Agios Pharmaceuticals (AGIO) EBT (2012 - 2026)

Agios Pharmaceuticals (AGIO) posted EBT of -$147.8 million for Q1 2026, down 35.49% on a QoQ basis from -$109.1 million in Q4 2025, and down 32.56% year-over-year from -$219.1 million in Q1 2025.

Agios Pharmaceuticals (AGIO) EBT (2012 - 2026) Analysis & Trends

Agios Pharmaceuticals' EBT history runs 15 years deep, the most recent figure standing at -$147.8 million for Q1 2026.

  • Quarterly EBT fell 32.56% year-over-year to -$147.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$492.2 million (down 173.06% YoY) and the FY2025 annual result came in at -$413.8 million, down 157.63% from the prior year.
  • EBT was -$147.8 million for Q1 2026 at Agios Pharmaceuticals, down from -$109.1 million in the prior quarter.
  • Across five years, EBT topped out at $1.0 billion in Q3 2024 and bottomed at -$147.8 million in Q1 2026.
  • A 5-year average of -$39.6 million and a median of -$100.3 million in 2022 frame the typical range for EBT.
  • Annual changes were most pronounced in 2024 — EBT surged 1196.14% — and 2025, when it tumbled 110.33%.
  • Agios Pharmaceuticals' EBT stood at -$97.1 million in 2022, then rose by 1.2% to -$95.9 million in 2023, then declined by 9.86% to -$105.4 million in 2024, then decreased by 3.47% to -$109.1 million in 2025, then sank by 35.49% to -$147.8 million in 2026.
  • Business Quant data shows AGIO's EBT at -$147.8 million in Q1 2026, -$109.1 million in Q4 2025, and -$103.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.97 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 259.22 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.49 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 541.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Agios Pharmaceuticals 2.13 Bn 2.13 Bn 19.43 Mn -147.76 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -147.76 Mn
Dec 31, 2025 -109.06 Mn
Sep 30, 2025 -103.43 Mn
Jun 30, 2025 -131.97 Mn
Mar 31, 2025 -111.47 Mn
Dec 31, 2024 -105.40 Mn
Sep 30, 2024 1.00 Bn
Jun 30, 2024 -110.50 Mn
Mar 31, 2024 -96.73 Mn
Dec 31, 2023 -95.94 Mn
Sep 30, 2023 -91.32 Mn
Jun 30, 2023 -89.99 Mn
Mar 31, 2023 -87.04 Mn
Dec 31, 2022 -97.11 Mn
Sep 30, 2022 -91.69 Mn
Jun 30, 2022 -100.26 Mn
Mar 31, 2022 -104.23 Mn
Dec 31, 2021 -98.58 Mn
Sep 30, 2021 -84.26 Mn
Jun 30, 2021 -82.79 Mn