Agios Pharmaceuticals (AGIO) EBT Margin (2012 - 2026)
Agios Pharmaceuticals' EBT Margin came in at -247.07% for Q2 2026, up 773.05 percentage points from -1020.12% a year earlier and up 283.27 percentage points from the prior quarter.
Agios Pharmaceuticals (AGIO) EBT Margin (2012 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Agios Pharmaceuticals reported EBT Margin of -440.38%, down 2059.84 percentage points year-over-year; for FY2025, it was -765.89%, down 2733.04 percentage points from FY2024.
- EBT Margin carries a three-year change of +861.92 percentage points (FY2022 to FY2025).
- Going back by year, EBT Margin was 1967.15% in FY2024 (+3279.78 pp), -1312.63% in FY2023 (+315.18 pp) and -1627.82% in FY2022.
- The Q2 2026 figure represents the highest quarterly EBT Margin since Q3 2024.
- Year-over-year, EBT Margin has increased for three consecutive quarters, with an average year-over-year change of +351.37 percentage points over the last eight quarters.
- The fastest year-over-year change in EBT Margin over five years came in Q3 2024 (a gain of 12401.56 percentage points), and the weakest in Q3 2025 (a drop of 11970.33 percentage points).
- Business Quant data shows AGIO's EBT Margin at -530.34% (Q1 2026), -546.18% (Q4 2025) and -803.05% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 26.66% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 25.18% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -4.11% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 29.63% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.19% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 27.53% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -131.41% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -4.34% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 41.75% |
| 10 | Agios Pharmaceuticals | 1.99 Bn | 1.99 Bn | 41.75 Mn | -247.07% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -247.07% |
| Mar 31, 2026 | -530.34% |
| Dec 31, 2025 | -546.18% |
| Sep 30, 2025 | -803.05% |
| Jun 30, 2025 | -1,020.12% |
| Mar 31, 2025 | -1,221.97% |
| Dec 31, 2024 | -982.28% |
| Sep 30, 2024 | 11,167.28% |
| Jun 30, 2024 | -1,228.29% |
| Mar 31, 2024 | -1,124.34% |
| Dec 31, 2023 | -1,350.70% |
| Sep 30, 2023 | -1,234.27% |
| Jun 30, 2023 | -1,273.03% |
| Mar 31, 2023 | -1,471.24% |
| Dec 31, 2022 | -2,150.44% |
| Sep 30, 2022 | -2,482.14% |
| Jun 30, 2022 | -1,717.07% |
| Mar 31, 2022 | -12,073.44% |
| Dec 31, 2020 | -191.94% |
| Sep 30, 2020 | -228.13% |
Agios Pharmaceuticals EBT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebt-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebt-margin", "ticker": "AGIO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebt-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();