Amylyx Pharmaceuticals AMLX Institutional Ownership

NASDAQ AMLX

$29.11 -0.17 (-0.58%)

As of: Sep 30, 2026 · 3:59 PM EDT

Institutions by Trading Activity

206 Institutions

Increased 122 59.2%

Unchanged 24 11.7%

Reduced 60 29.1%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

104.04%

▲+0.80 pp QoQ

Shares Held by Institutions

115.69Mn

of 111.20Mn outstanding

▲+6.34% QoQ

Shares Outstanding

111.20Mn

-4.49Mn held outside 13F filers

Institutional Investors

206

filed 13F for Jun 2026

▲+35 vs prior quarter

Net Shares Added (QoQ)

+6.90Mn

accumulated since last quarter

Value of Holdings

$3.39Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Amylyx Pharmaceuticals, Inc. (NASDAQ:AMLX) has 206 institutional investors that have filed 13F reports for the period ending June 2026.

Their combined ownership stood at 104.0% of outstanding shares in June 2026, up from 103.2% in March 2026.
Their total shares held in AMLX increased 6.34% from the prior quarter, while the number of investors in Amylyx Pharmaceuticals increased 60.94% year over year.
Activity in AMLX broke down as 122 buyers, 60 sellers, and 24 unchanged among 206 total holders.
Combined, these investors held 115.69Mn shares in AMLX for June 2026, up by 6.9Mn shares quarter on quarter, and up 35.95Mn shares year over year.
FMR LLC holds the largest position in AMLX at 16.73Mn shares as of June 30, 2026, or 15.04% of shares outstanding.
The biggest buyers of Amylyx Pharmaceuticals for the quarter ending June 2026 included Jupiter Topco LLC (5.24Mn), Jpmorgan Chase & Co (1.7Mn), Alyeska Investment Group, L.P. (1.05Mn), Morgan Stanley (955.26K), Aberdeen Group plc (737.67K).
Top sellers of AMLX stock for the quarter ending June 2026 included ADAGE CAPITAL PARTNERS GP, L.L.C. (1.66Mn), Almitas Capital LLC (1.15Mn), GREAT POINT PARTNERS LLC (1.05Mn), Barclays Plc (915.6K), DEUTSCHE BANK AG\ (709.85K).
Per Business Quant data, the top 10 holders of Amylyx Pharmaceuticals for the quarter ending June 2026 are FMR LLC (16.73Mn), BlackRock, Inc. (8.83Mn), PERCEPTIVE ADVISORS LLC (8.33Mn), TCG Crossover Management, LLC (6.24Mn), Commodore Capital LP (5.65Mn), Jupiter Topco LLC (5.24Mn), Saturn V Capital Management LP (4.62Mn), VANGUARD CAPITAL MANAGEMENT LLC (4.22Mn), Morgan Stanley (3.13Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (3.04Mn).

Form 13F Holdings

206 Institutional Holders

Report period 30 Jun, 2026

Total shares held 115.69Mn

Of outstanding 104.04%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	16,727,909	15.04%	▲97,368	+0.59%	$300.43Mn
2	BlackRock, Inc.	0002012383	8,827,085	7.94%	▼1,751	-0.02%	$158.53Mn
3	PERCEPTIVE ADVISORS LLC	0001224962	8,334,882	7.50%	▲50,000	+0.60%	$149.69Mn
4	TCG Crossover Management, LLC	0001839948	6,243,812	5.62%	0	0.00%	$112.14Mn
5	Commodore Capital LP	0001831942	5,650,000	5.08%	0	0.00%	$101.47Mn
6	Jupiter Topco LLC	0002146052	5,236,102	4.71%	▲5,236,102	0.00%	$94.01Mn
7	Saturn V Capital Management LP	0001964437	4,624,101	4.16%	▲274,216	+6.30%	$83.05Mn
8	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	4,224,224	3.80%	▲82,649	+2.00%	$75.87Mn
9	Morgan Stanley	0000895421	3,130,808	2.82%	▲955,261	+43.91%	$56.23Mn
10	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	3,036,970	2.73%	▲49,823	+1.67%	$54.54Mn
11	First Light Asset Management, LLC	0001600004	3,023,256	2.72%	▼167,389	-5.25%	$54.30Mn
12	Franklin Templeton Inc	0000038777	2,950,225	2.65%	▲688,656	+30.45%	$52.99Mn
13	Goldman Sachs Group Inc	0000886982	2,858,239	2.57%	▲232,248	+8.84%	$51.33Mn
14	State Street Corp	0000093751	2,603,337	2.34%	▲240,176	+10.16%	$46.76Mn
15	GEODE CAPITAL MANAGEMENT, LLC	0001214717	2,335,315	2.10%	▲124,383	+5.63%	$41.95Mn
16	ADAGE CAPITAL PARTNERS GP, L.L.C.	0001165408	1,900,000	1.71%	▼1,660,764	-46.64%	$34.12Mn
17	Jpmorgan Chase & Co	0000019617	1,863,650	1.68%	▲1,703,987	+1,067.24%	$34.92Mn
18	Siren, L.L.C.	0002005245	1,480,586	1.33%	▲250,586	+20.37%	$26.59Mn
19	EVENTIDE ASSET MANAGEMENT, LLC	0001442891	1,327,536	1.19%	▼186,422	-12.31%	$23.84Mn
20	683 Capital Management, LLC	0001404574	1,279,512	1.15%	▼250,488	-16.37%	$22.98Mn

Showing 1 to 20 of 206 holders