Autolus Therapeutics (AUTL) Net Margin (2017 - 2026)

Autolus Therapeutics' (AUTL) quarterly Net Margin came in at 372.02% in Q4 2025, up 9482108.0% YoY from N/an in Q4 2024, and little changed on a QoQ basis from 373.3% in Q3 2025.

Autolus Therapeutics (AUTL) Net Margin (2017 - 2026) Analysis & Trends

Autolus Therapeutics (AUTL) has 9 years of Net Margin data on file, last reported at 372.02% in Q4 2025.

  • Quarterly Net Margin rose 9482108.0% year-over-year to 372.02% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 381.43% (up 179708.0% YoY) and the FY2025 annual result came in at 381.43%, up 179902.0% from the prior year.
  • Net Margin was little changed at 372.02% in Q4 2025, from 373.3% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 229.02% in Q2 2025 to a low of 95193.1% in Q4 2024.
  • A 5-year average of 11834.6% and a median of 2003.27% in 2021 frame the typical range for Net Margin.
  • Annual changes were most pronounced in 2022 — Net Margin tumbled 995996 bps — and 2025, when it soared 9482108 bps.
  • Tracing AUTL's Net Margin over 5 years: stood at 14402.97% in 2021, then surged by 95 bps to 737.33% in 2022, then plunged by 1432 bps to 11292.86% in 2023, then slumped by 743 bps to 95193.1% in 2024, then soared by 100 bps to 372.02% in 2025.
  • The last three Net Margin figures came in at 372.02% (Q4 2025), 373.3% (Q3 2025), and 229.02% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Autolus Therapeutics 763.37 Mn 561.74 Mn 25.22 Mn -85.60%

Historic Data

Download Data
DateValue
Jun 30, 2026 -85.60%
Dec 31, 2025 -372.02%
Sep 30, 2025 -373.30%
Jun 30, 2025 -229.02%
Mar 31, 2025 -781.13%
Dec 31, 2024 -95,193.10%
Mar 31, 2024 -521.68%
Sep 30, 2023 -11,292.86%
Mar 31, 2023 -3,081.35%
Dec 31, 2022 -737.33%
Sep 30, 2022 -1,805.28%
Mar 31, 2022 -22,326.51%
Sep 30, 2021 -14,402.97%
Jun 30, 2021 -2,201.26%
Mar 31, 2021 -12,366.54%
Dec 31, 2020 -10,604.46%
Sep 30, 2020 -8,511.42%
Jun 30, 2020 -10,936.86%
Mar 31, 2020 -8,836.98%
Jun 30, 2019 -2,417.51%