Alumis (ALMS) EBITDA (2023 - 2026)
Alumis (ALMS) posted quarterly EBITDA of -$96.4 million for Q4 2025, up 2.21% year-over-year from -$94.4 million in Q4 2024, and up 16.35% quarter-over-quarter from -$115.3 million in Q3 2025.
Alumis (ALMS) EBITDA (2023 - 2026) Analysis & Trends
Alumis (ALMS) has reported EBITDA for 3 consecutive years, with -$96.4 million the latest figure, recorded in Q4 2025.
- In Q4 2025, EBITDA rose 2.21% year-over-year to -$96.4 million; the TTM figure through Dec 2025 stood at -$453.8 million (down 50.89% YoY), while the FY2025 annual figure was -$453.8 million, down 50.89% from the prior year.
- EBITDA climbed to -$96.4 million in Q4 2025 per ALMS's latest filing, from -$115.3 million in the prior quarter.
- Across five years, EBITDA topped out at -$37.6 million in Q2 2023 and bottomed at -$140.5 million in Q2 2025.
- Historically, EBITDA has averaged -$79.6 million across 3 years, with a median of -$96.4 million in 2025.
- On a YoY basis, EBITDA climbed as much as 2.21% in 2025 and fell as far as 150.34% in 2025.
- Alumis' EBITDA stood at -$40.1 million in 2023, then sank by 145.74% to -$98.6 million in 2024, then gained by 2.21% to -$96.4 million in 2025.
- Business Quant data shows ALMS's EBITDA at -$96.4 million in Q4 2025, -$115.3 million in Q3 2025, and -$140.5 million in Q2 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 493.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 325.05 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2.33 Bn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 133.12 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 231.44 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Alumis | 3.25 Bn | 2.75 Bn | - | -148.86 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -148.86 Mn |
| Dec 31, 2025 | -96.45 Mn |
| Sep 30, 2025 | -115.29 Mn |
| Jun 30, 2025 | -140.54 Mn |
| Mar 31, 2025 | -101.53 Mn |
| Dec 31, 2024 | -98.62 Mn |
| Sep 30, 2024 | -98.40 Mn |
| Jun 30, 2024 | -56.14 Mn |
| Mar 31, 2024 | -47.59 Mn |
| Dec 31, 2023 | -40.13 Mn |
| Sep 30, 2023 | -43.76 Mn |
| Jun 30, 2023 | -37.62 Mn |