Apogee Therapeutics (APGE) EBITDA (2022 - 2026)

Apogee Therapeutics (APGE) reported EBITDA of -$82.8 million for Q1 2026, down 31.18% year-over-year from -$120.3 million in Q1 2025, and down 153.79% quarter-over-quarter from $153.9 million in Q4 2025.

Apogee Therapeutics (APGE) EBITDA (2022 - 2026) Analysis & Trends

Apogee Therapeutics (APGE) has 5 years of EBITDA data on file, last reported at -$82.8 million in Q1 2026.

  • EBITDA for Q1 2026 came in at -$82.8 million, down 31.18% year-over-year; the trailing twelve-month figure through Mar 2026 was -$73.3 million (down 84.56% YoY), and the FY2025 annual result was -$53.7 million, down 40.32% from the prior year.
  • EBITDA slipped to -$82.8 million in Q1 2026 per APGE's latest filing, from $153.9 million in the prior quarter.
  • Over five years, EBITDA peaked at $153.9 million in Q4 2025 and troughed at -$82.8 million in Q1 2026.
  • A 5-year average of -$16.6 million and a median of -$26.1 million in 2023 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2023 and 2024: EBITDA plunged 939.92% in 2023, then surged 425.74% in 2024.
  • A 5-year view of EBITDA shows it stood at -$14.0 million in 2022, then plunged by 125.18% to -$31.5 million in 2023, then surged by 425.74% to $102.7 million in 2024, then surged by 49.76% to $153.9 million in 2025, then plunged by 153.79% to -$82.8 million in 2026.
  • Business Quant data shows APGE's EBITDA at -$82.8 million in Q1 2026, $153.9 million in Q4 2025, and -$71.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Apogee Therapeutics 6.29 Bn 5.23 Bn - -82.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -82.77 Mn
Dec 31, 2025 153.87 Mn
Sep 30, 2025 -71.28 Mn
Jun 30, 2025 -73.17 Mn
Mar 31, 2025 -63.10 Mn
Dec 31, 2024 102.74 Mn
Sep 30, 2024 -45.46 Mn
Jun 30, 2024 -33.93 Mn
Mar 31, 2024 -32.60 Mn
Dec 31, 2023 -31.54 Mn
Sep 30, 2023 -20.71 Mn
Jun 30, 2023 -18.89 Mn
Mar 31, 2023 -12.53 Mn
Dec 31, 2022 -14.01 Mn
Sep 30, 2022 -19.66 Mn
Jun 30, 2022 -1.82 Mn