Aprea Therapeutics APRE
NASDAQ APRE
$0.63 -0.04 (-5.97%)
At close: Aug 20, 2026 · 4:00 PM EDT

Aprea Therapeutics (APRE) Research & Development (2018 - 2026)

Aprea Therapeutics (APRE) posted quarterly Research & Development of $1.6 million for Q1 2026, down 35.11% year-over-year from $2.5 million in Q1 2025, and up 59.71% quarter-over-quarter from $1.0 million in Q4 2025.

Aprea Therapeutics (APRE) Research & Development (2018 - 2026) Analysis & Trends

Aprea Therapeutics (APRE) has reported Research & Development for 9 consecutive years, with $1.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Research & Development fell 35.11% year-over-year to $1.6 million; the TTM figure through Mar 2026 stood at $6.2 million (down 39.77% YoY), while the FY2025 annual figure was $7.0 million, down 24.78% from the prior year.
  • Research & Development advanced to $1.6 million in Q1 2026 per APRE's latest filing, from $1.0 million in the prior quarter.
  • Across five years, Research & Development topped out at $6.8 million in Q2 2022 and bottomed at $531406.0 in Q4 2022.
  • Historically, Research & Development has averaged $2.2 million across 5 years, with a median of $2.0 million in 2023.
  • Annual changes were most pronounced in 2022 — Research & Development tumbled 88.09% — and 2023, when it surged 284.96%.
  • Aprea Therapeutics' Research & Development stood at $531406.0 in 2022, then soared by 284.96% to $2.0 million in 2023, then increased by 15.32% to $2.4 million in 2024, then slumped by 57.24% to $1.0 million in 2025, then jumped by 59.71% to $1.6 million in 2026.
  • Business Quant data shows APRE's Research & Development at $1.6 million in Q1 2026, $1.0 million in Q4 2025, and $1.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn 1.37 Bn
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn 651.00 Mn
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 612.28 Mn
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 413.13 Mn
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn 210.03 Mn
8 Royalty Pharma 26.98 Bn 26.14 Bn - 97.90 Mn
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -588.31 Mn
10 Aprea Therapeutics 34.28 Mn 34.28 Mn - 2.46 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 2.46 Mn
Mar 31, 2026 1.61 Mn
Dec 31, 2025 1.01 Mn
Sep 30, 2025 1.64 Mn
Jun 30, 2025 1.91 Mn
Mar 31, 2025 2.48 Mn
Dec 31, 2024 2.36 Mn
Sep 30, 2024 2.85 Mn
Jun 30, 2024 2.56 Mn
Mar 31, 2024 1.60 Mn
Dec 31, 2023 2.05 Mn
Sep 30, 2023 2.12 Mn
Jun 30, 2023 2.20 Mn
Mar 31, 2023 1.26 Mn
Dec 31, 2022 531,406.00
Sep 30, 2022 1.12 Mn
Jun 30, 2022 6.81 Mn
Mar 31, 2022 4.09 Mn
Dec 31, 2021 4.46 Mn
Sep 30, 2021 6.02 Mn