Growth Metrics

Alnylam Pharmaceuticals (ALNY) Gross Profit (2018 - 2026)

Alnylam Pharmaceuticals posted quarterly Gross Profit of $959.7 million for Q1 2026, up 2488.21% year-on-year from $37.1 million in Q1 2025, and up 15.72% on a QoQ basis from $829.3 million in Q4 2025.

Alnylam Pharmaceuticals (ALNY) has 9 years of Gross Profit data on file, last reported at $959.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Gross Profit rose 2488.21% year-over-year to $959.7 million; the trailing twelve-month figure through Mar 2026 stood at $3.5 billion (up 137.54% YoY), and the FY2025 full-year result was $3.0 billion, up 56.4% from the prior year.
  • Gross Profit for Q1 2026 stood at $959.7 million, up from $829.3 million in the prior quarter.
  • Across five years, Gross Profit topped out at $1.1 billion in Q3 2025 and bottomed at -$40.2 million in Q1 2025.
  • The 5-year median for Gross Profit is $418.9 million (2024), against an average of $460.7 million.
  • The widest annual swing landed in 2025, when Gross Profit plunged 109.14%; it then jumped 2488.21% in 2026.
  • A 5-year view of Gross Profit shows it stood at $288.9 million in 2022, then gained by 27.31% to $367.7 million in 2023, then soared by 33.39% to $490.5 million in 2024, then surged by 69.07% to $829.3 million in 2025, then rose by 15.72% to $959.7 million in 2026.
  • The last three Gross Profit figures came in at $959.7 million (Q1 2026), $829.3 million (Q4 2025), and $1.1 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Revolution Medicines 32.39 Bn 32.39 Bn -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 959.66 Mn
Mar 31, 2026 959.66 Mn
Dec 31, 2025 829.31 Mn
Dec 31, 2025 829.31 Mn
Sep 30, 2025 1.05 Bn
Sep 30, 2025 1.05 Bn
Jun 30, 2025 631.66 Mn
Jun 30, 2025 631.66 Mn
Mar 31, 2025 -40.18 Mn
Mar 31, 2025 -40.18 Mn
Dec 31, 2024 490.52 Mn
Dec 31, 2024 490.52 Mn
Sep 30, 2024 418.94 Mn
Sep 30, 2024 418.94 Mn
Jun 30, 2024 592.55 Mn
Jun 30, 2024 592.55 Mn
Mar 31, 2024 439.72 Mn
Mar 31, 2024 439.72 Mn
Dec 31, 2023 367.74 Mn
Dec 31, 2023 367.74 Mn
Sep 30, 2023 671.06 Mn
Sep 30, 2023 671.06 Mn
Jun 30, 2023 243.42 Mn
Jun 30, 2023 243.42 Mn
Mar 31, 2023 277.86 Mn
Mar 31, 2023 277.86 Mn
Dec 31, 2022 288.86 Mn
Dec 31, 2022 288.86 Mn
Sep 30, 2022 227.80 Mn
Sep 30, 2022 227.80 Mn
Jun 30, 2022 190.78 Mn
Jun 30, 2022 190.78 Mn
Mar 31, 2022 189.80 Mn
Mar 31, 2022 189.80 Mn
Dec 31, 2021 224.90 Mn
Dec 31, 2021 224.90 Mn
Sep 30, 2021 159.54 Mn
Sep 30, 2021 159.54 Mn
Jun 30, 2021 190.30 Mn
Jun 30, 2021 190.30 Mn
Mar 31, 2021 154.54 Mn
Mar 31, 2021 154.54 Mn
Dec 31, 2020 141.77 Mn
Dec 31, 2020 141.77 Mn
Sep 30, 2020 105.03 Mn
Sep 30, 2020 105.03 Mn
Jun 30, 2020 85.70 Mn
Jun 30, 2020 85.70 Mn
Mar 31, 2020 86.17 Mn
Mar 31, 2020 86.17 Mn
Dec 31, 2019 59.51 Mn
Dec 31, 2019 59.51 Mn
Sep 30, 2019 64.85 Mn
Sep 30, 2019 64.85 Mn
Jun 30, 2019 40.39 Mn
Jun 30, 2019 40.39 Mn
Mar 31, 2019 29.95 Mn
Mar 31, 2019 29.95 Mn
Dec 31, 2018 19.37 Mn
Dec 31, 2018 19.37 Mn
Sep 30, 2018 1.93 Mn
Sep 30, 2018 1.93 Mn