Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026)

Amylyx Pharmaceuticals (AMLX) recorded quarterly Return on Capital Employed of 12.24% in Q1 2026, down 30.88% quarter-over-quarter from 9.35% in Q4 2025, and down 2330.0% on a YoY basis from 0.55% in Q1 2025.

Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026) Analysis & Trends

Amylyx Pharmaceuticals' Return on Capital Employed history runs 5 years deep, the most recent figure standing at 12.24% for Q1 2026.

  • In Q1 2026, Return on Capital Employed fell 2330.0% year-over-year to 12.24%; the TTM figure through Mar 2026 stood at 12.24% (down 2330.0% YoY), while the FY2025 annual figure was 12.64%, up 676.0% from the prior year.
  • Return on Capital Employed was 12.24% for Q1 2026 at Amylyx Pharmaceuticals, down from 9.35% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 37.15% in Q3 2025 to a low of 114.58% in Q3 2024.
  • Historically, Return on Capital Employed has averaged 33.19% across 5 years, with a median of 22.12% in 2023.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed sank 11271 bps in 2024, then soared 15172 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 83.95% in 2022, then soared by 111 bps to 9.46% in 2023, then tumbled by 446 bps to 32.74% in 2024, then soared by 71 bps to 9.35% in 2025, then sank by 31 bps to 12.24% in 2026.
  • The last three Return on Capital Employed figures came in at 12.24% (Q1 2026), 9.35% (Q4 2025), and 37.15% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn 8.52%
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn 27.58%
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn 21.43%
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn -
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn 20.04%
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn 7.34%
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn 6.92%
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -1.92%
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn 14.85%
10 Amylyx Pharmaceuticals 1.51 Bn 1.51 Bn - -12.24%

Historic Data

Download Data
DateValue
Mar 31, 2026 -12.24%
Dec 31, 2025 -9.35%
Sep 30, 2025 37.15%
Jun 30, 2025 29.24%
Mar 31, 2025 11.06%
Dec 31, 2024 -32.74%
Sep 30, 2024 -114.58%
Jun 30, 2024 -58.33%
Mar 31, 2024 -21.63%
Dec 31, 2023 9.46%
Sep 30, 2023 -1.86%
Jun 30, 2023 -22.12%
Mar 31, 2023 -44.70%
Dec 31, 2022 -83.95%
Sep 30, 2022 -108.42%
Jun 30, 2022 -68.84%
Mar 31, 2022 -72.47%