Growth Metrics

Apogee Therapeutics (APGE) EBIT (2022 - 2026)

Apogee Therapeutics (APGE) reported EBIT of -$82.8 million for Q1 2026, down 31.18% year-over-year from -$120.3 million in Q1 2025, and down 153.79% on a QoQ basis from $153.9 million in Q4 2025.

Apogee Therapeutics (APGE) has 5 years of EBIT data on file, last reported at -$82.8 million in Q1 2026.

  • Quarterly EBIT fell 31.18% year-over-year to -$82.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$73.3 million (down 16.12% YoY) and the FY2025 annual result came in at -$53.7 million, down 40.32% from the prior year.
  • EBIT eased to -$82.8 million in Q1 2026 per APGE's latest filing, from $153.9 million in the prior quarter.
  • Across five years, EBIT topped out at $153.9 million in Q4 2025 and bottomed at -$82.8 million in Q1 2026.
  • The 5-year median for EBIT is -$21.6 million (2023), against an average of -$13.7 million.
  • Peak annual rise in EBIT reached 371.02% in 2023, while the deepest fall reached 939.92% in 2023.
  • Tracing APGE's EBIT over 5 years: stood at -$14.1 million in 2022, then surged by 371.02% to $38.2 million in 2023, then jumped by 168.88% to $102.7 million in 2024, then soared by 49.76% to $153.9 million in 2025, then slumped by 153.79% to -$82.8 million in 2026.
  • Per Business Quant, the three latest APGE EBIT figures stand at -$82.8 million (Q1 2026), $153.9 million (Q4 2025), and -$71.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Apogee Therapeutics 5.53 Bn 4.47 Bn - -82.77 Mn

Historic Data

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DateValue
Mar 31, 2026 -82.77 Mn
Dec 31, 2025 153.87 Mn
Sep 30, 2025 -71.28 Mn
Jun 30, 2025 -73.17 Mn
Mar 31, 2025 -63.10 Mn
Dec 31, 2024 102.74 Mn
Sep 30, 2024 -58.69 Mn
Jun 30, 2024 -44.12 Mn
Mar 31, 2024 -38.18 Mn
Dec 31, 2023 38.21 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -18.89 Mn
Mar 31, 2023 -12.66 Mn
Dec 31, 2022 -14.10 Mn
Sep 30, 2022 -10.51 Mn
Jun 30, 2022 -1.82 Mn