Avalo Therapeutics (AVTX) Operating Income (2014 - 2026)

Avalo Therapeutics' (AVTX) quarterly Operating Income came in at -$20.9 million in Q1 2026, down 42.48% YoY from -$36.3 million in Q1 2025, and down 5.87% on a QoQ basis from -$19.7 million in Q4 2025.

Avalo Therapeutics (AVTX) Operating Income (2014 - 2026) Analysis & Trends

Avalo Therapeutics (AVTX) has 13 years of Operating Income data on file, last reported at -$20.9 million in Q1 2026.

  • Quarterly Operating Income fell 42.48% year-over-year to -$20.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$79.2 million (down 57.01% YoY) and the FY2025 annual result came in at -$72.9 million, down 6.44% from the prior year.
  • Operating Income eased to -$20.9 million in Q1 2026, from -$19.7 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $4.1 million in Q3 2022 to a low of -$32.8 million in Q1 2024.
  • A 5-year average of -$13.4 million and a median of -$12.9 million in 2024 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2022 — Operating Income soared 124.87% — and 2024, when it slumped 272.69%.
  • Tracing AVTX's Operating Income over 5 years: stood at -$8.9 million in 2022, then advanced by 13.52% to -$7.7 million in 2023, then tumbled by 73.82% to -$13.3 million in 2024, then tumbled by 48.31% to -$19.7 million in 2025, then decreased by 5.87% to -$20.9 million in 2026.
  • The last three Operating Income figures came in at -$20.9 million (Q1 2026), -$19.7 million (Q4 2025), and -$19.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Avalo Therapeutics 854.16 Mn 453.89 Mn - -31.52 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -31.52 Mn
Mar 31, 2026 -20.90 Mn
Dec 31, 2025 -19.74 Mn
Sep 30, 2025 -19.20 Mn
Jun 30, 2025 -19.32 Mn
Mar 31, 2025 -14.67 Mn
Dec 31, 2024 -13.31 Mn
Sep 30, 2024 -12.86 Mn
Jun 30, 2024 -9.58 Mn
Mar 31, 2024 -32.77 Mn
Dec 31, 2023 -7.66 Mn
Sep 30, 2023 -3.75 Mn
Jun 30, 2023 -7.15 Mn
Mar 31, 2023 -8.79 Mn
Dec 31, 2022 -8.86 Mn
Sep 30, 2022 4.10 Mn
Jun 30, 2022 -11.83 Mn
Mar 31, 2022 -20.85 Mn
Dec 31, 2021 -17.96 Mn
Sep 30, 2021 -16.46 Mn