Autolus Therapeutics (AUTL) Free Cash Flow (2017 - 2025)

Autolus Therapeutics (AUTL) posted quarterly Free Cash Flow of -$66.4 million for Q4 2025, down 35.46% year-on-year from -$102.9 million in Q4 2024, and up 8.12% on a QoQ basis from -$72.3 million in Q3 2025.

Autolus Therapeutics (AUTL) Free Cash Flow (2017 - 2025) Analysis & Trends

Autolus Therapeutics (AUTL) has reported Free Cash Flow for 9 consecutive years, with -$66.4 million the latest figure, recorded in Q4 2025.

  • Quarterly Free Cash Flow fell 35.46% year-over-year to -$66.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$302.6 million (down 32.52% YoY) and the FY2025 annual result came in at -$302.6 million, down 32.52% from the prior year.
  • Free Cash Flow grew to -$66.4 million in Q4 2025 per AUTL's latest filing, from -$72.3 million in the prior quarter.
  • Over the last five years, Free Cash Flow for AUTL reached as high as -$10.7 million in Q4 2021 and fell as low as -$86.3 million in Q3 2024.
  • A 5-year average of -$46.9 million and a median of -$41.4 million in 2023 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2021 — Free Cash Flow jumped 67.64% — and 2024, when it sank 107.09%.
  • Year by year, Free Cash Flow stood at -$10.7 million in 2021, then plunged by 41.48% to -$15.2 million in 2022, then sank by 73.1% to -$26.3 million in 2023, then plunged by 86.42% to -$49.0 million in 2024, then slumped by 35.46% to -$66.4 million in 2025.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$66.4 million, -$72.3 million, and -$80.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Autolus Therapeutics 404.53 Mn 103.82 Mn -1.04 Mn -66.44 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -66.44 Mn
Dec 31, 2025 -66.44 Mn
Sep 30, 2025 -72.31 Mn
Sep 30, 2025 -72.31 Mn
Jun 30, 2025 -80.06 Mn
Jun 30, 2025 -80.06 Mn
Mar 31, 2025 -83.81 Mn
Mar 31, 2025 -83.81 Mn
Dec 31, 2024 -49.05 Mn
Dec 31, 2024 -49.05 Mn
Sep 30, 2024 -86.33 Mn
Sep 30, 2024 -86.33 Mn
Jun 30, 2024 -51.90 Mn
Jun 30, 2024 -51.90 Mn
Mar 31, 2024 -41.07 Mn
Mar 31, 2024 -41.07 Mn
Dec 31, 2023 -26.31 Mn
Dec 31, 2023 -26.31 Mn
Sep 30, 2023 -41.69 Mn
Sep 30, 2023 -41.69 Mn