Anaptysbio (ANAB) Operating Income (2016 - 2026)

Anaptysbio's (ANAB) quarterly Operating Income came in at -$34.6 million in Q1 2026, down 25.77% YoY from -$46.7 million in Q1 2025, and down 151.77% on a QoQ basis from $66.9 million in Q4 2025.

Anaptysbio (ANAB) Operating Income (2016 - 2026) Analysis & Trends

Anaptysbio (ANAB) has 11 years of Operating Income data on file, last reported at -$34.6 million in Q1 2026.

  • Quarterly Operating Income fell 25.77% year-over-year to -$34.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $40.8 million (up 140.68% YoY) and the FY2025 annual result came in at $47.9 million, up 141.67% from the prior year.
  • Operating Income declined to -$34.6 million in Q1 2026, from $66.9 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $66.9 million in Q4 2025 to a low of -$44.4 million in Q1 2023.
  • A 5-year average of -$22.4 million and a median of -$29.6 million in 2022 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2022 — Operating Income tumbled 5115.57% — and 2025, when it soared 791.84%.
  • Tracing ANAB's Operating Income over 5 years: stood at -$26.0 million in 2022, then tumbled by 62.23% to -$42.1 million in 2023, then surged by 77.05% to -$9.7 million in 2024, then jumped by 791.84% to $66.9 million in 2025, then plunged by 151.77% to -$34.6 million in 2026.
  • The last three Operating Income figures came in at -$34.6 million (Q1 2026), $66.9 million (Q4 2025), and $34.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Anaptysbio 1.70 Bn 1.41 Bn - -34.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -34.64 Mn
Dec 31, 2025 66.90 Mn
Sep 30, 2025 34.70 Mn
Jun 30, 2025 -26.17 Mn
Mar 31, 2025 -27.54 Mn
Dec 31, 2024 -9.67 Mn
Sep 30, 2024 -22.76 Mn
Jun 30, 2024 -40.32 Mn
Mar 31, 2024 -42.20 Mn
Dec 31, 2023 -42.14 Mn
Sep 30, 2023 -37.73 Mn
Jun 30, 2023 -40.14 Mn
Mar 31, 2023 -44.40 Mn
Dec 31, 2022 -25.97 Mn
Sep 30, 2022 -29.63 Mn
Jun 30, 2022 -27.80 Mn
Mar 31, 2022 -31.75 Mn
Dec 31, 2021 -31.16 Mn
Sep 30, 2021 -6.76 Mn
Jun 30, 2021 -533,000.00