Amylyx Pharmaceuticals (AMLX) EBITDA (2021 - 2026)
Amylyx Pharmaceuticals' (AMLX) quarterly EBITDA came in at -$43.8 million in Q1 2026, down 15.81% year-on-year from -$52.0 million in Q1 2025, and down 19.6% quarter-over-quarter from -$36.6 million in Q4 2025.
Amylyx Pharmaceuticals (AMLX) EBITDA (2021 - 2026) Analysis & Trends
Amylyx Pharmaceuticals' EBITDA history runs 6 years deep, the most recent figure standing at -$43.8 million for Q1 2026.
- On a quarterly basis, EBITDA fell 15.81% year-over-year to -$43.8 million in Q1 2026; TTM through Mar 2026 was -$159.3 million, a 30.87% increase from a year earlier, with the FY2025 full-year figure at -$153.3 million, up 51.29% from the prior year.
- EBITDA slipped to -$43.8 million in Q1 2026 per AMLX's latest filing, from -$36.6 million in the prior quarter.
- Across five years, EBITDA topped out at $20.2 million in Q2 2023 and bottomed at -$122.1 million in Q1 2024.
- The 5-year median for EBITDA is -$42.9 million (2025), against an average of -$39.7 million.
- Across the five-year window, EBITDA soared 137.23% in 2023 and tumbled 5848.86% in 2024, its largest moves.
- Year by year, EBITDA stood at -$44.6 million in 2022, then surged by 104.34% to $1.9 million in 2023, then plunged by 2202.07% to -$40.7 million in 2024, then grew by 9.96% to -$36.6 million in 2025, then declined by 19.6% to -$43.8 million in 2026.
- Per Business Quant, the three latest AMLX EBITDA figures stand at -$43.8 million (Q1 2026), -$36.6 million (Q4 2025), and -$36.0 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Haleon | 87.22 Bn | 85.35 Bn | - | - |
| 2 | Teva Pharmaceutical Industries | 39.60 Bn | 35.87 Bn | 1.97 Bn | 652.00 Mn |
| 3 | Zoetis | 31.46 Bn | 29.52 Bn | 1.62 Bn | 833.00 Mn |
| 4 | Takeda Pharmaceutical | 26.49 Bn | 22.44 Bn | 4.39 Bn | -2.65 Bn |
| 5 | United Therapeutics | 23.03 Bn | 20.88 Bn | 648.10 Mn | 325.80 Mn |
| 6 | Universe Pharmaceuticals | 23.03 Bn | -10.56 Bn | - | - |
| 7 | Viatris | 20.90 Bn | 19.09 Bn | 1.16 Bn | -79.70 Mn |
| 8 | Neurocrine Biosciences | 17.50 Bn | 16.19 Bn | 800.70 Mn | 193.40 Mn |
| 9 | Elanco Animal Health | 12.33 Bn | 11.91 Bn | 785.00 Mn | 291.00 Mn |
| 10 | Amylyx Pharmaceuticals | 1.94 Bn | 1.94 Bn | - | -43.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -43.78 Mn |
| Dec 31, 2025 | -36.61 Mn |
| Sep 30, 2025 | -36.03 Mn |
| Jun 30, 2025 | -42.86 Mn |
| Mar 31, 2025 | -37.80 Mn |
| Dec 31, 2024 | -40.65 Mn |
| Sep 30, 2024 | -75.66 Mn |
| Jun 30, 2024 | -76.29 Mn |
| Mar 31, 2024 | -122.13 Mn |
| Dec 31, 2023 | 1.93 Mn |
| Sep 30, 2023 | 18.72 Mn |
| Jun 30, 2023 | 20.20 Mn |
| Mar 31, 2023 | -2.05 Mn |
| Dec 31, 2022 | -44.59 Mn |
| Sep 30, 2022 | -54.68 Mn |
| Jun 30, 2022 | -54.25 Mn |
| Mar 31, 2022 | -47.81 Mn |
| Dec 31, 2021 | -28.32 Mn |
| Sep 30, 2021 | -22.92 Mn |
| Jun 30, 2021 | -18.59 Mn |