Aprea Therapeutics APRE
NASDAQ APRE
$0.62 -0.01 (-1.48%)
As of: Aug 21, 2026 · 11:53 AM EDT

Aprea Therapeutics (APRE) Enterprise Value (2018 - 2026)

Aprea Therapeutics (APRE) posted quarterly Enterprise Value of -$46.5 million for Q1 2026, down 141.06% year-over-year from $113.2 million in Q1 2025, and down 218.28% quarter-over-quarter from -$14.6 million in Q4 2025.

Aprea Therapeutics (APRE) Enterprise Value (2018 - 2026) Analysis & Trends

Aprea Therapeutics (APRE) has reported Enterprise Value for 9 consecutive years, with -$46.5 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Enterprise Value fell 141.06% year-over-year to -$46.5 million; the TTM figure through Mar 2026 stood at -$46.5 million (down 141.06% YoY), while the FY2025 annual figure was -$14.6 million, up 36.11% from the prior year.
  • Enterprise Value fell to -$46.5 million in Q1 2026 per APRE's latest filing, from -$14.6 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$13.7 million in Q3 2025 and bottomed at -$47.7 million in Q1 2022.
  • Historically, Enterprise Value has averaged -$27.9 million across 5 years, with a median of -$27.7 million in 2023.
  • Annual changes were most pronounced in 2025 — Enterprise Value soared 47.74% — and 2026, when it slumped 141.06%.
  • Aprea Therapeutics' Enterprise Value stood at -$28.8 million in 2022, then increased by 24.94% to -$21.6 million in 2023, then slipped by 5.75% to -$22.8 million in 2024, then soared by 36.11% to -$14.6 million in 2025, then sank by 218.28% to -$46.5 million in 2026.
  • Business Quant data shows APRE's Enterprise Value at -$46.5 million in Q1 2026, -$14.6 million in Q4 2025, and -$13.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 139.69 Bn 131.84 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 86.46 Bn 78.47 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 65.62 Bn 60.44 Bn 1.37 Bn -5.18 Bn
4 Moderna 58.37 Bn 53.24 Bn 52.00 Mn -5.14 Bn
5 BeOne Medicines 42.17 Bn 37.07 Bn 1.53 Bn -5.10 Bn
6 Alnylam Pharmaceuticals 31.73 Bn 28.43 Bn 992.69 Mn -3.31 Bn
7 BioNTech SE 28.27 Bn 9.87 Bn 668.28 Mn -18.39 Bn
8 Insmed 27.58 Bn 26.42 Bn 358.27 Mn -1.16 Bn
9 Royalty Pharma 27.23 Bn 26.40 Bn - 2.12 Bn
10 Aprea Therapeutics 33.32 Mn 33.32 Mn - -41.23 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -41.23 Mn
Mar 31, 2026 -46.47 Mn
Dec 31, 2025 -14.60 Mn
Sep 30, 2025 -13.72 Mn
Jun 30, 2025 -16.50 Mn
Mar 31, 2025 -19.28 Mn
Dec 31, 2024 -22.85 Mn
Sep 30, 2024 -26.25 Mn
Jun 30, 2024 -28.69 Mn
Mar 31, 2024 -32.37 Mn
Dec 31, 2023 -21.61 Mn
Sep 30, 2023 -25.35 Mn
Jun 30, 2023 -27.69 Mn
Mar 31, 2023 -31.00 Mn
Dec 31, 2022 -28.79 Mn
Sep 30, 2022 -33.11 Mn
Jun 30, 2022 -39.06 Mn
Mar 31, 2022 -47.65 Mn
Dec 31, 2021 -53.08 Mn
Sep 30, 2021 -61.43 Mn