Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026)

Amylyx Pharmaceuticals' (AMLX) quarterly Return on Capital Employed came in at 53.6% in Q1 2026, up 6849.0% year-on-year from 0.77% in Q1 2025, and down 13.63% quarter-over-quarter from 47.17% in Q4 2025.

Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026) Analysis & Trends

Amylyx Pharmaceuticals' Return on Capital Employed history runs 5 years deep, the most recent figure standing at 53.6% for Q1 2026.

  • On a quarterly basis, Return on Capital Employed rose 6849.0% year-over-year to 53.6% in Q1 2026; TTM through Mar 2026 was 53.6%, a 6849.0% increase from a year earlier, with the FY2025 full-year figure at 63.75%, up 3246.0% from the prior year.
  • Return on Capital Employed fell to 53.6% in Q1 2026 per AMLX's latest filing, from 47.17% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 9.46% in Q4 2023 and bottomed at 162.43% in Q4 2024.
  • The 5-year median for Return on Capital Employed is 62.22% (2025), against an average of 67.12%.
  • Across the five-year window, Return on Capital Employed plunged 17189 bps in 2024 and surged 11526 bps in 2025, its largest moves.
  • Year by year, Return on Capital Employed stood at 83.95% in 2022, then soared by 111 bps to 9.46% in 2023, then plunged by 1816 bps to 162.43% in 2024, then jumped by 71 bps to 47.17% in 2025, then dropped by 14 bps to 53.6% in 2026.
  • Per Business Quant, the three latest AMLX Return on Capital Employed figures stand at 53.6% (Q1 2026), 47.17% (Q4 2025), and 62.22% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 8.52%
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 27.36%
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn -1.50%
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 21.43%
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn 0.46%
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 20.04%
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 5.24%
10 Amylyx Pharmaceuticals 1.94 Bn 1.94 Bn - -53.60%

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.60%
Dec 31, 2025 -47.17%
Sep 30, 2025 -62.22%
Jun 30, 2025 -106.06%
Mar 31, 2025 -122.09%
Dec 31, 2024 -162.43%
Sep 30, 2024 -114.58%
Jun 30, 2024 -58.33%
Mar 31, 2024 -21.63%
Dec 31, 2023 9.46%
Sep 30, 2023 -1.86%
Jun 30, 2023 -22.12%
Mar 31, 2023 -44.70%
Dec 31, 2022 -83.95%
Sep 30, 2022 -108.42%
Jun 30, 2022 -68.84%
Mar 31, 2022 -72.47%