Axsome Therapeutics AXSM
NASDAQ AXSM
$149.11 +8.14 (+5.77%)
As of: Nov 11, 2026 · 3:59 PM EST

Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026)

Updated

Axsome Therapeutics (AXSM) recorded Return on Capital Employed [ROCE] of -53.11% in Q3 2026, up 19.09 percentage points from -72.20% a year earlier and up 14.05 percentage points from the prior quarter.

Analysis

Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026) Analysis & Trends

For FY2025, Axsome Therapeutics reported Return on Capital Employed [ROCE] of -66.62%, up 13.94 percentage points from FY2024.

  • Annual Return on Capital Employed [ROCE] has a five-year change of -11.51 percentage points (FY2020 to FY2025).
  • Across earlier years, Return on Capital Employed [ROCE] came in at -80.56% in FY2024 (-8.34 pp), -72.22% in FY2023 (+86.80 pp), -159.02% in FY2022 (-49.52 pp) and -109.49% in FY2021 (-54.39 pp).
  • The Q3 2026 figure is the highest quarterly Return on Capital Employed [ROCE] since Q4 2023.
  • On a year-over-year basis, Return on Capital Employed [ROCE] has increased for six consecutive quarters, with an average year-over-year change of +6.08 percentage points over the last eight quarters.
  • Peak year-over-year performance for Return on Capital Employed [ROCE] in the last five years was a gain of 155.48 percentage points in Q1 2023, against a drop of 151.40 percentage points in Q1 2022 at the low end.
  • Per Business Quant, the preceding three quarters came in at -67.15% (Q2 2026), -65.96% (Q1 2026) and -55.46% (Q4 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 35.41%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 17.52%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn 21.60%
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 4.65%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 9.91%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 17.37%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn -6.15%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 11.32%
10 Axsome Therapeutics 7.41 Bn 6.15 Bn 241.89 Mn -53.11%
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 -53.11%
Jun 30, 2026 -67.15%
Mar 31, 2026 -65.96%
Dec 31, 2025 -55.46%
Sep 30, 2025 -72.20%
Jun 30, 2025 -82.91%
Mar 31, 2025 -79.80%
Dec 31, 2024 -83.78%
Sep 30, 2024 -85.38%
Jun 30, 2024 -84.82%
Mar 31, 2024 -69.21%
Dec 31, 2023 -50.87%
Sep 30, 2023 -39.36%
Jun 30, 2023 -45.08%
Mar 31, 2023 -56.95%
Dec 31, 2022 -75.34%
Sep 30, 2022 -76.45%
Jun 30, 2022 -155.98%
Mar 31, 2022 -212.43%
Dec 31, 2021 -157.60%
API Access

Axsome Therapeutics Return on Capital Employed [ROCE] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY