Avalo Therapeutics (AVTX) EBIT Margin (2016 - 2025)

Avalo Therapeutics posted quarterly EBIT Margin of 33461.02% for Q4 2025, down 2652820.0% year-on-year from N/an in Q4 2024, and down 382.65% on a QoQ basis from 6932.81% in Q4 2024.

Avalo Therapeutics (AVTX) has 10 years of EBIT Margin data on file, last reported at 33461.02% in Q4 2025.

  • For the quarter ending Q4 2025, EBIT Margin fell 2652820.0% year-over-year to 33461.02%; the trailing twelve-month figure through Dec 2025 stood at 14585.0% (up 95105.0% YoY), and the FY2025 full-year result was 123601.69%, down 10806609.0% from the prior year.
  • EBIT Margin for Q4 2025 stood at 33461.02%, down from 6932.81% in the prior quarter.
  • Across five years, EBIT Margin topped out at 27.39% in Q3 2022 and bottomed at 33461.02% in Q4 2025.
  • The 5-year median for EBIT Margin is 1588.98% (2023), against an average of 4782.2%.
  • The widest annual swing landed in 2022, when EBIT Margin jumped 721400 bps; it then plunged 2652820 bps in 2025.
  • A 5-year view of EBIT Margin shows it stood at 8202.28% in 2021, then jumped by 88 bps to 988.28% in 2022, then slumped by 36 bps to 1341.16% in 2023, then sank by 417 bps to 6932.81% in 2024, then plunged by 383 bps to 33461.02% in 2025.
  • The last three EBIT Margin figures came in at 33461.02% (Q4 2025), 6932.81% (Q4 2024), and 5165.06% (Q3 2024), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Avalo Therapeutics 317.29 Mn 317.29 Mn - -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -33,461.02%
Dec 31, 2024 -6,932.81%
Sep 30, 2024 -5,165.06%
Dec 31, 2023 -1,341.16%
Sep 30, 2023 -1,588.98%
Jun 30, 2023 -1,111.98%
Mar 31, 2023 -1,850.95%
Dec 31, 2022 -988.28%
Sep 30, 2022 27.39%
Jun 30, 2022 -1,145.01%
Mar 31, 2022 -1,777.75%
Dec 31, 2021 -8,202.28%
Sep 30, 2021 -1,219.48%
Jun 30, 2021 -510.55%
Mar 31, 2021 -6,465.12%
Dec 31, 2020 -1,091.45%
Sep 30, 2020 -1,195.05%
Jun 30, 2020 -883.03%
Mar 31, 2020 -1,140.63%
Dec 31, 2019 -985.32%
Sep 30, 2019 -130.00%
Jun 30, 2019 -183.06%
Mar 31, 2019 -194.26%
Dec 31, 2018 24.67%
Sep 30, 2018 -596.68%
Jun 30, 2018 -120.22%
Mar 31, 2018 -83.75%
Dec 31, 2017 -228.00%
Sep 30, 2017 87.55%
Jun 30, 2017 -1,124.84%
Mar 31, 2017 -494.30%
Dec 31, 2016 -926.56%
Sep 30, 2016 -1,854.85%
Jun 30, 2016 -536.22%