Agios Pharmaceuticals (AGIO) EBITDA Margin (2012 - 2026)
Agios Pharmaceuticals' EBITDA Margin was -244.05% in Q2 2026, up 765.96 percentage points from -1010.01% a year earlier and up 279.72 percentage points from the prior quarter.
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Analysis
Agios Pharmaceuticals (AGIO) EBITDA Margin (2012 - 2026) Analysis & Trends
On a trailing twelve-month basis, Agios Pharmaceuticals' EBITDA Margin was -461.34% through Jun 30, 2026, up 654.95 percentage points year-over-year; for FY2025, it came in at -864.28%, up 286.69 percentage points from FY2024.
- EBITDA Margin has now increased for three consecutive years, with a three-year change of +1807.65 percentage points (FY2022 to FY2025).
- In earlier years, EBITDA Margin was -1150.98% in FY2024 (+283.85 pp), -1434.83% in FY2023 (+1237.10 pp) and -2671.93% in FY2022.
- The Q2 2026 figure marks the highest quarterly EBITDA Margin since Q4 2020.
- Compared with a year earlier, EBITDA Margin has increased for five straight quarters, with an average year-over-year change of +358.60 percentage points over the last eight quarters.
- The best year-over-year quarter for EBITDA Margin over five years was Q1 2023 (a gain of 10275.43 percentage points); the worst was Q1 2025 (a drop of 99.45 percentage points).
- Per Business Quant data, AGIO's EBITDA Margin in the three quarters before Q2 2026 was -523.77% (Q1 2026), -602.55% (Q4 2025) and -896.70% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Agios Pharmaceuticals | 1.99 Bn | 1.99 Bn | 41.75 Mn | -244.05% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -244.05% |
| Mar 31, 2026 | -523.77% |
| Dec 31, 2025 | -602.55% |
| Sep 30, 2025 | -896.70% |
| Jun 30, 2025 | -1,010.01% |
| Mar 31, 2025 | -1,207.32% |
| Dec 31, 2024 | -1,152.56% |
| Sep 30, 2024 | -1,131.93% |
| Jun 30, 2024 | -1,209.80% |
| Mar 31, 2024 | -1,107.88% |
| Dec 31, 2023 | -1,476.47% |
| Sep 30, 2023 | -1,341.72% |
| Jun 30, 2023 | -1,369.09% |
| Mar 31, 2023 | -1,583.58% |
| Dec 31, 2022 | -2,258.89% |
| Sep 30, 2022 | -2,534.39% |
| Jun 30, 2022 | -1,708.15% |
| Mar 31, 2022 | -11,859.01% |
| Dec 31, 2020 | -203.99% |
| Sep 30, 2020 | -224.67% |
API Access
Agios Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "AGIO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=AGIO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();