Amylyx Pharmaceuticals (AMLX) Return on Equity [ROE] (2022 - 2026)
Amylyx Pharmaceuticals' Return on Equity [ROE] was -59.32% in Q2 2026, up 42.28 percentage points from -101.60% a year earlier but down 7.44 percentage points from the prior quarter.
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Analysis
Amylyx Pharmaceuticals (AMLX) Return on Equity [ROE] (2022 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Amylyx Pharmaceuticals came in at -61.59%, up 39.30 percentage points from FY2024.
- Return on Equity [ROE] shows a three-year change of +147.85 percentage points (FY2022 to FY2025).
- In earlier years, Return on Equity [ROE] was -100.88% in FY2024 (-113.62 pp), 12.73% in FY2023 (+222.17 pp) and -209.43% in FY2022.
- Quarterly Return on Equity [ROE] has moved between -270.12% (Q1 2022) and 11.57% (Q4 2023) over five years.
- Compared with a year earlier, Return on Equity [ROE] has increased for four straight quarters, with an average year-over-year change of -19.12 percentage points over the last eight quarters.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q1 2023 (a gain of 227.15 percentage points); the worst was Q4 2024 (a drop of 178.75 percentage points).
- Per Business Quant data, AMLX's Return on Equity [ROE] in the three quarters before Q2 2026 was -51.88% (Q1 2026), -45.42% (Q4 2025) and -59.73% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Amylyx Pharmaceuticals | 3.24 Bn | 3.24 Bn | - | -59.32% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -59.32% |
| Mar 31, 2026 | -51.88% |
| Dec 31, 2025 | -45.42% |
| Sep 30, 2025 | -59.73% |
| Jun 30, 2025 | -101.60% |
| Mar 31, 2025 | -119.53% |
| Dec 31, 2024 | -167.19% |
| Sep 30, 2024 | -113.42% |
| Jun 30, 2024 | -56.64% |
| Mar 31, 2024 | -18.76% |
| Dec 31, 2023 | 11.57% |
| Sep 30, 2023 | 0.46% |
| Jun 30, 2023 | -19.70% |
| Mar 31, 2023 | -42.98% |
| Dec 31, 2022 | -81.87% |
| Sep 30, 2022 | -109.28% |
| Jun 30, 2022 | -70.75% |
| Mar 31, 2022 | -270.12% |
API Access
Amylyx Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=AMLX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "AMLX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=AMLX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();