Agios Pharmaceuticals (AGIO) Net Margin (2012 - 2026)
Agios Pharmaceuticals (AGIO) reported Net Margin of -225.06% for Q2 2026, up 674.34 percentage points from -899.40% a year earlier and up 252.68 percentage points from the prior quarter.
Agios Pharmaceuticals (AGIO) Net Margin (2012 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Agios Pharmaceuticals' Net Margin came in at -418.24%, down 2008.65 percentage points year-over-year; for FY2025, it was -764.01%, down 2609.94 percentage points from FY2024.
- Net Margin has a three-year change of +863.80 percentage points (FY2022 to FY2025).
- By year, Net Margin came in at 1845.92% in FY2024 (+3158.56 pp), -1312.63% in FY2023 (+315.18 pp) and -1627.82% in FY2022.
- The Q2 2026 figure ranks as the highest quarterly Net Margin since Q3 2024.
- Year over year, Net Margin has now increased in each of the last three quarters, with an average year-over-year change of +331.20 percentage points over the last eight quarters.
- The high point for year-over-year Net Margin in five years was Q3 2024 (a gain of 11808.96 percentage points); the low point was Q3 2025 (a drop of 11377.74 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -477.74% (Q1 2026), -541.09% (Q4 2025) and -803.05% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,264.65 Bn | 1,238.27 Bn | 20.46 Bn | 26.44% |
| 2 | Johnson & Johnson | 677.74 Bn | 597.60 Bn | 17.30 Bn | 0.83% |
| 3 | AbbVie | 517.10 Bn | 485.11 Bn | 13.12 Bn | 24.24% |
| 4 | Merck | 362.23 Bn | 325.17 Bn | 13.19 Bn | 28.01% |
| 5 | Novartis Ag | 315.90 Bn | 276.16 Bn | 11.24 Bn | 22.65% |
| 6 | Astrazeneca | 289.40 Bn | 266.24 Bn | 12.86 Bn | 16.30% |
| 7 | Amgen | 249.90 Bn | 201.56 Bn | 7.58 Bn | 37.28% |
| 8 | Gilead Sciences | 209.15 Bn | 184.26 Bn | 6.73 Bn | 29.27% |
| 9 | Pfizer | 165.88 Bn | 113.23 Bn | 12.56 Bn | 19.55% |
| 10 | Agios Pharmaceuticals | 1.88 Bn | -959.14 Mn | 52.86 Mn | -117.44% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -117.44% |
| Jun 30, 2026 | -225.06% |
| Mar 31, 2026 | -477.74% |
| Dec 31, 2025 | -541.09% |
| Sep 30, 2025 | -803.05% |
| Jun 30, 2025 | -899.40% |
| Mar 31, 2025 | -1,023.25% |
| Dec 31, 2024 | -899.56% |
| Sep 30, 2024 | 10,574.69% |
| Jun 30, 2024 | -1,115.71% |
| Mar 31, 2024 | -995.84% |
| Dec 31, 2023 | -1,350.70% |
| Sep 30, 2023 | -1,234.27% |
| Jun 30, 2023 | -1,248.60% |
| Mar 31, 2023 | -1,444.43% |
| Dec 31, 2022 | 847.47% |
| Sep 30, 2022 | -2,325.00% |
| Jun 30, 2022 | -1,644.68% |
| Mar 31, 2022 | -11,391.11% |
| Dec 31, 2020 | -221.72% |
Agios Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "AGIO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();