Autolus Therapeutics (AUTL) EBITDA Margin (2017 - 2025)
Autolus Therapeutics posted quarterly EBITDA Margin of 373.7% for Q4 2025, up 19232285.0% year-on-year from N/an in Q4 2024, and up 6.71% on a QoQ basis from 400.59% in Q3 2025.
Autolus Therapeutics (AUTL) has 7 years of EBITDA Margin data on file, last reported at 373.7% in Q4 2025.
- For the quarter ending Q4 2025, EBITDA Margin rose 19232285.0% year-over-year to 373.7%; the trailing twelve-month figure through Dec 2025 stood at 349.8% (up 183051.0% YoY), and the FY2025 full-year result was 349.8%, up 183245.0% from the prior year.
- EBITDA Margin for Q4 2025 stood at 373.7%, up from 400.59% in the prior quarter.
- Across five years, EBITDA Margin topped out at 20932.13% in Q4 2021 and bottomed at 192696.55% in Q4 2024.
- The 5-year median for EBITDA Margin is 400.59% (2025), against an average of 14224.24%.
- The widest annual swing landed in 2022, when EBITDA Margin plunged 3871078 bps; it then jumped 19232285 bps in 2025.
- A 5-year view of EBITDA Margin shows it stood at 20932.13% in 2021, then tumbled by 228 bps to 26817.47% in 2022, then soared by 53 bps to 12730.54% in 2023, then slumped by 1414 bps to 192696.55% in 2024, then soared by 100 bps to 373.7% in 2025.
- The last three EBITDA Margin figures came in at 373.7% (Q4 2025), 400.59% (Q3 2025), and 138.36% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | - |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 38.10% |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 18.35% |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 17.24% |
| 10 | Autolus Therapeutics | - | - | -1.04 Mn | -373.70% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -373.70% |
| Sep 30, 2025 | -400.59% |
| Jun 30, 2025 | -138.36% |
| Mar 31, 2025 | -657.90% |
| Dec 31, 2024 | -192,696.55% |
| Mar 31, 2024 | -521.11% |
| Sep 30, 2023 | -12,730.54% |
| Mar 31, 2023 | -2,644.74% |
| Mar 31, 2022 | -26,817.47% |
| Dec 31, 2021 | 20,932.13% |
| Sep 30, 2021 | 17,141.53% |
| Jun 30, 2021 | 2,098.94% |
| Mar 31, 2021 | 11,893.31% |
| Dec 31, 2020 | -61,163.86% |
| Sep 30, 2020 | 6,027.40% |
| Jun 30, 2020 | 11,557.68% |
| Mar 31, 2020 | 14,075.15% |
| Dec 31, 2017 | -3,861.90% |