Avalo Therapeutics (AVTX) EBT Margin (2016 - 2025)

Avalo Therapeutics' (AVTX) quarterly EBT Margin came in at 23033.9% in Q4 2025, down 468754.0% YoY from N/an in Q4 2024, and down 25.55% on a QoQ basis from 18346.35% in Q4 2024.

Avalo Therapeutics (AVTX) EBT Margin (2016 - 2025) Analysis & Trends

Avalo Therapeutics (AVTX) has 10 years of EBT Margin data on file, last reported at 23033.9% in Q4 2025.

  • Quarterly EBT Margin fell 468754.0% year-over-year to 23033.9% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 15618.8% (down 767889.0% YoY) and the FY2025 annual result came in at 132362.71%, down 12442280.0% from the prior year.
  • EBT Margin fell to 23033.9% in Q4 2025, from 18346.35% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 9246.18% in Q3 2024 to a low of 23033.9% in Q4 2025.
  • A 5-year average of 4024.64% and a median of 1432.05% in 2023 frame the typical range for EBT Margin.
  • The widest YoY moves for EBT Margin: up 1145805 bps in 2024, down 1691431 bps in 2024.
  • Tracing AVTX's EBT Margin over 5 years: stood at 8742.92% in 2021, then surged by 87 bps to 1094.2% in 2022, then tumbled by 31 bps to 1432.05% in 2023, then sank by 1181 bps to 18346.35% in 2024, then retreated by 26 bps to 23033.9% in 2025.
  • The last three EBT Margin figures came in at 23033.9% (Q4 2025), 18346.35% (Q4 2024), and 9246.18% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Avalo Therapeutics 854.16 Mn 453.89 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -23,033.90%
Dec 31, 2024 -18,346.35%
Sep 30, 2024 9,246.18%
Dec 31, 2023 -1,432.05%
Sep 30, 2023 -2,211.86%
Jun 30, 2023 -1,273.09%
Mar 31, 2023 -2,094.11%
Dec 31, 2022 -1,094.20%
Sep 30, 2022 21.39%
Jun 30, 2022 -1,256.73%
Mar 31, 2022 -1,879.11%
Dec 31, 2021 -8,742.92%
Sep 30, 2021 -1,293.56%
Jun 30, 2021 -517.82%
Mar 31, 2021 -6,461.52%
Dec 31, 2020 -1,090.71%
Sep 30, 2020 -1,193.34%
Jun 30, 2020 -992.53%
Mar 31, 2020 -882.79%
Dec 31, 2019 -141.58%