Anaptysbio (ANAB) EBITDA (2016 - 2026)

Anaptysbio (ANAB) posted EBITDA of -$34.6 million for Q1 2026, down 151.77% on a QoQ basis from $66.9 million in Q4 2025, and down 25.77% year-over-year from -$46.7 million in Q1 2025.

Anaptysbio (ANAB) EBITDA (2016 - 2026) Analysis & Trends

Anaptysbio's EBITDA history runs 11 years deep, the most recent figure standing at -$34.6 million for Q1 2026.

  • Quarterly EBITDA fell 25.77% year-over-year to -$34.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $40.8 million (up 140.68% YoY) and the FY2025 annual result came in at $47.9 million, up 141.67% from the prior year.
  • EBITDA was -$34.6 million for Q1 2026 at Anaptysbio, down from $66.9 million in the prior quarter.
  • Across five years, EBITDA topped out at $66.9 million in Q4 2025 and bottomed at -$44.4 million in Q1 2023.
  • A 5-year average of -$22.4 million and a median of -$29.6 million in 2022 frame the typical range for EBITDA.
  • Annual changes were most pronounced in 2022 — EBITDA slumped 5115.57% — and 2025, when it soared 791.84%.
  • Anaptysbio's EBITDA stood at -$26.0 million in 2022, then sank by 62.23% to -$42.1 million in 2023, then jumped by 77.05% to -$9.7 million in 2024, then soared by 791.84% to $66.9 million in 2025, then slumped by 151.77% to -$34.6 million in 2026.
  • Business Quant data shows ANAB's EBITDA at -$34.6 million in Q1 2026, $66.9 million in Q4 2025, and $34.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Anaptysbio 1.55 Bn 1.27 Bn - -34.64 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -34.64 Mn
Dec 31, 2025 66.90 Mn
Sep 30, 2025 34.70 Mn
Jun 30, 2025 -26.17 Mn
Mar 31, 2025 -27.54 Mn
Dec 31, 2024 -9.67 Mn
Sep 30, 2024 -22.76 Mn
Jun 30, 2024 -40.32 Mn
Mar 31, 2024 -42.20 Mn
Dec 31, 2023 -42.14 Mn
Sep 30, 2023 -37.73 Mn
Jun 30, 2023 -40.14 Mn
Mar 31, 2023 -44.40 Mn
Dec 31, 2022 -25.97 Mn
Sep 30, 2022 -29.63 Mn
Jun 30, 2022 -27.80 Mn
Mar 31, 2022 -31.75 Mn
Dec 31, 2021 -31.16 Mn
Sep 30, 2021 -6.76 Mn
Jun 30, 2021 -533,000.00