Autolus Therapeutics (AUTL) Enterprise Value (2017 - 2025)

Autolus Therapeutics posted quarterly Enterprise Value of -$105.6 million for Q4 2025, up 53.83% year-on-year from -$68.7 million in Q4 2024, and up 71.25% on a QoQ basis from -$367.4 million in Q3 2025.

Autolus Therapeutics (AUTL) has 9 years of Enterprise Value data on file, last reported at -$105.6 million in Q4 2025.

  • For the quarter ending Q4 2025, Enterprise Value rose 53.83% year-over-year to -$105.6 million; the trailing twelve-month figure through Dec 2025 stood at -$105.6 million (up 53.83% YoY), and the FY2025 full-year result was -$105.6 million, up 53.83% from the prior year.
  • Enterprise Value for Q4 2025 stood at -$105.6 million, up from -$367.4 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$97.3 million in Q1 2025 and bottomed at -$759.5 million in Q1 2024.
  • The 5-year median for Enterprise Value is -$248.6 million (2023), against an average of -$308.5 million.
  • The widest annual swing landed in 2021, when Enterprise Value slumped 39426.21%; it then surged 87.2% in 2025.
  • A 5-year view of Enterprise Value shows it stood at -$310.7 million in 2021, then slipped by 23.2% to -$382.8 million in 2022, then soared by 37.21% to -$240.3 million in 2023, then gained by 4.8% to -$228.8 million in 2024, then jumped by 53.83% to -$105.6 million in 2025.
  • The last three Enterprise Value figures came in at -$105.6 million (Q4 2025), -$367.4 million (Q3 2025), and -$125.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -2.32 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -32.30 Mn
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -901.90 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -61.46 Mn
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn -7.25 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -8.75 Bn
8 Evaxion A 65.12 Bn 65.10 Bn - -18.44 Mn
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn -3.01 Bn
10 Autolus Therapeutics - - -1.04 Mn -105.64 Mn

Historic Data

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DateValue
Dec 31, 2025 -105.64 Mn
Sep 30, 2025 -367.42 Mn
Jun 30, 2025 -125.33 Mn
Mar 31, 2025 -97.25 Mn
Dec 31, 2024 -228.81 Mn
Sep 30, 2024 -658.54 Mn
Jun 30, 2024 -706.96 Mn
Mar 31, 2024 -759.54 Mn
Dec 31, 2023 -240.34 Mn
Sep 30, 2023 -256.85 Mn
Jun 30, 2023 -307.83 Mn
Mar 31, 2023 -343.36 Mn
Dec 31, 2022 -382.76 Mn
Sep 30, 2022 -163.37 Mn
Jun 30, 2022 -216.76 Mn
Mar 31, 2022 -268.89 Mn
Dec 31, 2021 -310.68 Mn
Sep 30, 2021 -173.27 Mn
Jun 30, 2021 -216.56 Mn
Mar 31, 2021 -239.80 Mn
Dec 31, 2020 -786,000.00
Sep 30, 2020 -178.48 Mn
Jun 30, 2020 -212.83 Mn
Mar 31, 2020 -244.10 Mn
Dec 31, 2019 -211.43 Mn
Sep 30, 2019 -230.73 Mn
Jun 30, 2019 -267.56 Mn
Mar 31, 2019 -188.41 Mn
Dec 31, 2018 -217.56 Mn
Sep 30, 2018 -247.19 Mn
Jun 30, 2018 -264.92 Mn
Mar 31, 2018 -120.67 Mn
Sep 30, 2017 -137.07 Mn