Amylyx Pharmaceuticals (AMLX) Return on Assets [ROA] (2022 - 2026)
Amylyx Pharmaceuticals (AMLX) recorded Return on Assets [ROA] of -54.45% in Q2 2026, up 36.12 percentage points from -90.57% a year earlier but down 6.53 percentage points from the prior quarter.
Amylyx Pharmaceuticals (AMLX) Return on Assets [ROA] (2022 - 2026) Analysis & Trends
For FY2025, Amylyx Pharmaceuticals reported Return on Assets [ROA] of -55.00%, up 29.86 percentage points from FY2024.
- Annual Return on Assets [ROA] has a three-year change of +24.82 percentage points (FY2022 to FY2025).
- Across earlier years, Return on Assets [ROA] came in at -84.87% in FY2024 (-95.71 pp), 10.84% in FY2023 (+90.66 pp) and -79.82% in FY2022.
- Quarterly Return on Assets [ROA] has ranged from -135.81% in Q4 2024 to 10.01% in Q4 2023 over the past five years.
- On a year-over-year basis, Return on Assets [ROA] has increased for four consecutive quarters, with an average year-over-year change of -18.56 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Assets [ROA] in the last five years was a gain of 94.19 percentage points in Q4 2025, against a drop of 145.83 percentage points in Q4 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -47.92% (Q1 2026), -41.63% (Q4 2025) and -53.57% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 10.47% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 4.65% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 2.45% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 28.37% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 9.10% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 9.29% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -6.13% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 2.14% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 16.34% |
| 10 | Amylyx Pharmaceuticals | 3.24 Bn | 3.24 Bn | - | -54.45% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -54.45% |
| Mar 31, 2026 | -47.92% |
| Dec 31, 2025 | -41.63% |
| Sep 30, 2025 | -53.57% |
| Jun 30, 2025 | -90.57% |
| Mar 31, 2025 | -105.90% |
| Dec 31, 2024 | -135.81% |
| Sep 30, 2024 | -89.03% |
| Jun 30, 2024 | -44.25% |
| Mar 31, 2024 | -15.21% |
| Dec 31, 2023 | 10.01% |
| Sep 30, 2023 | 0.40% |
| Jun 30, 2023 | -16.90% |
| Mar 31, 2023 | -37.27% |
| Dec 31, 2022 | -69.26% |
| Sep 30, 2022 | -90.51% |
| Jun 30, 2022 | -61.41% |
| Mar 31, 2022 | -63.81% |
Amylyx Pharmaceuticals Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=AMLX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "AMLX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=AMLX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();