Agios Pharmaceuticals (AGIO) Operating Income (2012 - 2026)
Agios Pharmaceuticals (AGIO) posted Operating Income of -$110.0 million for Q1 2026, up 9.5% on a QoQ basis from -$121.6 million in Q4 2025, and down 3.18% year-over-year from -$113.6 million in Q1 2025.
Agios Pharmaceuticals (AGIO) Operating Income (2012 - 2026) Analysis & Trends
Agios Pharmaceuticals' Operating Income history runs 15 years deep, the most recent figure standing at -$110.0 million for Q1 2026.
- Quarterly Operating Income fell 3.18% year-over-year to -$110.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$475.5 million (down 8.0% YoY) and the FY2025 annual result came in at -$472.1 million, down 10.9% from the prior year.
- Operating Income was -$110.0 million for Q1 2026 at Agios Pharmaceuticals, up from -$121.6 million in the prior quarter.
- Across five years, Operating Income topped out at -$90.6 million in Q1 2023 and bottomed at -$127.1 million in Q2 2025.
- A 5-year average of -$105.2 million and a median of -$102.8 million in 2024 frame the typical range for Operating Income.
- Annual changes were most pronounced in 2023 — Operating Income rose 10.41% — and 2025, when it declined 20.07%.
- Agios Pharmaceuticals' Operating Income stood at -$99.2 million in 2022, then fell by 7.16% to -$106.3 million in 2023, then declined by 17.65% to -$125.0 million in 2024, then grew by 2.77% to -$121.6 million in 2025, then increased by 9.5% to -$110.0 million in 2026.
- Business Quant data shows AGIO's Operating Income at -$110.0 million in Q1 2026, -$121.6 million in Q4 2025, and -$116.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Agios Pharmaceuticals | 2.13 Bn | 2.13 Bn | 19.43 Mn | -110.03 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -110.03 Mn |
| Dec 31, 2025 | -121.58 Mn |
| Sep 30, 2025 | -116.87 Mn |
| Jun 30, 2025 | -127.06 Mn |
| Mar 31, 2025 | -106.63 Mn |
| Dec 31, 2024 | -125.04 Mn |
| Sep 30, 2024 | -102.81 Mn |
| Jun 30, 2024 | -105.82 Mn |
| Mar 31, 2024 | -92.07 Mn |
| Dec 31, 2023 | -106.28 Mn |
| Sep 30, 2023 | -100.90 Mn |
| Jun 30, 2023 | -93.70 Mn |
| Mar 31, 2023 | -90.61 Mn |
| Dec 31, 2022 | -99.17 Mn |
| Sep 30, 2022 | -91.09 Mn |
| Jun 30, 2022 | -97.64 Mn |
| Mar 31, 2022 | -101.15 Mn |
| Dec 31, 2021 | -104.83 Mn |
| Sep 30, 2021 | -91.15 Mn |
| Jun 30, 2021 | -91.22 Mn |