Assembly Biosciences (ASMB) EBITDA Margin (2017 - 2026)

Assembly Biosciences (ASMB) recorded quarterly EBITDA Margin of 114.53% in Q1 2026, down 319.69% quarter-over-quarter from 52.13% in Q4 2025, and down 2046.0% on a YoY basis from 5.89% in Q1 2025.

Assembly Biosciences (ASMB) EBITDA Margin (2017 - 2026) Analysis & Trends

Assembly Biosciences' EBITDA Margin history runs 9 years deep, the most recent figure standing at 114.53% for Q1 2026.

  • In Q1 2026, EBITDA Margin fell 2046.0% year-over-year to 114.53%; the TTM figure through Mar 2026 stood at 9.14% (up 11505.0% YoY), while the FY2025 annual figure was 8.23%, up 13310.0% from the prior year.
  • EBITDA Margin was 114.53% for Q1 2026 at Assembly Biosciences, down from 52.13% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 52.13% in Q4 2025 to a low of 159.64% in Q1 2024.
  • Historically, EBITDA Margin has averaged 106.71% across 4 years, with a median of 122.93% in 2024.
  • The sharpest annual moves came in 2025 and 2026: EBITDA Margin soared 19336 bps in 2025, then slumped 2046 bps in 2026.
  • A 4-year view of EBITDA Margin shows it stood at 150.33% in 2023, then gained by 6 bps to 141.23% in 2024, then jumped by 137 bps to 52.13% in 2025, then sank by 320 bps to 114.53% in 2026.
  • The last three EBITDA Margin figures came in at 114.53% (Q1 2026), 52.13% (Q4 2025), and 83.48% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Assembly Biosciences 418.96 Mn 192.36 Mn - -114.53%

Historic Data

Download Data
DateValue
Mar 31, 2026 -114.53%
Dec 31, 2025 52.13%
Sep 30, 2025 -83.48%
Jun 30, 2025 -106.21%
Mar 31, 2025 -94.07%
Dec 31, 2024 -141.23%
Sep 30, 2024 -138.44%
Jun 30, 2024 -131.33%
Mar 31, 2024 -159.64%
Dec 31, 2023 -150.33%
Sep 30, 2021 -300.90%
Dec 31, 2020 -3,811.96%
Sep 30, 2020 -10.43%
Jun 30, 2020 18.95%
Mar 31, 2020 -650.33%
Dec 31, 2019 -568.07%
Sep 30, 2019 -591.18%
Jun 30, 2019 -599.06%
Mar 31, 2019 -693.54%
Dec 31, 2018 -700.21%