Amylyx Pharmaceuticals (AMLX) EBITDA (2021 - 2026)

Amylyx Pharmaceuticals' (AMLX) quarterly EBITDA came in at -$43.8 million in Q1 2026, down 15.81% year-on-year from -$52.0 million in Q1 2025, and down 19.6% quarter-over-quarter from -$36.6 million in Q4 2025.

Amylyx Pharmaceuticals (AMLX) EBITDA (2021 - 2026) Analysis & Trends

Amylyx Pharmaceuticals' EBITDA history runs 6 years deep, the most recent figure standing at -$43.8 million for Q1 2026.

  • On a quarterly basis, EBITDA fell 15.81% year-over-year to -$43.8 million in Q1 2026; TTM through Mar 2026 was -$159.3 million, a 30.87% increase from a year earlier, with the FY2025 full-year figure at -$153.3 million, up 51.29% from the prior year.
  • EBITDA slipped to -$43.8 million in Q1 2026 per AMLX's latest filing, from -$36.6 million in the prior quarter.
  • Across five years, EBITDA topped out at $20.2 million in Q2 2023 and bottomed at -$122.1 million in Q1 2024.
  • The 5-year median for EBITDA is -$42.9 million (2025), against an average of -$39.7 million.
  • Across the five-year window, EBITDA soared 137.23% in 2023 and tumbled 5848.86% in 2024, its largest moves.
  • Year by year, EBITDA stood at -$44.6 million in 2022, then surged by 104.34% to $1.9 million in 2023, then plunged by 2202.07% to -$40.7 million in 2024, then grew by 9.96% to -$36.6 million in 2025, then declined by 19.6% to -$43.8 million in 2026.
  • Per Business Quant, the three latest AMLX EBITDA figures stand at -$43.8 million (Q1 2026), -$36.6 million (Q4 2025), and -$36.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 652.00 Mn
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 833.00 Mn
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn -2.65 Bn
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 325.80 Mn
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn -79.70 Mn
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 193.40 Mn
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 291.00 Mn
10 Amylyx Pharmaceuticals 1.94 Bn 1.94 Bn - -43.78 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -43.78 Mn
Dec 31, 2025 -36.61 Mn
Sep 30, 2025 -36.03 Mn
Jun 30, 2025 -42.86 Mn
Mar 31, 2025 -37.80 Mn
Dec 31, 2024 -40.65 Mn
Sep 30, 2024 -75.66 Mn
Jun 30, 2024 -76.29 Mn
Mar 31, 2024 -122.13 Mn
Dec 31, 2023 1.93 Mn
Sep 30, 2023 18.72 Mn
Jun 30, 2023 20.20 Mn
Mar 31, 2023 -2.05 Mn
Dec 31, 2022 -44.59 Mn
Sep 30, 2022 -54.68 Mn
Jun 30, 2022 -54.25 Mn
Mar 31, 2022 -47.81 Mn
Dec 31, 2021 -28.32 Mn
Sep 30, 2021 -22.92 Mn
Jun 30, 2021 -18.59 Mn