Alto Neuroscience, Inc. (ANRO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

27,271,154Shares Outstanding

5,030,361Shares held by institutions

$96,884,753Value of institutional holdings

88.73%Institutional ownership %

45.82%Shares Changed QoQ

94No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Alto Neuroscience, Inc. (NYSE:ANRO) is held by 94 institutional firms.

Institutional ownership in Alto Neuroscience edged up to 88.7% in December 2025, compared to 62.1% in September 2025.
In percentage terms, this reflects as a holdings change of 45.82% quarter on quarter, and an increase of 23.68% year over year.
The latest 13F cycle for Alto Neuroscience reveals that of 94 total investors, 56 funds grew their exposure, whereas 24 reduced theirs and 14 made no changes.
The total number of shares held by institutions in Alto Neuroscience increased to 24.20Mn as of December 2025, a net change of up by 7.60Mn shares quarter on quarter, and up 1.78Mn shares year over year.
As of December 31, 2025, Alpha Wave Global, LP held Alto Neuroscience's largest shareholding position with over 3.71Mn shares, representing 13.60% of total outstanding shares.
Among the most significant buyers of Alto Neuroscience during December 2025 were Commodore Capital LP (1.82Mn), PERCEPTIVE ADVISORS LLC (1.63Mn), Vestal Point Capital, LP (1.53Mn), Vivo Capital, LLC (1.04Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (336.76K).
Leading sellers of Alto Neuroscience stock in December 2025 included MARSHALL WACE, LLP (632.12K), Almitas Capital LLC (311.77K), ORBIMED ADVISORS LLC (125.00K), UBS Group AG (120.54K), ARMISTICE CAPITAL, LLC (100.00K).
The top 10 institutional holders of Alto Neuroscience for the quarter ending December 2025 included Alpha Wave Global, LP (3.71Mn), Vestal Point Capital, LP (2.48Mn), Commodore Capital LP (1.82Mn), PERCEPTIVE ADVISORS LLC (1.78Mn), Point72 Asset Management, L.P. (1.61Mn), ARMISTICE CAPITAL, LLC (1.54Mn), VANGUARD GROUP INC (1.37Mn), FRANKLIN RESOURCES INC (1.12Mn), Vivo Capital, LLC (1.04Mn), 72 Investment Holdings, LLC (667.78K).

94 Institutional Holders

5,030,361 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Alpha Wave Global, LP	31 Dec, 2025	3,707,757	0	0.00%	$65,998,075.00
Vestal Point Capital, LP	31 Dec, 2025	2,485,000	1,535,000	161.58%	$44,233,000.00
Commodore Capital LP	31 Dec, 2025	1,823,196	1,823,196	0.00%	$32,452,889.00
PERCEPTIVE ADVISORS LLC	31 Dec, 2025	1,784,393	1,629,027	1,048.51%	$31,762,195.00
Point72 Asset Management, L.P.	31 Dec, 2025	1,606,954	274,517	20.60%	$28,603,781.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	1,536,000	-100,000	-6.11%	$27,340,800.00
VANGUARD GROUP INC	31 Dec, 2025	1,365,847	260,440	23.56%	$24,312,077.00
FRANKLIN RESOURCES INC	31 Dec, 2025	1,119,578	-43,030	-3.70%	$19,928,488.00
Vivo Capital, LLC	31 Dec, 2025	1,035,551	1,035,551	0.00%	$18,432,808.00
72 Investment Holdings, LLC	31 Dec, 2025	667,778	0	0.00%	$11,886,448.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	629,985	314,227	99.52%	$11,213,733.00
BlackRock, Inc.	31 Dec, 2025	607,874	239,995	65.24%	$10,820,158.00
ALKEON CAPITAL MANAGEMENT LLC	31 Dec, 2025	477,101	0	0.00%	$8,492,398.00
NORTHERN TRUST CORP	31 Dec, 2025	474,373	13,088	2.84%	$8,443,839.00
Integral Health Asset Management, LLC	31 Dec, 2025	375,000	-25,000	-6.25%	$6,675,000.00
DRIEHAUS CAPITAL MANAGEMENT LLC	31 Dec, 2025	336,762	336,762	0.00%	$5,994,364.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	287,435	49,535	20.82%	$5,118,477.00
Peapod Lane Capital LLC	31 Dec, 2025	253,992	-27,971	-9.92%	$4,521,058.00
JANE STREET GROUP, LLC	31 Dec, 2025	241,741	193,375	399.82%	$4,302,989.00
AWM Investment Company, Inc.	31 Dec, 2025	225,000	-55,483	-19.78%	$4,005,000.00

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