Avalo Therapeutics (AVTX) Net Margin (2016 - 2026)
Avalo Therapeutics (AVTX) posted Net Margin of -23323.73% for Q4 2025, down 4918.00 percentage points from -18405.73% a year earlier.
Powered by 
Analysis
Avalo Therapeutics (AVTX) Net Margin (2016 - 2026) Analysis & Trends
For FY2025, Avalo Therapeutics' Net Margin came in at -132711.86%, down 124746.10 percentage points from FY2024.
- Annual Net Margin has declined for three consecutive years, with a five-year change of -131763.96 percentage points (FY2020 to FY2025).
- In prior years, Avalo Therapeutics' Net Margin was -7965.76% in FY2024 (-6326.26 pp), -1639.50% in FY2023 (-1408.72 pp), -230.78% in FY2022 (+1332.32 pp) and -1563.10% in FY2021 (-615.19 pp).
- The Q4 2025 figure stands as the lowest quarterly Net Margin in data going back to Q3 2016.
- The strongest year-over-year quarter for Net Margin in the past five years was Q3 2024, with a gain of 11467.06 percentage points; the weakest was Q4 2024, with a drop of 16975.26 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 30.88% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 21.86% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 21.27% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | -8.04% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 22.65% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 16.30% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 23.62% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -134.51% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | -1.65% |
| 10 | Avalo Therapeutics | 533.82 Mn | -158.40 Mn | - | -1,316.84% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,316.84% |
| Mar 31, 2026 | -2,444.58% |
| Dec 31, 2025 | -23,323.73% |
| Jun 30, 2025 | -1,892.89% |
| Mar 31, 2025 | -1,145.38% |
| Dec 31, 2024 | -18,405.73% |
| Sep 30, 2024 | 9,251.81% |
| Dec 31, 2023 | -1,430.47% |
| Sep 30, 2023 | -2,215.25% |
| Jun 30, 2023 | -1,274.18% |
| Mar 31, 2023 | -2,095.79% |
| Dec 31, 2022 | -1,095.09% |
| Sep 30, 2022 | 21.35% |
| Jun 30, 2022 | -1,257.21% |
| Mar 31, 2022 | -1,879.88% |
| Dec 31, 2021 | -8,765.30% |
| Sep 30, 2021 | -1,288.52% |
| Jun 30, 2021 | -509.84% |
| Mar 31, 2021 | -6,486.26% |
| Dec 31, 2020 | -1,044.96% |
API Access
Avalo Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=AVTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "AVTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=AVTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();