Arcellx (ACLX) Operating Income (2021 - 2025)

Arcellx (ACLX) recorded quarterly Operating Income of $237.5 million in Q4 2025, up 484.38% quarter-over-quarter from -$61.8 million in Q3 2025, and up 546.74% on a YoY basis from $36.7 million in Q4 2024.

Arcellx (ACLX) Operating Income (2021 - 2025) Analysis & Trends

Arcellx's Operating Income history runs 5 years deep, the most recent figure standing at $237.5 million for Q4 2025.

  • In Q4 2025, Operating Income rose 546.74% year-over-year to $237.5 million; the TTM figure through Dec 2025 stood at $48.1 million (up 134.93% YoY), while the FY2025 annual figure was $48.1 million, up 134.93% from the prior year.
  • Operating Income was $237.5 million for Q4 2025 at Arcellx, up from -$61.8 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $237.5 million in Q4 2025 to a low of -$93.9 million in Q3 2022.
  • Historically, Operating Income has averaged -$21.8 million across 5 years, with a median of -$30.9 million in 2022.
  • The sharpest annual moves came in 2024 and 2025: Operating Income sank 454.37% in 2024, then surged 546.74% in 2025.
  • A 5-year view of Operating Income shows it stood at -$20.7 million in 2021, then sank by 93.27% to -$40.0 million in 2022, then surged by 137.49% to $15.0 million in 2023, then tumbled by 454.37% to -$53.2 million in 2024, then soared by 546.74% to $237.5 million in 2025.
  • The last three Operating Income figures came in at $237.5 million (Q4 2025), -$61.8 million (Q3 2025), and -$58.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Arcellx 6.48 Bn 6.48 Bn - 237.45 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 237.45 Mn
Sep 30, 2025 -61.78 Mn
Jun 30, 2025 -58.73 Mn
Mar 31, 2025 -68.90 Mn
Dec 31, 2024 -53.15 Mn
Sep 30, 2024 -33.62 Mn
Jun 30, 2024 -34.99 Mn
Mar 31, 2024 -15.81 Mn
Dec 31, 2023 15.00 Mn
Sep 30, 2023 -44.86 Mn
Jun 30, 2023 -29.56 Mn
Mar 31, 2023 -30.46 Mn
Dec 31, 2022 -40.00 Mn
Sep 30, 2022 -93.88 Mn
Jun 30, 2022 -31.29 Mn
Mar 31, 2022 -26.09 Mn
Dec 31, 2021 -20.70 Mn
Sep 30, 2021 -17.11 Mn
Jun 30, 2021 -15.93 Mn
Mar 31, 2021 -11.28 Mn