Autolus Therapeutics (AUTL) Free Cash Flow (2017 - 2025)

Autolus Therapeutics posted quarterly Free Cash Flow of -$48.6 million for Q4 2025, down 68.81% year-on-year from -$155.7 million in Q4 2024, and up 32.85% on a QoQ basis from -$72.3 million in Q3 2025.

Autolus Therapeutics (AUTL) has 9 years of Free Cash Flow data on file, last reported at -$48.6 million in Q4 2025.

  • For the quarter ending Q4 2025, Free Cash Flow fell 68.81% year-over-year to -$48.6 million; the trailing twelve-month figure through Dec 2025 stood at -$284.7 million (down 36.85% YoY), and the FY2025 full-year result was -$284.7 million, down 36.85% from the prior year.
  • Free Cash Flow for Q4 2025 stood at -$48.6 million, up from -$72.3 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$24.2 million in Q4 2022 and bottomed at -$86.3 million in Q3 2024.
  • The 5-year median for Free Cash Flow is -$36.6 million (2022), against an average of -$45.0 million.
  • The widest annual swing landed in 2021, when Free Cash Flow soared 51.01%; it then tumbled 104.07% in 2025.
  • A 5-year view of Free Cash Flow shows it stood at -$25.3 million in 2021, then gained by 4.35% to -$24.2 million in 2022, then declined by 8.77% to -$26.3 million in 2023, then decreased by 9.33% to -$28.8 million in 2024, then tumbled by 68.81% to -$48.6 million in 2025.
  • The last three Free Cash Flow figures came in at -$48.6 million (Q4 2025), -$72.3 million (Q3 2025), and -$80.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -1.67 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.29 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 848.30 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 48.67 Mn
10 Autolus Therapeutics - - -1.04 Mn -48.56 Mn

Historic Data

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DateValue
Dec 31, 2025 -48.56 Mn
Dec 31, 2025 -48.56 Mn
Sep 30, 2025 -72.31 Mn
Sep 30, 2025 -72.31 Mn
Jun 30, 2025 -80.06 Mn
Jun 30, 2025 -80.06 Mn
Mar 31, 2025 -83.81 Mn
Mar 31, 2025 -83.81 Mn
Dec 31, 2024 -28.76 Mn
Dec 31, 2024 -28.76 Mn
Sep 30, 2024 -86.33 Mn
Sep 30, 2024 -86.33 Mn
Jun 30, 2024 -51.90 Mn
Jun 30, 2024 -51.90 Mn
Mar 31, 2024 -41.07 Mn
Mar 31, 2024 -41.07 Mn
Dec 31, 2023 -26.31 Mn
Dec 31, 2023 -26.31 Mn
Sep 30, 2023 -47.44 Mn
Sep 30, 2023 -47.44 Mn
Jun 30, 2023 -36.72 Mn
Jun 30, 2023 -36.72 Mn
Mar 31, 2023 -46.11 Mn
Mar 31, 2023 -46.11 Mn
Dec 31, 2022 -24.19 Mn
Dec 31, 2022 -24.19 Mn
Sep 30, 2022 -36.53 Mn
Sep 30, 2022 -36.53 Mn
Jun 30, 2022 -28.17 Mn
Jun 30, 2022 -28.17 Mn
Mar 31, 2022 -34.26 Mn
Mar 31, 2022 -34.26 Mn
Dec 31, 2021 -25.29 Mn
Dec 31, 2021 -25.29 Mn
Sep 30, 2021 -30.89 Mn
Sep 30, 2021 -30.89 Mn
Jun 30, 2021 -35.10 Mn
Jun 30, 2021 -35.10 Mn
Mar 31, 2021 -35.44 Mn
Mar 31, 2021 -35.44 Mn
Dec 31, 2020 -51.62 Mn
Dec 31, 2020 -51.62 Mn
Sep 30, 2020 -35.01 Mn
Sep 30, 2020 -35.01 Mn
Jun 30, 2020 -24.41 Mn
Jun 30, 2020 -24.41 Mn
Mar 31, 2020 -21.40 Mn
Mar 31, 2020 -21.40 Mn
Jun 30, 2019 -30.76 Mn
Jun 30, 2019 -30.76 Mn
Mar 31, 2019 -19.19 Mn
Mar 31, 2019 -19.19 Mn
Sep 30, 2018 -31.54 Mn
Sep 30, 2018 -31.54 Mn
Jun 30, 2018 -8.92 Mn
Jun 30, 2018 -8.92 Mn
Mar 31, 2018 -8.13 Mn
Mar 31, 2018 -8.13 Mn
Dec 31, 2017 -8.80 Mn
Dec 31, 2017 -8.80 Mn