Altimmune (ALT) EBITDA Margin (2010 - 2025)

Altimmune (ALT) posted quarterly EBITDA Margin of 111126.92% for Q4 2025, up 38619308.0% year-over-year from N/an in Q4 2024, and up 73.36% quarter-over-quarter from 417180.0% in Q3 2025.

Altimmune (ALT) EBITDA Margin (2010 - 2025) Analysis & Trends

Altimmune (ALT) has reported EBITDA Margin for 16 consecutive years, with 111126.92% the latest figure, recorded in Q4 2025.

  • In Q4 2025, EBITDA Margin rose 38619308.0% year-over-year to 111126.92%; the TTM figure through Dec 2025 stood at 230460.98% (up 28539902.0% YoY), while the FY2025 annual figure was 230460.98%, up 28539902.0% from the prior year.
  • EBITDA Margin rose to 111126.92% in Q4 2025 per ALT's latest filing, from 417180.0% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 731.92% in Q4 2021 and bottomed at 1237600.0% in Q3 2022.
  • Historically, EBITDA Margin has averaged 283564.09% across 5 years, with a median of 183032.21% in 2025.
  • Annual changes were most pronounced in 2022 — EBITDA Margin sank 121658481 bps — and 2023, when it soared 123137348 bps.
  • Altimmune's EBITDA Margin stood at 731.92% in 2021, then tumbled by 12036 bps to 88823.08% in 2022, then slipped by 2 bps to 90872.97% in 2023, then plunged by 447 bps to 497320.0% in 2024, then surged by 78 bps to 111126.92% in 2025.
  • Business Quant data shows ALT's EBITDA Margin at 111126.92% in Q4 2025, 417180.0% in Q3 2025, and 458440.0% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.15%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 31.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 19.06%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,569,866.34%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.75%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 17.93%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.36%
10 Altimmune 571.75 Mn 571.75 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -111,126.92%
Sep 30, 2025 -417,180.00%
Jun 30, 2025 -458,440.00%
Mar 31, 2025 -436,300.00%
Dec 31, 2024 -497,320.00%
Sep 30, 2024 -495,340.00%
Jun 30, 2024 -534,900.00%
Mar 31, 2024 -535,880.00%
Dec 31, 2023 -90,872.97%
Sep 30, 2023 -6,226.52%
Jun 30, 2023 -300,116.67%
Mar 31, 2023 -103,614.29%
Dec 31, 2022 -88,823.08%
Sep 30, 2022 -1,237,600.00%
Jun 30, 2022 -254,937.50%
Mar 31, 2022 -60,934.38%
Dec 31, 2021 -731.92%
Sep 30, 2021 -21,015.19%
Jun 30, 2021 -18,148.91%
Mar 31, 2021 -1,773.39%