Avalo Therapeutics (AVTX) Net Margin (2016 - 2025)
Avalo Therapeutics (AVTX) posted Net Margin of 23254.24% for Q4 2025, down 26.34% on a QoQ basis from 18405.73% in Q4 2024, and down 484851.0% year-over-year from N/an in Q4 2024.
Avalo Therapeutics (AVTX) Net Margin (2016 - 2025) Analysis & Trends
Avalo Therapeutics' Net Margin history runs 9 years deep, the most recent figure standing at 23254.24% for Q4 2025.
- Quarterly Net Margin fell 484851.0% year-over-year to 23254.24% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 15651.8% (down 768604.0% YoY) and the FY2025 annual result came in at 132642.37%, down 12467661.0% from the prior year.
- Net Margin was 23254.24% for Q4 2025 at Avalo Therapeutics, down from 18405.73% in the prior quarter.
- Across five years, Net Margin topped out at 9251.81% in Q3 2024 and bottomed at 23254.24% in Q4 2025.
- A 4-year average of 3588.02% and a median of 1274.18% in 2023 frame the typical range for Net Margin.
- Peak annual rise in Net Margin reached 1146706 bps in 2024, while the deepest fall reached 1697526 bps in 2024.
- Avalo Therapeutics' Net Margin stood at 29.68% in 2021, then tumbled by 4720 bps to 1430.47% in 2023, then plunged by 1187 bps to 18405.73% in 2024, then decreased by 26 bps to 23254.24% in 2025.
- Business Quant data shows AVTX's Net Margin at 23254.24% in Q4 2025, 18405.73% in Q4 2024, and 9251.81% in Q3 2024.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Avalo Therapeutics | 1.04 Mn | 1.04 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -23,254.24% |
| Dec 31, 2024 | -18,405.73% |
| Sep 30, 2024 | 9,251.81% |
| Dec 31, 2023 | -1,430.47% |
| Sep 30, 2023 | -2,215.25% |
| Jun 30, 2023 | -1,274.18% |
| Mar 31, 2023 | -2,095.79% |
| Dec 31, 2021 | -29.68% |
| Sep 30, 2021 | 5.63% |
| Jun 30, 2021 | 2.06% |
| Mar 31, 2021 | -22.41% |
| Dec 31, 2020 | 33.33% |
| Sep 30, 2020 | -17.82% |
| Jun 30, 2020 | -34.01% |
| Mar 31, 2020 | 37.69% |
| Dec 31, 2019 | 183.28% |
| Sep 30, 2019 | -49.33% |
| Jun 30, 2019 | -262.78% |
| Mar 31, 2019 | -88.95% |
| Dec 31, 2018 | 12.36% |