Alumis (ALMS) EBITDA (2023 - 2025)

Alumis (ALMS) reported EBITDA of -$93.0 million for Q4 2025, up 1.98% year-over-year from -$91.2 million in Q4 2024, and up 15.89% quarter-over-quarter from -$110.5 million in Q3 2025.

Alumis (ALMS) EBITDA (2023 - 2025) Analysis & Trends

Alumis (ALMS) has 3 years of EBITDA data on file, last reported at -$93.0 million in Q4 2025.

  • EBITDA for Q4 2025 came in at -$93.0 million, up 1.98% year-over-year; the trailing twelve-month figure through Dec 2025 was -$243.2 million (up 17.34% YoY), and the FY2025 annual result was -$243.2 million, up 17.34% from the prior year.
  • EBITDA advanced to -$93.0 million in Q4 2025 per ALMS's latest filing, from -$110.5 million in the prior quarter.
  • Over five years, EBITDA peaked at $59.4 million in Q2 2025 and troughed at -$110.5 million in Q3 2025.
  • A 3-year average of -$59.7 million and a median of -$56.5 million in 2024 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2024 and 2025: EBITDA sank 141.38% in 2024, then surged 205.03% in 2025.
  • A 3-year view of EBITDA shows it stood at -$39.3 million in 2023, then slumped by 141.38% to -$94.9 million in 2024, then rose by 1.98% to -$93.0 million in 2025.
  • Business Quant data shows ALMS's EBITDA at -$93.0 million in Q4 2025, -$110.5 million in Q3 2025, and $59.4 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Alumis 1.99 Bn 1.90 Bn - -92.98 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -92.98 Mn
Sep 30, 2025 -110.54 Mn
Jun 30, 2025 59.35 Mn
Mar 31, 2025 -99.01 Mn
Dec 31, 2024 -94.86 Mn
Sep 30, 2024 -92.98 Mn
Jun 30, 2024 -56.51 Mn
Mar 31, 2024 -49.85 Mn
Dec 31, 2023 -39.30 Mn
Sep 30, 2023 -43.38 Mn
Jun 30, 2023 -36.26 Mn