Avalo Therapeutics (AVTX) FCF Margin (2016 - 2025)

Avalo Therapeutics (AVTX) posted FCF Margin of 24216.95% for Q4 2025, down 209.07% on a QoQ basis from 7835.42% in Q4 2024, and down 1638153.0% year-over-year from N/an in Q4 2024.

Avalo Therapeutics (AVTX) FCF Margin (2016 - 2025) Analysis & Trends

Avalo Therapeutics' FCF Margin history runs 10 years deep, the most recent figure standing at 24216.95% for Q4 2025.

  • Quarterly FCF Margin fell 1638153.0% year-over-year to 24216.95% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 10300.0% (up 82381.0% YoY) and the FY2025 annual result came in at 87288.14%, down 7616433.0% from the prior year.
  • FCF Margin was 24216.95% for Q4 2025 at Avalo Therapeutics, down from 7835.42% in the prior quarter.
  • Across five years, FCF Margin topped out at 38.68% in Q3 2022 and bottomed at 24216.95% in Q4 2025.
  • A 5-year average of 4004.93% and a median of 1714.77% in 2023 frame the typical range for FCF Margin.
  • Annual changes were most pronounced in 2022 — FCF Margin soared 690081 bps — and 2025, when it slumped 1638153 bps.
  • Avalo Therapeutics' FCF Margin stood at 7351.14% in 2021, then jumped by 94 bps to 450.33% in 2022, then retreated by 8 bps to 484.41% in 2023, then tumbled by 1518 bps to 7835.42% in 2024, then tumbled by 209 bps to 24216.95% in 2025.
  • Business Quant data shows AVTX's FCF Margin at 24216.95% in Q4 2025, 7835.42% in Q4 2024, and 4629.32% in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.45%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 43.35%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.53%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Avalo Therapeutics 1.04 Mn 1.04 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -24,216.95%
Dec 31, 2024 -7,835.42%
Sep 30, 2024 -4,629.32%
Dec 31, 2023 -484.41%
Sep 30, 2023 -2,896.61%
Jun 30, 2023 -1,714.77%
Mar 31, 2023 -2,149.47%
Dec 31, 2022 -450.33%
Sep 30, 2022 38.68%
Jun 30, 2022 -1,212.58%
Mar 31, 2022 -1,369.74%
Dec 31, 2021 -7,351.14%
Sep 30, 2021 -1,353.26%
Jun 30, 2021 -571.89%
Mar 31, 2021 -3,876.74%
Dec 31, 2020 -964.46%
Sep 30, 2020 -1,068.41%
Jun 30, 2020 -639.39%
Mar 31, 2020 -208.39%
Dec 31, 2019 -42.04%