Apogee Therapeutics (APGE) EBITDA (2022 - 2026)

Apogee Therapeutics' (APGE) quarterly EBITDA came in at -$82.8 million in Q1 2026, down 31.18% year-on-year from -$120.3 million in Q1 2025, and down 6.04% on a QoQ basis from -$78.1 million in Q4 2025.

Apogee Therapeutics (APGE) EBITDA (2022 - 2026) Analysis & Trends

Apogee Therapeutics (APGE) has 5 years of EBITDA data on file, last reported at -$82.8 million in Q1 2026.

  • On a quarterly basis, EBITDA fell 31.18% year-over-year to -$82.8 million in Q1 2026; TTM through Mar 2026 was -$305.3 million, a 26.26% decrease from a year earlier, with the FY2025 full-year figure at -$285.6 million, down 31.69% from the prior year.
  • EBITDA for Q1 2026 stood at -$82.8 million, down from -$78.1 million in the prior quarter.
  • Over the last five years, EBITDA for APGE reached as high as -$1.8 million in Q2 2022 and fell as low as -$82.8 million in Q1 2026.
  • Historically, EBITDA has averaged -$44.0 million across 5 years, with a median of -$41.2 million in 2024.
  • Across the five-year window, EBITDA slumped 939.92% in 2023 and fell 2.87% in 2025, its largest moves.
  • Year by year, EBITDA stood at -$14.1 million in 2022, then tumbled by 163.53% to -$37.2 million in 2023, then sank by 104.23% to -$75.9 million in 2024, then decreased by 2.87% to -$78.1 million in 2025, then retreated by 6.04% to -$82.8 million in 2026.
  • Per Business Quant data, the three most recent EBITDA figures were -$82.8 million in Q1 2026, -$78.1 million in Q4 2025, and -$71.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Apogee Therapeutics 9.35 Bn 8.29 Bn - -82.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -82.77 Mn
Dec 31, 2025 -78.06 Mn
Sep 30, 2025 -71.28 Mn
Jun 30, 2025 -73.17 Mn
Mar 31, 2025 -63.10 Mn
Dec 31, 2024 -75.88 Mn
Sep 30, 2024 -58.69 Mn
Jun 30, 2024 -44.12 Mn
Mar 31, 2024 -38.18 Mn
Dec 31, 2023 -37.16 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -18.89 Mn
Mar 31, 2023 -12.66 Mn
Dec 31, 2022 -14.10 Mn
Sep 30, 2022 -10.51 Mn
Jun 30, 2022 -1.82 Mn