Amylyx Pharmaceuticals AMLX
NASDAQ AMLX
$33.16 -0.72 (-2.13%)
As of: Sep 9, 2026 · 11:59 AM EDT

Amylyx Pharmaceuticals (AMLX) Operating Income (2021 - 2026)

Amylyx Pharmaceuticals (AMLX) posted Operating Income of -$45.7 million for Q2 2026, down 4.37% on a QoQ basis from -$43.8 million in Q1 2026, and down 6.62% year-over-year from -$48.9 million in Q2 2025.

Analysis

Amylyx Pharmaceuticals (AMLX) Operating Income (2021 - 2026) Analysis & Trends

Amylyx Pharmaceuticals has reported Operating Income for 6 years, with the latest figure at -$45.7 million in Q2 2026.

  • On a quarterly basis, Operating Income fell 6.62% year-over-year to -$45.7 million in Q2 2026; TTM through Jun 2026 was -$162.1 million, a 17.7% increase from a year earlier, with the FY2025 full-year figure at -$153.3 million, up 51.29% from the prior year.
  • Operating Income was -$45.7 million for Q2 2026 at Amylyx Pharmaceuticals, down from -$43.8 million in the prior quarter.
  • The five-year high for Operating Income was $20.2 million in Q2 2023, with the low at -$122.1 million in Q1 2024.
  • Average Operating Income over 5 years is -$40.0 million, with a median of -$43.3 million recorded in 2025.
  • The sharpest annual moves came in 2023 and 2024: Operating Income surged 137.23% in 2023, then slumped 5848.86% in 2024.
  • Over 5 years, Operating Income stood at -$44.6 million in 2022, then soared by 104.34% to $1.9 million in 2023, then sank by 2202.07% to -$40.7 million in 2024, then increased by 9.96% to -$36.6 million in 2025, then decreased by 24.83% to -$45.7 million in 2026.
  • The last three Operating Income figures came in at -$45.7 million (Q2 2026), -$43.8 million (Q1 2026), and -$36.6 million (Q4 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Amgen 212.20 Bn 198.21 Bn 7.24 Bn 3.51 Bn
2 Gilead Sciences 181.83 Bn 178.65 Bn 6.22 Bn -10.39 Bn
3 Vertex Pharmaceuticals 132.47 Bn 124.61 Bn 2.84 Bn 1.25 Bn
4 Regeneron Pharmaceuticals 82.56 Bn 74.56 Bn 3.93 Bn 1.29 Bn
5 Argenx Se 61.59 Bn 56.40 Bn 1.37 Bn 493.00 Mn
6 Moderna 54.65 Bn 49.51 Bn 52.00 Mn -815.00 Mn
7 Alnylam Pharmaceuticals 34.13 Bn 30.82 Bn 992.69 Mn 231.44 Mn
8 Biogen 31.42 Bn 30.13 Bn 1.96 Bn -644.50 Mn
9 Roivant Sciences 30.21 Bn 30.21 Bn 1.16 Mn -365.99 Mn
10 Amylyx Pharmaceuticals 3.68 Bn 3.68 Bn - -45.69 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -45.69 Mn
Mar 31, 2026 -43.78 Mn
Dec 31, 2025 -36.61 Mn
Sep 30, 2025 -36.03 Mn
Jun 30, 2025 -42.86 Mn
Mar 31, 2025 -37.80 Mn
Dec 31, 2024 -40.65 Mn
Sep 30, 2024 -75.66 Mn
Jun 30, 2024 -76.29 Mn
Mar 31, 2024 -122.13 Mn
Dec 31, 2023 1.93 Mn
Sep 30, 2023 18.72 Mn
Jun 30, 2023 20.20 Mn
Mar 31, 2023 -2.05 Mn
Dec 31, 2022 -44.59 Mn
Sep 30, 2022 -54.68 Mn
Jun 30, 2022 -54.25 Mn
Mar 31, 2022 -47.81 Mn
Dec 31, 2021 -28.32 Mn
Sep 30, 2021 -22.92 Mn