Alto Neuroscience (ANRO) Return on Capital Employed (2024 - 2026)

Alto Neuroscience's (ANRO) quarterly Return on Capital Employed came in at 35.81% in Q1 2026, up 593.0% year-on-year from 5.17% in Q1 2025, and up 16.63% quarter-over-quarter from 42.95% in Q4 2025.

Alto Neuroscience (ANRO) Return on Capital Employed (2024 - 2026) Analysis & Trends

Alto Neuroscience has disclosed Return on Capital Employed across 3 years of filings, most recently posting 35.81% for Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 35.81%, up 593.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 35.81% (up 593.0% YoY), and the FY2025 annual result was 39.09%, up 1712.0% from the prior year.
  • Return on Capital Employed came in at 35.81% for Q1 2026 at Alto Neuroscience, up from 42.95% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 27.97% in Q2 2024 to a low of 46.24% in Q3 2025.
  • The 3-year median for Return on Capital Employed is 39.3% (2024), against an average of 38.45%.
  • Across the five-year window, Return on Capital Employed tumbled 1683 bps in 2025 and soared 593 bps in 2026, its largest moves.
  • Alto Neuroscience's Return on Capital Employed stood at 39.3% in 2024, then retreated by 9 bps to 42.95% in 2025, then gained by 17 bps to 35.81% in 2026.
  • The last three Return on Capital Employed figures came in at 35.81% (Q1 2026), 42.95% (Q4 2025), and 46.24% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 450.31%
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 51.73%
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -107.40%
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 21.10%
9 Abivax 91.71 Bn 91.71 Bn - -50.43%
10 Alto Neuroscience 643.06 Mn 379.30 Mn - -35.81%

Historic Data

Download Data
DateValue
Mar 31, 2026 -35.81%
Dec 31, 2025 -42.95%
Sep 30, 2025 -46.24%
Jun 30, 2025 -44.81%
Mar 31, 2025 -41.74%
Dec 31, 2024 -39.30%
Sep 30, 2024 -35.12%
Jun 30, 2024 -27.97%
Mar 31, 2024 -32.08%