Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026)

Alnylam Pharmaceuticals (ALNY) reported Gross Profit of $959.7 million for Q1 2026, up 2488.21% on a YoY basis from $37.1 million in Q1 2025, and up 15.72% quarter-over-quarter from $829.3 million in Q4 2025.

Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026) Analysis & Trends

Alnylam Pharmaceuticals has reported Gross Profit for 9 years, with the latest figure at $959.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Gross Profit rose 2488.21% year-over-year to $959.7 million; the trailing twelve-month figure through Mar 2026 stood at $3.5 billion (up 137.54% YoY), and the FY2025 full-year result was $3.0 billion, up 56.4% from the prior year.
  • Gross Profit for Q1 2026 stood at $959.7 million, up from $829.3 million in the prior quarter.
  • The five-year high for Gross Profit was $1.1 billion in Q3 2025, with the low at -$40.2 million in Q1 2025.
  • Historically, Gross Profit has averaged $460.7 million across 5 years, with a median of $418.9 million in 2024.
  • Annual changes were most pronounced in 2025 — Gross Profit slumped 109.14% — and 2026, when it jumped 2488.21%.
  • Alnylam Pharmaceuticals' Gross Profit stood at $288.9 million in 2022, then rose by 27.31% to $367.7 million in 2023, then surged by 33.39% to $490.5 million in 2024, then jumped by 69.07% to $829.3 million in 2025, then increased by 15.72% to $959.7 million in 2026.
  • The last three Gross Profit figures came in at $959.7 million (Q1 2026), $829.3 million (Q4 2025), and $1.1 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Alnylam Pharmaceuticals 37.04 Bn 34.03 Bn 959.66 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 959.66 Mn
Mar 31, 2026 959.66 Mn
Dec 31, 2025 829.31 Mn
Dec 31, 2025 829.31 Mn
Sep 30, 2025 1.05 Bn
Sep 30, 2025 1.05 Bn
Jun 30, 2025 631.66 Mn
Jun 30, 2025 631.66 Mn
Mar 31, 2025 -40.18 Mn
Mar 31, 2025 -40.18 Mn
Dec 31, 2024 490.52 Mn
Dec 31, 2024 490.52 Mn
Sep 30, 2024 418.94 Mn
Sep 30, 2024 418.94 Mn
Jun 30, 2024 592.55 Mn
Jun 30, 2024 592.55 Mn
Mar 31, 2024 439.72 Mn
Mar 31, 2024 439.72 Mn
Dec 31, 2023 367.74 Mn
Dec 31, 2023 367.74 Mn