Agios Pharmaceuticals (AGIO) EBIT (2012 - 2026)

Agios Pharmaceuticals' (AGIO) quarterly EBIT came in at -$110.6 million in Q2 2026, up 12.99% YoY from -$97.8 million in Q2 2025, and little changed on a QoQ basis from -$110.0 million in Q1 2026.

Agios Pharmaceuticals (AGIO) EBIT (2012 - 2026) Analysis & Trends

Agios Pharmaceuticals (AGIO) has 15 years of EBIT data on file, last reported at -$110.6 million in Q2 2026.

  • Quarterly EBIT rose 12.99% year-over-year to -$110.6 million in Q2 2026, while the trailing twelve-month figure through Jun 2026 was -$459.0 million (up 0.54% YoY) and the FY2025 annual result came in at -$472.1 million, down 10.9% from the prior year.
  • EBIT steadied at -$110.6 million in Q2 2026, from -$110.0 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$90.6 million in Q1 2023 to a low of -$127.1 million in Q2 2025.
  • A 5-year average of -$105.5 million and a median of -$104.3 million in 2024 frame the typical range for EBIT.
  • Annual changes were most pronounced in 2025 — EBIT decreased 20.07% — and 2026, when it rose 12.99%.
  • Tracing AGIO's EBIT over 5 years: stood at -$99.2 million in 2022, then dropped by 7.16% to -$106.3 million in 2023, then slipped by 17.65% to -$125.0 million in 2024, then advanced by 2.77% to -$121.6 million in 2025, then gained by 9.07% to -$110.6 million in 2026.
  • The last three EBIT figures came in at -$110.6 million (Q2 2026), -$110.0 million (Q1 2026), and -$121.6 million (Q4 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Agios Pharmaceuticals 2.00 Bn 1.38 Bn 41.75 Mn -110.55 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -110.55 Mn
Mar 31, 2026 -110.03 Mn
Dec 31, 2025 -121.58 Mn
Sep 30, 2025 -116.87 Mn
Jun 30, 2025 -127.06 Mn
Mar 31, 2025 -106.63 Mn
Dec 31, 2024 -125.04 Mn
Sep 30, 2024 -102.81 Mn
Jun 30, 2024 -105.82 Mn
Mar 31, 2024 -92.07 Mn
Dec 31, 2023 -106.28 Mn
Sep 30, 2023 -100.90 Mn
Jun 30, 2023 -93.70 Mn
Mar 31, 2023 -90.61 Mn
Dec 31, 2022 -99.17 Mn
Sep 30, 2022 -91.09 Mn
Jun 30, 2022 -97.64 Mn
Mar 31, 2022 -101.15 Mn
Dec 31, 2021 -104.83 Mn
Sep 30, 2021 -91.15 Mn