Agios Pharmaceuticals (AGIO) EBITDA (2012 - 2026)

Agios Pharmaceuticals (AGIO) reported EBITDA of -$110.0 million for Q1 2026, down 3.18% on a YoY basis from -$113.6 million in Q1 2025, and up 9.5% quarter-over-quarter from -$121.6 million in Q4 2025.

Agios Pharmaceuticals (AGIO) EBITDA (2012 - 2026) Analysis & Trends

Agios Pharmaceuticals has reported EBITDA for 15 years, with the latest figure at -$110.0 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 3.18% year-over-year to -$110.0 million; the trailing twelve-month figure through Mar 2026 stood at -$475.5 million (down 8.0% YoY), and the FY2025 full-year result was -$472.1 million, down 10.9% from the prior year.
  • EBITDA for Q1 2026 stood at -$110.0 million, up from -$121.6 million in the prior quarter.
  • The five-year high for EBITDA was -$90.6 million in Q1 2023, with the low at -$127.1 million in Q2 2025.
  • Historically, EBITDA has averaged -$105.2 million across 5 years, with a median of -$102.8 million in 2024.
  • Annual changes were most pronounced in 2022 — EBITDA slumped 105.4% — and 2023, when it climbed 10.41%.
  • Agios Pharmaceuticals' EBITDA stood at -$99.2 million in 2022, then dropped by 7.16% to -$106.3 million in 2023, then slipped by 17.65% to -$125.0 million in 2024, then advanced by 2.77% to -$121.6 million in 2025, then climbed by 9.5% to -$110.0 million in 2026.
  • The last three EBITDA figures came in at -$110.0 million (Q1 2026), -$121.6 million (Q4 2025), and -$116.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Agios Pharmaceuticals 2.01 Bn 2.01 Bn 19.43 Mn -110.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -110.03 Mn
Dec 31, 2025 -121.58 Mn
Sep 30, 2025 -116.87 Mn
Jun 30, 2025 -127.06 Mn
Mar 31, 2025 -106.63 Mn
Dec 31, 2024 -125.04 Mn
Sep 30, 2024 -102.81 Mn
Jun 30, 2024 -105.82 Mn
Mar 31, 2024 -92.07 Mn
Dec 31, 2023 -106.28 Mn
Sep 30, 2023 -100.90 Mn
Jun 30, 2023 -93.70 Mn
Mar 31, 2023 -90.61 Mn
Dec 31, 2022 -99.17 Mn
Sep 30, 2022 -91.09 Mn
Jun 30, 2022 -97.64 Mn
Mar 31, 2022 -101.15 Mn
Dec 31, 2021 -104.83 Mn
Sep 30, 2021 -88.82 Mn
Jun 30, 2021 -86.36 Mn