Agios Pharmaceuticals (AGIO) Net Margin (2012 - 2026)
Agios Pharmaceuticals (AGIO) reported Net Margin of -225.06% for Q2 2026, up 674.34 percentage points from -899.40% a year earlier and up 252.68 percentage points from the prior quarter.
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Analysis
Agios Pharmaceuticals (AGIO) Net Margin (2012 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Agios Pharmaceuticals' Net Margin came in at -418.24%, down 2008.65 percentage points year-over-year; for FY2025, it was -764.01%, down 2609.94 percentage points from FY2024.
- Net Margin has a three-year change of +863.80 percentage points (FY2022 to FY2025).
- By year, Net Margin came in at 1845.92% in FY2024 (+3158.56 pp), -1312.63% in FY2023 (+315.18 pp) and -1627.82% in FY2022.
- The Q2 2026 figure ranks as the highest quarterly Net Margin since Q3 2024.
- Year over year, Net Margin has now increased in each of the last three quarters, with an average year-over-year change of +331.20 percentage points over the last eight quarters.
- The high point for year-over-year Net Margin in five years was Q3 2024 (a gain of 11808.96 percentage points); the low point was Q3 2025 (a drop of 11377.74 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -477.74% (Q1 2026), -541.09% (Q4 2025) and -803.05% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Agios Pharmaceuticals | 1.99 Bn | 1.99 Bn | 41.75 Mn | -225.06% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -225.06% |
| Mar 31, 2026 | -477.74% |
| Dec 31, 2025 | -541.09% |
| Sep 30, 2025 | -803.05% |
| Jun 30, 2025 | -899.40% |
| Mar 31, 2025 | -1,023.25% |
| Dec 31, 2024 | -899.56% |
| Sep 30, 2024 | 10,574.69% |
| Jun 30, 2024 | -1,115.71% |
| Mar 31, 2024 | -995.84% |
| Dec 31, 2023 | -1,350.70% |
| Sep 30, 2023 | -1,234.27% |
| Jun 30, 2023 | -1,248.60% |
| Mar 31, 2023 | -1,444.43% |
| Dec 31, 2022 | 847.47% |
| Sep 30, 2022 | -2,325.00% |
| Jun 30, 2022 | -1,644.68% |
| Mar 31, 2022 | -11,391.11% |
| Dec 31, 2020 | -221.72% |
| Sep 30, 2020 | -285.19% |
API Access
Agios Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "AGIO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();