Agenus (AGEN) EBITDA Margin (2010 - 2026)
Agenus (AGEN) posted quarterly EBITDA Margin of 44.62% for Q1 2026, up 9993.0% year-over-year from N/an in Q1 2025, and up 6.01% quarter-over-quarter from 42.09% in Q4 2025.
Agenus (AGEN) EBITDA Margin (2010 - 2026) Analysis & Trends
Agenus' EBITDA Margin history runs 17 years deep, the most recent figure standing at 44.62% for Q1 2026.
- In Q1 2026, EBITDA Margin rose 9993.0% year-over-year to 44.62%; the TTM figure through Mar 2026 stood at 6.62% (up 10800.0% YoY), while the FY2025 annual figure was 17.66%, up 9878.0% from the prior year.
- EBITDA Margin for Q1 2026 stood at 44.62%, up from 42.09% in the prior quarter.
- The five-year high for EBITDA Margin was 130.27% in Q4 2022, with the low at 237.28% in Q1 2023.
- The 5-year median for EBITDA Margin is 117.41% (2024), against an average of 92.22%.
- Peak annual rise in EBITDA Margin reached 40581 bps in 2022, while the deepest fall reached 25702 bps in 2022.
- Agenus' EBITDA Margin stood at 130.27% in 2022, then plunged by 104 bps to 5.01% in 2023, then tumbled by 1825 bps to 96.49% in 2024, then jumped by 144 bps to 42.09% in 2025, then gained by 6 bps to 44.62% in 2026.
- Business Quant data shows AGEN's EBITDA Margin at 44.62% in Q1 2026, 42.09% in Q4 2025, and 15.03% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 31.68% |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 19.06% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -77,569,866.34% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 19.75% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 17.93% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -0.36% |
| 10 | Agenus | 311.95 Mn | 286.43 Mn | 34.52 Mn | 32.72% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 32.72% |
| Mar 31, 2026 | 44.62% |
| Dec 31, 2025 | 42.09% |
| Sep 30, 2025 | -15.03% |
| Jun 30, 2025 | -65.05% |
| Mar 31, 2025 | -55.31% |
| Dec 31, 2024 | -96.49% |
| Sep 30, 2024 | -125.45% |
| Jun 30, 2024 | -128.43% |
| Mar 31, 2024 | -117.41% |
| Dec 31, 2023 | -5.01% |
| Sep 30, 2023 | -190.59% |
| Jun 30, 2023 | -216.11% |
| Mar 31, 2023 | -237.28% |
| Dec 31, 2022 | 130.27% |
| Sep 30, 2022 | -182.88% |
| Jun 30, 2022 | -212.96% |
| Mar 31, 2022 | -136.70% |
| Dec 31, 2021 | -266.66% |
| Sep 30, 2021 | 74.14% |