Amylyx Pharmaceuticals AMLX Institutional Ownership

NASDAQ AMLX

$33.27 -0.61 (-1.80%)

As of: Sep 9, 2026 · 10:35 AM EDT

Institutions by Trading Activity

206 Institutions

Increased 122 59.2%

Unchanged 24 11.7%

Reduced 60 29.1%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

104.04%

▼-3.71 pp QoQ

Shares Held by Institutions

115.69Mn

of 111.20Mn outstanding

▲+6.34% QoQ

Shares Outstanding

111.20Mn

-4.49Mn held outside 13F filers

Institutional Investors

206

filed 13F for Jun 2026

▲+35 vs prior quarter

Net Shares Added (QoQ)

+6.90Mn

accumulated since last quarter

Value of Holdings

$3.95Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Amylyx Pharmaceuticals, Inc. (NASDAQ:AMLX) appears in 206 institutional 13F filings for the quarter ending June 2026.

Their combined ownership stood at 104.0% of outstanding shares in June 2026, down from 107.8% in March 2026.
They increased total shares held in Amylyx Pharmaceuticals by 6.34% from last quarter, and the number of investors in AMLX increased 60.94% annually.
During the quarter, 122 of these 206 funds increased positions in AMLX, 60 reduced exposure, and 24 held steady.
The aggregate institutional position in Amylyx Pharmaceuticals amounted to 115.69Mn shares as of June 2026, up by 6.9Mn shares quarter on quarter, and up 34.38Mn shares year over year.
FMR LLC is the top holder of Amylyx Pharmaceuticals as of June 30, 2026, with 16.73Mn shares representing 15.04% of outstanding stock.
The most significant purchases of AMLX for the quarter ending June 2026 came from Jupiter Topco LLC (5.24Mn), Jpmorgan Chase & Co (1.7Mn), Alyeska Investment Group, L.P. (1.05Mn), Morgan Stanley (955.26K), Aberdeen Group plc (737.67K).
Top sellers of AMLX stock for the quarter ending June 2026 included ADAGE CAPITAL PARTNERS GP, L.L.C. (1.66Mn), Almitas Capital LLC (1.15Mn), GREAT POINT PARTNERS LLC (1.05Mn), Barclays Plc (915.6K), DEUTSCHE BANK AG\ (709.85K).
Amylyx Pharmaceuticals's 10 largest shareholders as of June 2026 include FMR LLC (16.73Mn), BlackRock, Inc. (8.83Mn), PERCEPTIVE ADVISORS LLC (8.33Mn), TCG Crossover Management, LLC (6.24Mn), Commodore Capital LP (5.65Mn), Jupiter Topco LLC (5.24Mn), Saturn V Capital Management LP (4.62Mn), VANGUARD CAPITAL MANAGEMENT LLC (4.22Mn), Morgan Stanley (3.13Mn), DRIEHAUS CAPITAL MANAGEMENT LLC (3.04Mn) per Business Quant data.

Form 13F Holdings

206 Institutional Holders

Report period 30 Jun, 2026

Total shares held 115.69Mn

Of outstanding 104.04%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	16,727,909	15.04%	▲97,368	+0.59%	$300.43Mn
2	BlackRock, Inc.	0002012383	8,827,085	7.94%	▼1,751	-0.02%	$158.53Mn
3	PERCEPTIVE ADVISORS LLC	0001224962	8,334,882	7.50%	▲50,000	+0.60%	$149.69Mn
4	TCG Crossover Management, LLC	0001839948	6,243,812	5.62%	0	0.00%	$112.14Mn
5	Commodore Capital LP	0001831942	5,650,000	5.08%	0	0.00%	$101.47Mn
6	Jupiter Topco LLC	0002146052	5,236,102	4.71%	▲5,236,102	0.00%	$94.01Mn
7	Saturn V Capital Management LP	0001964437	4,624,101	4.16%	▲274,216	+6.30%	$83.05Mn
8	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	4,224,224	3.80%	▲82,649	+2.00%	$75.87Mn
9	Morgan Stanley	0000895421	3,130,808	2.82%	▲955,261	+43.91%	$56.23Mn
10	DRIEHAUS CAPITAL MANAGEMENT LLC	0000938206	3,036,970	2.73%	▲49,823	+1.67%	$54.54Mn
11	First Light Asset Management, LLC	0001600004	3,023,256	2.72%	▼167,389	-5.25%	$54.30Mn
12	Franklin Resources Inc	0000038777	2,950,225	2.65%	▲688,656	+30.45%	$52.99Mn
13	Goldman Sachs Group Inc	0000886982	2,858,239	2.57%	▲232,248	+8.84%	$51.33Mn
14	State Street Corp	0000093751	2,603,337	2.34%	▲240,176	+10.16%	$46.76Mn
15	GEODE CAPITAL MANAGEMENT, LLC	0001214717	2,335,315	2.10%	▲124,383	+5.63%	$41.95Mn
16	ADAGE CAPITAL PARTNERS GP, L.L.C.	0001165408	1,900,000	1.71%	▼1,660,764	-46.64%	$34.12Mn
17	Jpmorgan Chase & Co	0000019617	1,863,650	1.68%	▲1,703,987	+1,067.24%	$34.92Mn
18	Siren, L.L.C.	0002005245	1,480,586	1.33%	▲250,586	+20.37%	$26.59Mn
19	EVENTIDE ASSET MANAGEMENT, LLC	0001442891	1,327,536	1.19%	▼186,422	-12.31%	$23.84Mn
20	683 Capital Management, LLC	0001404574	1,279,512	1.15%	▼250,488	-16.37%	$22.98Mn

Showing 1 to 20 of 206 holders