Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026)
Alnylam Pharmaceuticals (ALNY) reported Gross Profit of $959.7 million for Q1 2026, up 2488.21% on a YoY basis from $37.1 million in Q1 2025, and up 15.72% quarter-over-quarter from $829.3 million in Q4 2025.
Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026) Analysis & Trends
Alnylam Pharmaceuticals has reported Gross Profit for 9 years, with the latest figure at $959.7 million in Q1 2026.
- For the quarter ending Q1 2026, Gross Profit rose 2488.21% year-over-year to $959.7 million; the trailing twelve-month figure through Mar 2026 stood at $3.5 billion (up 137.54% YoY), and the FY2025 full-year result was $3.0 billion, up 56.4% from the prior year.
- Gross Profit for Q1 2026 stood at $959.7 million, up from $829.3 million in the prior quarter.
- The five-year high for Gross Profit was $1.1 billion in Q3 2025, with the low at -$40.2 million in Q1 2025.
- Historically, Gross Profit has averaged $460.7 million across 5 years, with a median of $418.9 million in 2024.
- Annual changes were most pronounced in 2025 — Gross Profit slumped 109.14% — and 2026, when it jumped 2488.21%.
- Alnylam Pharmaceuticals' Gross Profit stood at $288.9 million in 2022, then rose by 27.31% to $367.7 million in 2023, then surged by 33.39% to $490.5 million in 2024, then jumped by 69.07% to $829.3 million in 2025, then increased by 15.72% to $959.7 million in 2026.
- The last three Gross Profit figures came in at $959.7 million (Q1 2026), $829.3 million (Q4 2025), and $1.1 billion (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Alnylam Pharmaceuticals | 37.04 Bn | 34.03 Bn | 959.66 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 959.66 Mn |
| Mar 31, 2026 | 959.66 Mn |
| Dec 31, 2025 | 829.31 Mn |
| Dec 31, 2025 | 829.31 Mn |
| Sep 30, 2025 | 1.05 Bn |
| Sep 30, 2025 | 1.05 Bn |
| Jun 30, 2025 | 631.66 Mn |
| Jun 30, 2025 | 631.66 Mn |
| Mar 31, 2025 | -40.18 Mn |
| Mar 31, 2025 | -40.18 Mn |
| Dec 31, 2024 | 490.52 Mn |
| Dec 31, 2024 | 490.52 Mn |
| Sep 30, 2024 | 418.94 Mn |
| Sep 30, 2024 | 418.94 Mn |
| Jun 30, 2024 | 592.55 Mn |
| Jun 30, 2024 | 592.55 Mn |
| Mar 31, 2024 | 439.72 Mn |
| Mar 31, 2024 | 439.72 Mn |
| Dec 31, 2023 | 367.74 Mn |
| Dec 31, 2023 | 367.74 Mn |