Annexon (ANNX) Free Cash Flow (2019 - 2026)

Annexon's (ANNX) quarterly Free Cash Flow came in at -$46.5 million in Q1 2026, up 7.2% year-on-year from -$43.4 million in Q1 2025, and up 8.96% quarter-over-quarter from -$51.1 million in Q4 2025.

Annexon (ANNX) Free Cash Flow (2019 - 2026) Analysis & Trends

Annexon's Free Cash Flow history runs 8 years deep, the most recent figure standing at -$46.5 million for Q1 2026.

  • On a quarterly basis, Free Cash Flow rose 7.2% year-over-year to -$46.5 million in Q1 2026; TTM through Mar 2026 was -$188.1 million, a 34.45% decrease from a year earlier, with the FY2025 full-year figure at -$191.7 million, down 62.4% from the prior year.
  • Free Cash Flow climbed to -$46.5 million in Q1 2026 per ANNX's latest filing, from -$51.1 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$21.7 million in Q2 2024 and bottomed at -$52.4 million in Q3 2025.
  • The 5-year median for Free Cash Flow is -$33.0 million (2023), against an average of -$35.0 million.
  • Across the five-year window, Free Cash Flow jumped 40.59% in 2024 and slumped 75.44% in 2025, its largest moves.
  • Year by year, Free Cash Flow stood at -$27.1 million in 2022, then increased by 13.44% to -$23.5 million in 2023, then tumbled by 53.39% to -$36.0 million in 2024, then sank by 41.86% to -$51.1 million in 2025, then climbed by 8.96% to -$46.5 million in 2026.
  • Per Business Quant, the three latest ANNX Free Cash Flow figures stand at -$46.5 million (Q1 2026), -$51.1 million (Q4 2025), and -$52.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Annexon 1.03 Bn 804.24 Mn - -46.52 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -46.52 Mn
Mar 31, 2026 -46.52 Mn
Dec 31, 2025 -51.10 Mn
Dec 31, 2025 -51.10 Mn
Sep 30, 2025 -52.35 Mn
Sep 30, 2025 -52.35 Mn
Jun 30, 2025 -38.09 Mn
Jun 30, 2025 -38.09 Mn
Mar 31, 2025 -50.13 Mn
Mar 31, 2025 -50.13 Mn
Dec 31, 2024 -36.02 Mn
Dec 31, 2024 -36.02 Mn
Sep 30, 2024 -32.02 Mn
Sep 30, 2024 -32.02 Mn
Jun 30, 2024 -21.71 Mn
Jun 30, 2024 -21.71 Mn
Mar 31, 2024 -28.63 Mn
Mar 31, 2024 -28.63 Mn
Dec 31, 2023 -23.48 Mn
Dec 31, 2023 -23.48 Mn