Apogee Therapeutics (APGE) Operating Income (2022 - 2026)

Apogee Therapeutics (APGE) reported Operating Income of -$82.8 million for Q1 2026, down 31.18% year-over-year from -$120.3 million in Q1 2025, and down 153.79% quarter-over-quarter from $153.9 million in Q4 2025.

Apogee Therapeutics (APGE) Operating Income (2022 - 2026) Analysis & Trends

Apogee Therapeutics (APGE) has 5 years of Operating Income data on file, last reported at -$82.8 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$82.8 million, down 31.18% year-over-year; the trailing twelve-month figure through Mar 2026 was -$73.3 million (down 16.12% YoY), and the FY2025 annual result was -$53.7 million, down 40.32% from the prior year.
  • Operating Income slipped to -$82.8 million in Q1 2026 per APGE's latest filing, from $153.9 million in the prior quarter.
  • Over five years, Operating Income peaked at $153.9 million in Q4 2025 and troughed at -$82.8 million in Q1 2026.
  • A 5-year average of -$13.7 million and a median of -$21.6 million in 2023 frame the typical range for Operating Income.
  • On a YoY basis, Operating Income climbed as much as 371.02% in 2023 and fell as far as 939.92% in 2023.
  • A 5-year view of Operating Income shows it stood at -$14.1 million in 2022, then jumped by 371.02% to $38.2 million in 2023, then soared by 168.88% to $102.7 million in 2024, then surged by 49.76% to $153.9 million in 2025, then plunged by 153.79% to -$82.8 million in 2026.
  • Business Quant data shows APGE's Operating Income at -$82.8 million in Q1 2026, $153.9 million in Q4 2025, and -$71.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Apogee Therapeutics 6.29 Bn 5.23 Bn - -82.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -82.77 Mn
Dec 31, 2025 153.87 Mn
Sep 30, 2025 -71.28 Mn
Jun 30, 2025 -73.17 Mn
Mar 31, 2025 -63.10 Mn
Dec 31, 2024 102.74 Mn
Sep 30, 2024 -58.69 Mn
Jun 30, 2024 -44.12 Mn
Mar 31, 2024 -38.18 Mn
Dec 31, 2023 38.21 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -18.89 Mn
Mar 31, 2023 -12.66 Mn
Dec 31, 2022 -14.10 Mn
Sep 30, 2022 -10.51 Mn
Jun 30, 2022 -1.82 Mn