Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026)
Axsome Therapeutics (AXSM) recorded Return on Capital Employed [ROCE] of -53.11% in Q3 2026, up 19.09 percentage points from -72.20% a year earlier and up 14.05 percentage points from the prior quarter.
Axsome Therapeutics (AXSM) Return on Capital Employed [ROCE] (2016 - 2026) Analysis & Trends
For FY2025, Axsome Therapeutics reported Return on Capital Employed [ROCE] of -66.62%, up 13.94 percentage points from FY2024.
- Annual Return on Capital Employed [ROCE] has a five-year change of -11.51 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Capital Employed [ROCE] came in at -80.56% in FY2024 (-8.34 pp), -72.22% in FY2023 (+86.80 pp), -159.02% in FY2022 (-49.52 pp) and -109.49% in FY2021 (-54.39 pp).
- The Q3 2026 figure is the highest quarterly Return on Capital Employed [ROCE] since Q4 2023.
- On a year-over-year basis, Return on Capital Employed [ROCE] has increased for six consecutive quarters, with an average year-over-year change of +6.08 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Capital Employed [ROCE] in the last five years was a gain of 155.48 percentage points in Q1 2023, against a drop of 151.40 percentage points in Q1 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -67.15% (Q2 2026), -65.96% (Q1 2026) and -55.46% (Q4 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 35.41% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 17.52% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 21.60% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 4.65% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 9.91% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 17.37% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -6.15% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 11.32% |
| 10 | Axsome Therapeutics | 7.41 Bn | 6.15 Bn | 241.89 Mn | -53.11% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -53.11% |
| Jun 30, 2026 | -67.15% |
| Mar 31, 2026 | -65.96% |
| Dec 31, 2025 | -55.46% |
| Sep 30, 2025 | -72.20% |
| Jun 30, 2025 | -82.91% |
| Mar 31, 2025 | -79.80% |
| Dec 31, 2024 | -83.78% |
| Sep 30, 2024 | -85.38% |
| Jun 30, 2024 | -84.82% |
| Mar 31, 2024 | -69.21% |
| Dec 31, 2023 | -50.87% |
| Sep 30, 2023 | -39.36% |
| Jun 30, 2023 | -45.08% |
| Mar 31, 2023 | -56.95% |
| Dec 31, 2022 | -75.34% |
| Sep 30, 2022 | -76.45% |
| Jun 30, 2022 | -155.98% |
| Mar 31, 2022 | -212.43% |
| Dec 31, 2021 | -157.60% |
Axsome Therapeutics Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();