Avalo Therapeutics (AVTX) EBITDA (2014 - 2026)

Avalo Therapeutics posted quarterly EBITDA of -$19.7 million for Q1 2026, down 49.85% year-on-year from -$39.3 million in Q1 2025, and down 43.9% on a QoQ basis from -$13.7 million in Q4 2025.

Avalo Therapeutics (AVTX) has 13 years of EBITDA data on file, last reported at -$19.7 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 49.85% year-over-year to -$19.7 million; the trailing twelve-month figure through Mar 2026 stood at -$84.7 million (down 216.07% YoY), and the FY2025 full-year result was -$78.2 million, down 122.58% from the prior year.
  • EBITDA for Q1 2026 stood at -$19.7 million, down from -$13.7 million in the prior quarter.
  • Across five years, EBITDA topped out at $98.5 million in Q2 2024 and bottomed at -$121.3 million in Q1 2024.
  • The 5-year median for EBITDA is -$13.0 million (2022), against an average of -$12.0 million.
  • Peak annual rise in EBITDA reached 1301.79% in 2024, while the deepest fall reached 1118.38% in 2024.
  • A 5-year view of EBITDA shows it stood at -$8.9 million in 2022, then climbed by 13.52% to -$7.7 million in 2023, then tumbled by 361.47% to -$35.3 million in 2024, then jumped by 61.25% to -$13.7 million in 2025, then plunged by 43.9% to -$19.7 million in 2026.
  • The last three EBITDA figures came in at -$19.7 million (Q1 2026), -$13.7 million (Q4 2025), and -$30.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Avalo Therapeutics 317.29 Mn 317.29 Mn - -19.70 Mn

Historic Data

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DateValue
Mar 31, 2026 -19.70 Mn
Dec 31, 2025 -13.69 Mn
Sep 30, 2025 -30.55 Mn
Jun 30, 2025 -20.80 Mn
Mar 31, 2025 -13.15 Mn
Dec 31, 2024 -35.34 Mn
Sep 30, 2024 23.04 Mn
Jun 30, 2024 98.46 Mn
Mar 31, 2024 -121.29 Mn
Dec 31, 2023 -7.66 Mn
Sep 30, 2023 -5.23 Mn
Jun 30, 2023 -8.19 Mn
Mar 31, 2023 -9.96 Mn
Dec 31, 2022 -8.86 Mn
Sep 30, 2022 3.19 Mn
Jun 30, 2022 -12.99 Mn
Mar 31, 2022 -22.05 Mn
Dec 31, 2021 -17.96 Mn
Sep 30, 2021 -16.46 Mn
Jun 30, 2021 -17.13 Mn
Mar 31, 2021 -30.58 Mn
Dec 31, 2020 -16.34 Mn
Sep 30, 2020 -13.28 Mn
Jun 30, 2020 -11.82 Mn
Mar 31, 2020 -31.41 Mn
Dec 31, 2019 -5.72 Mn
Sep 30, 2019 -2.86 Mn
Jun 30, 2019 -2.55 Mn
Mar 31, 2019 -5.00 Mn
Dec 31, 2018 -1.56 Mn
Sep 30, 2018 -24.31 Mn
Jun 30, 2018 -5.75 Mn
Mar 31, 2018 -3.75 Mn
Dec 31, 2017 -4.36 Mn
Sep 30, 2017 21.92 Mn
Jun 30, 2017 -1.77 Mn
Mar 31, 2017 -1.90 Mn
Dec 31, 2016 -1.69 Mn
Sep 30, 2016 -5.96 Mn
Jun 30, 2016 -3.49 Mn
Mar 31, 2016 -4.94 Mn
Dec 31, 2015 -3.68 Mn
Sep 30, 2015 -1.96 Mn
Jun 30, 2015 -2.89 Mn
Mar 31, 2015 -2.48 Mn
Dec 31, 2014 -3.83 Mn
Sep 30, 2014 -6.00 Mn