AN2 Therapeutics (ANTX) Operating Income (2021 - 2026)

AN2 Therapeutics (ANTX) reported Operating Income of -$10.6 million for Q1 2026, up 8.55% year-over-year from -$9.7 million in Q1 2025, and down 13.26% quarter-over-quarter from -$9.3 million in Q4 2025.

AN2 Therapeutics (ANTX) Operating Income (2021 - 2026) Analysis & Trends

AN2 Therapeutics (ANTX) has 6 years of Operating Income data on file, last reported at -$10.6 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$10.6 million, up 8.55% year-over-year; the trailing twelve-month figure through Mar 2026 was -$37.1 million (up 25.8% YoY), and the FY2025 annual result was -$38.1 million, up 32.89% from the prior year.
  • Operating Income eased to -$10.6 million in Q1 2026 per ANTX's latest filing, from -$9.3 million in the prior quarter.
  • Over five years, Operating Income peaked at -$7.2 million in Q2 2025 and troughed at -$18.8 million in Q4 2023.
  • A 5-year average of -$12.8 million and a median of -$11.8 million in 2022 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2022 and 2025: Operating Income plunged 274.78% in 2022, then surged 54.56% in 2025.
  • A 5-year view of Operating Income shows it stood at -$12.5 million in 2022, then plunged by 50.81% to -$18.8 million in 2023, then jumped by 54.3% to -$8.6 million in 2024, then declined by 8.35% to -$9.3 million in 2025, then retreated by 13.26% to -$10.6 million in 2026.
  • Business Quant data shows ANTX's Operating Income at -$10.6 million in Q1 2026, -$9.3 million in Q4 2025, and -$10.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -15.76 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 AN2 Therapeutics 161.95 Mn 161.95 Mn - -10.55 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -10.55 Mn
Dec 31, 2025 -9.32 Mn
Sep 30, 2025 -10.04 Mn
Jun 30, 2025 -7.22 Mn
Mar 31, 2025 -11.54 Mn
Dec 31, 2024 -8.60 Mn
Sep 30, 2024 -14.01 Mn
Jun 30, 2024 -15.88 Mn
Mar 31, 2024 -18.30 Mn
Dec 31, 2023 -18.82 Mn
Sep 30, 2023 -18.18 Mn
Jun 30, 2023 -16.60 Mn
Mar 31, 2023 -16.04 Mn
Dec 31, 2022 -12.48 Mn
Sep 30, 2022 -11.77 Mn
Jun 30, 2022 -10.33 Mn
Mar 31, 2022 -7.68 Mn
Dec 31, 2021 -7.59 Mn
Sep 30, 2021 -6.93 Mn
Jun 30, 2021 -5.00 Mn