Avalo Therapeutics (AVTX) EBT Margin (2016 - 2025)

Avalo Therapeutics posted quarterly EBT Margin of 23033.9% for Q4 2025, down 468754.0% year-on-year from N/an in Q4 2024, and down 25.55% on a QoQ basis from 18346.35% in Q4 2024.

Avalo Therapeutics (AVTX) has 10 years of EBT Margin data on file, last reported at 23033.9% in Q4 2025.

  • For the quarter ending Q4 2025, EBT Margin fell 468754.0% year-over-year to 23033.9%; the trailing twelve-month figure through Dec 2025 stood at 15618.8% (down 767889.0% YoY), and the FY2025 full-year result was 132362.71%, down 12442280.0% from the prior year.
  • EBT Margin for Q4 2025 stood at 23033.9%, down from 18346.35% in the prior quarter.
  • Across five years, EBT Margin topped out at 9246.18% in Q3 2024 and bottomed at 23033.9% in Q4 2025.
  • The 5-year median for EBT Margin is 1432.05% (2023), against an average of 4024.64%.
  • Peak annual rise in EBT Margin reached 1145805 bps in 2024, while the deepest fall reached 1691431 bps in 2024.
  • A 5-year view of EBT Margin shows it stood at 8742.92% in 2021, then soared by 87 bps to 1094.2% in 2022, then slumped by 31 bps to 1432.05% in 2023, then plunged by 1181 bps to 18346.35% in 2024, then decreased by 26 bps to 23033.9% in 2025.
  • The last three EBT Margin figures came in at 23033.9% (Q4 2025), 18346.35% (Q4 2024), and 9246.18% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.40%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 41.95%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 23.05%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 18.99%
10 Avalo Therapeutics 317.29 Mn 317.29 Mn - -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -23,033.90%
Dec 31, 2024 -18,346.35%
Sep 30, 2024 9,246.18%
Dec 31, 2023 -1,432.05%
Sep 30, 2023 -2,211.86%
Jun 30, 2023 -1,273.09%
Mar 31, 2023 -2,094.11%
Dec 31, 2022 -1,094.20%
Sep 30, 2022 21.39%
Jun 30, 2022 -1,256.73%
Mar 31, 2022 -1,879.11%
Dec 31, 2021 -8,742.92%
Sep 30, 2021 -1,293.56%
Jun 30, 2021 -517.82%
Mar 31, 2021 -6,461.52%
Dec 31, 2020 -1,090.71%
Sep 30, 2020 -1,193.34%
Jun 30, 2020 -992.53%
Mar 31, 2020 -882.79%
Dec 31, 2019 -974.36%
Sep 30, 2019 -127.60%
Jun 30, 2019 -178.94%
Mar 31, 2019 -195.30%
Dec 31, 2018 14.60%
Sep 30, 2018 -602.51%
Jun 30, 2018 -125.20%
Mar 31, 2018 -86.09%
Dec 31, 2017 -227.90%
Sep 30, 2017 87.67%
Jun 30, 2017 -1,139.74%
Mar 31, 2017 -510.31%
Dec 31, 2016 -900.39%
Sep 30, 2016 -1,918.75%
Jun 30, 2016 -555.74%