Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026)

Alnylam Pharmaceuticals (ALNY) posted Gross Profit of $959.7 million for Q1 2026, up 15.72% on a QoQ basis from $829.3 million in Q4 2025, and up 83.14% year-over-year from $524.0 million in Q1 2025.

Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' Gross Profit history runs 9 years deep, the most recent figure standing at $959.7 million for Q1 2026.

  • Quarterly Gross Profit rose 83.14% year-over-year to $959.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $3.5 billion (up 71.39% YoY) and the FY2025 annual result came in at $3.0 billion, up 56.4% from the prior year.
  • Gross Profit was $959.7 million for Q1 2026 at Alnylam Pharmaceuticals, up from $829.3 million in the prior quarter.
  • Across five years, Gross Profit topped out at $1.1 billion in Q3 2025 and bottomed at $189.8 million in Q1 2022.
  • A 5-year average of $493.9 million and a median of $439.7 million in 2024 frame the typical range for Gross Profit.
  • Annual changes were most pronounced in 2023 — Gross Profit soared 194.58% — and 2024, when it sank 37.57%.
  • Alnylam Pharmaceuticals' Gross Profit stood at $288.9 million in 2022, then advanced by 27.31% to $367.7 million in 2023, then jumped by 33.39% to $490.5 million in 2024, then soared by 69.07% to $829.3 million in 2025, then gained by 15.72% to $959.7 million in 2026.
  • Business Quant data shows ALNY's Gross Profit at $959.7 million in Q1 2026, $829.3 million in Q4 2025, and $1.1 billion in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn
4 NuCana 279.75 Bn 279.75 Bn -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn
7 Belite Bio 62.51 Bn 62.51 Bn -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn -
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 959.66 Mn
Mar 31, 2026 959.66 Mn
Dec 31, 2025 829.31 Mn
Dec 31, 2025 829.31 Mn
Sep 30, 2025 1.05 Bn
Sep 30, 2025 1.05 Bn
Jun 30, 2025 631.66 Mn
Jun 30, 2025 631.66 Mn
Mar 31, 2025 524.01 Mn
Mar 31, 2025 524.01 Mn
Dec 31, 2024 490.52 Mn
Dec 31, 2024 490.52 Mn
Sep 30, 2024 418.94 Mn
Sep 30, 2024 418.94 Mn
Jun 30, 2024 592.55 Mn
Jun 30, 2024 592.55 Mn
Mar 31, 2024 439.72 Mn
Mar 31, 2024 439.72 Mn
Dec 31, 2023 367.74 Mn
Dec 31, 2023 367.74 Mn