Alumis (ALMS) Operating Income (2023 - 2025)
Alumis' (ALMS) quarterly Operating Income came in at -$96.4 million in Q4 2025, up 2.21% year-on-year from -$94.4 million in Q4 2024, and up 16.35% on a QoQ basis from -$115.3 million in Q3 2025.
Alumis (ALMS) Operating Income (2023 - 2025) Analysis & Trends
Alumis (ALMS) has 3 years of Operating Income data on file, last reported at -$96.4 million in Q4 2025.
- On a quarterly basis, Operating Income rose 2.21% year-over-year to -$96.4 million in Q4 2025; TTM through Dec 2025 was -$453.8 million, a 50.89% decrease from a year earlier, with the FY2025 full-year figure at -$453.8 million, down 50.89% from the prior year.
- Operating Income for Q4 2025 stood at -$96.4 million, up from -$115.3 million in the prior quarter.
- Over the last five years, Operating Income for ALMS reached as high as -$37.6 million in Q2 2023 and fell as low as -$140.5 million in Q2 2025.
- Historically, Operating Income has averaged -$79.6 million across 3 years, with a median of -$96.4 million in 2025.
- On a YoY basis, Operating Income climbed as much as 2.21% in 2025 and fell as far as 150.34% in 2025.
- Year by year, Operating Income stood at -$40.1 million in 2023, then sank by 145.74% to -$98.6 million in 2024, then climbed by 2.21% to -$96.4 million in 2025.
- Per Business Quant data, the three most recent Operating Income figures were -$96.4 million in Q4 2025, -$115.3 million in Q3 2025, and -$140.5 million in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Alumis | 2.37 Bn | 2.06 Bn | - | -96.45 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -96.45 Mn |
| Sep 30, 2025 | -115.29 Mn |
| Jun 30, 2025 | -140.54 Mn |
| Mar 31, 2025 | -101.53 Mn |
| Dec 31, 2024 | -98.62 Mn |
| Sep 30, 2024 | -98.40 Mn |
| Jun 30, 2024 | -56.14 Mn |
| Mar 31, 2024 | -47.59 Mn |
| Dec 31, 2023 | -40.13 Mn |
| Sep 30, 2023 | -43.76 Mn |
| Jun 30, 2023 | -37.62 Mn |