Autolus Therapeutics (AUTL) Return on Capital Employed (2018 - 2025)

Autolus Therapeutics (AUTL) posted quarterly Return on Capital Employed of 49.01% for Q4 2025, down 1657.0% year-on-year from 3.15% in Q4 2024, and down 8.84% on a QoQ basis from 45.03% in Q3 2025.

Autolus Therapeutics (AUTL) Return on Capital Employed (2018 - 2025) Analysis & Trends

Autolus Therapeutics (AUTL) has reported Return on Capital Employed for 7 consecutive years, with 49.01% the latest figure, recorded in Q4 2025.

  • Quarterly Return on Capital Employed fell 1657.0% year-over-year to 49.01% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 49.01% (down 1657.0% YoY) and the FY2025 annual result came in at 44.17%, up 241.0% from the prior year.
  • Return on Capital Employed eased to 49.01% in Q4 2025 per AUTL's latest filing, from 45.03% in the prior quarter.
  • Over the last five years, Return on Capital Employed for AUTL reached as high as 23.17% in Q2 2024 and fell as low as 59.22% in Q3 2021.
  • A 5-year average of 41.3% and a median of 39.6% in 2022 frame the typical range for Return on Capital Employed.
  • Annual changes were most pronounced in 2021 — Return on Capital Employed slumped 4557 bps — and 2022, when it jumped 1956 bps.
  • Year by year, Return on Capital Employed stood at 43.73% in 2021, then rose by 14 bps to 37.57% in 2022, then tumbled by 38 bps to 51.94% in 2023, then jumped by 38 bps to 32.43% in 2024, then plunged by 51 bps to 49.01% in 2025.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 49.01%, 45.03%, and 40.6% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Autolus Therapeutics 404.53 Mn 103.82 Mn -1.04 Mn -49.01%

Historic Data

Download Data
DateValue
Dec 31, 2025 -49.01%
Sep 30, 2025 -45.03%
Jun 30, 2025 -40.60%
Mar 31, 2025 -38.39%
Dec 31, 2024 -32.43%
Sep 30, 2024 -27.77%
Jun 30, 2024 -23.17%
Mar 31, 2024 -30.17%
Dec 31, 2023 -51.94%
Sep 30, 2023 -35.31%
Jun 30, 2023 -31.98%
Mar 31, 2023 -29.21%
Dec 31, 2022 -37.57%
Sep 30, 2022 -54.26%
Jun 30, 2022 -45.71%
Mar 31, 2022 -38.59%
Dec 31, 2021 -43.73%
Sep 30, 2021 -59.22%
Jun 30, 2021 -53.73%
Mar 31, 2021 -58.15%