, 2023 | -56.95% |
| Dec 31, 2022 | -75.34% |
| Sep 30, 2022 | -76.45% |
| Jun 30, 2022 | -155.98% |
| Mar 31, 2022 | -212.43% |
| Dec 31, 2021 | -157.60% |
| Sep 30, 2021 | -113.89% |
Axsome Therapeutics Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();