Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026)
Amylyx Pharmaceuticals' (AMLX) quarterly Return on Capital Employed came in at 53.6% in Q1 2026, up 6849.0% year-on-year from 0.77% in Q1 2025, and down 13.63% quarter-over-quarter from 47.17% in Q4 2025.
Amylyx Pharmaceuticals (AMLX) Return on Capital Employed (2022 - 2026) Analysis & Trends
Amylyx Pharmaceuticals' Return on Capital Employed history runs 5 years deep, the most recent figure standing at 53.6% for Q1 2026.
- On a quarterly basis, Return on Capital Employed rose 6849.0% year-over-year to 53.6% in Q1 2026; TTM through Mar 2026 was 53.6%, a 6849.0% increase from a year earlier, with the FY2025 full-year figure at 63.75%, up 3246.0% from the prior year.
- Return on Capital Employed fell to 53.6% in Q1 2026 per AMLX's latest filing, from 47.17% in the prior quarter.
- Across five years, Return on Capital Employed topped out at 9.46% in Q4 2023 and bottomed at 162.43% in Q4 2024.
- The 5-year median for Return on Capital Employed is 62.22% (2025), against an average of 67.12%.
- Across the five-year window, Return on Capital Employed plunged 17189 bps in 2024 and surged 11526 bps in 2025, its largest moves.
- Year by year, Return on Capital Employed stood at 83.95% in 2022, then soared by 111 bps to 9.46% in 2023, then plunged by 1816 bps to 162.43% in 2024, then jumped by 71 bps to 47.17% in 2025, then dropped by 14 bps to 53.6% in 2026.
- Per Business Quant, the three latest AMLX Return on Capital Employed figures stand at 53.6% (Q1 2026), 47.17% (Q4 2025), and 62.22% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Haleon | 87.22 Bn | 85.35 Bn | - | - |
| 2 | Teva Pharmaceutical Industries | 39.60 Bn | 35.87 Bn | 1.97 Bn | 8.52% |
| 3 | Zoetis | 31.46 Bn | 29.52 Bn | 1.62 Bn | 27.36% |
| 4 | Takeda Pharmaceutical | 26.49 Bn | 22.44 Bn | 4.39 Bn | -1.50% |
| 5 | United Therapeutics | 23.03 Bn | 20.88 Bn | 648.10 Mn | 21.43% |
| 6 | Universe Pharmaceuticals | 23.03 Bn | -10.56 Bn | - | - |
| 7 | Viatris | 20.90 Bn | 19.09 Bn | 1.16 Bn | 0.46% |
| 8 | Neurocrine Biosciences | 17.50 Bn | 16.19 Bn | 800.70 Mn | 20.04% |
| 9 | Elanco Animal Health | 12.33 Bn | 11.91 Bn | 785.00 Mn | 5.24% |
| 10 | Amylyx Pharmaceuticals | 1.94 Bn | 1.94 Bn | - | -53.60% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -53.60% |
| Dec 31, 2025 | -47.17% |
| Sep 30, 2025 | -62.22% |
| Jun 30, 2025 | -106.06% |
| Mar 31, 2025 | -122.09% |
| Dec 31, 2024 | -162.43% |
| Sep 30, 2024 | -114.58% |
| Jun 30, 2024 | -58.33% |
| Mar 31, 2024 | -21.63% |
| Dec 31, 2023 | 9.46% |
| Sep 30, 2023 | -1.86% |
| Jun 30, 2023 | -22.12% |
| Mar 31, 2023 | -44.70% |
| Dec 31, 2022 | -83.95% |
| Sep 30, 2022 | -108.42% |
| Jun 30, 2022 | -68.84% |
| Mar 31, 2022 | -72.47% |