Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026)
Amylyx Pharmaceuticals (AMLX) recorded quarterly Return on Capital Employed of 12.24% in Q1 2026, down 30.88% quarter-over-quarter from 9.35% in Q4 2025, and down 2330.0% on a YoY basis from 0.55% in Q1 2025.
Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026) Analysis & Trends
Amylyx Pharmaceuticals' Return on Capital Employed history runs 5 years deep, the most recent figure standing at 12.24% for Q1 2026.
- In Q1 2026, Return on Capital Employed fell 2330.0% year-over-year to 12.24%; the TTM figure through Mar 2026 stood at 12.24% (down 2330.0% YoY), while the FY2025 annual figure was 12.64%, up 676.0% from the prior year.
- Return on Capital Employed was 12.24% for Q1 2026 at Amylyx Pharmaceuticals, down from 9.35% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 37.15% in Q3 2025 to a low of 114.58% in Q3 2024.
- Historically, Return on Capital Employed has averaged 33.19% across 5 years, with a median of 22.12% in 2023.
- The sharpest annual moves came in 2024 and 2025: Return on Capital Employed sank 11271 bps in 2024, then soared 15172 bps in 2025.
- A 5-year view of Return on Capital Employed shows it stood at 83.95% in 2022, then soared by 111 bps to 9.46% in 2023, then tumbled by 446 bps to 32.74% in 2024, then soared by 71 bps to 9.35% in 2025, then sank by 31 bps to 12.24% in 2026.
- The last three Return on Capital Employed figures came in at 12.24% (Q1 2026), 9.35% (Q4 2025), and 37.15% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Teva Pharmaceutical Industries | 39.72 Bn | 35.98 Bn | 1.97 Bn | 8.52% |
| 2 | Zoetis | 34.61 Bn | 32.67 Bn | 1.62 Bn | 27.58% |
| 3 | United Therapeutics | 24.07 Bn | 21.91 Bn | 648.10 Mn | 21.43% |
| 4 | Aurora Cannabis | 16.98 Bn | 16.91 Bn | 33.43 Mn | - |
| 5 | Neurocrine Biosciences | 16.64 Bn | 15.32 Bn | 800.70 Mn | 20.04% |
| 6 | Elanco Animal Health | 12.19 Bn | 11.76 Bn | 785.00 Mn | 7.34% |
| 7 | Alkermes | 7.37 Bn | 6.86 Bn | -116.06 Mn | 6.92% |
| 8 | Hims & Hers Health | 6.62 Bn | 5.87 Bn | 396.79 Mn | -1.92% |
| 9 | Lantheus Holdings | 6.47 Bn | 5.97 Bn | 230.92 Mn | 14.85% |
| 10 | Amylyx Pharmaceuticals | 1.51 Bn | 1.51 Bn | - | -12.24% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -12.24% |
| Dec 31, 2025 | -9.35% |
| Sep 30, 2025 | 37.15% |
| Jun 30, 2025 | 29.24% |
| Mar 31, 2025 | 11.06% |
| Dec 31, 2024 | -32.74% |
| Sep 30, 2024 | -114.58% |
| Jun 30, 2024 | -58.33% |
| Mar 31, 2024 | -21.63% |
| Dec 31, 2023 | 9.46% |
| Sep 30, 2023 | -1.86% |
| Jun 30, 2023 | -22.12% |
| Mar 31, 2023 | -44.70% |
| Dec 31, 2022 | -83.95% |
| Sep 30, 2022 | -108.42% |
| Jun 30, 2022 | -68.84% |
| Mar 31, 2022 | -72.47% |