Agenus (AGEN) EBITDA Margin (2010 - 2026)
Agenus' EBITDA Margin came in at 34.21% for Q2 2026, up 86.93 percentage points from -52.71% a year earlier but down 12.14 percentage points from the prior quarter.
Agenus (AGEN) EBITDA Margin (2010 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Agenus reported EBITDA Margin of 30.84%, up 104.04 percentage points year-over-year; for FY2025, it came in at -8.91%, up 94.64 percentage points from FY2024.
- EBITDA Margin carries a five-year change of +115.92 percentage points (FY2020 to FY2025).
- Going back by year, EBITDA Margin was -103.55% in FY2024 (-10.17 pp), -93.38% in FY2023 (+82.58 pp), -175.96% in FY2022 (-186.96 pp) and 11.00% in FY2021 (+135.83 pp).
- The five-year range for quarterly EBITDA Margin is -258.49% (Q4 2021) to 74.80% (Q3 2021).
- Year-over-year, EBITDA Margin has increased for six consecutive quarters, with an average year-over-year change of +64.57 percentage points over the last eight quarters.
- The fastest year-over-year change in EBITDA Margin over five years came in Q2 2022 (a gain of 397.83 percentage points), and the weakest in Q3 2022 (a drop of 250.19 percentage points).
- Business Quant data shows AGEN's EBITDA Margin at 46.35% (Q1 2026), 43.84% (Q4 2025) and -5.01% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Agenus | 401.87 Mn | 395.09 Mn | 34.52 Mn | 34.21% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 34.21% |
| Mar 31, 2026 | 46.35% |
| Dec 31, 2025 | 43.84% |
| Sep 30, 2025 | -5.01% |
| Jun 30, 2025 | -52.71% |
| Mar 31, 2025 | -42.00% |
| Dec 31, 2024 | -84.35% |
| Sep 30, 2024 | -112.13% |
| Jun 30, 2024 | -114.13% |
| Mar 31, 2024 | -105.37% |
| Dec 31, 2023 | 1.19% |
| Sep 30, 2023 | -178.86% |
| Jun 30, 2023 | -204.35% |
| Mar 31, 2023 | -226.09% |
| Dec 31, 2022 | -196.82% |
| Sep 30, 2022 | -175.38% |
| Jun 30, 2022 | -204.89% |
| Mar 31, 2022 | -130.30% |
| Dec 31, 2021 | -258.49% |
| Sep 30, 2021 | 74.80% |
Agenus EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=AGEN&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "AGEN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=AGEN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();