As of May 14, 2026, the three largest insider holders of ACLX are Peter W. Sonsini (TenPercentOwner, 4.75Mn shares), Peter W. Sonsini (TenPercentOwner, 4.75Mn shares), Mohamad Makhzoumi (TenPercentOwner, 4.75Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Peter W. Sonsini | - | 0 | 4,746,083 | 22 Dec, 2022 |
| Peter W. Sonsini | - | 0 | 4,746,083 | 22 Dec, 2022 |
| Mohamad Makhzoumi | - | 283 | 4,745,262 | 22 Dec, 2022 |
| Enterprise Associates 15, L.P. New | - | 4,745,262 | 0 | 22 Dec, 2022 |
| Enterprise Associates 15, L.P. New | - | 4,745,262 | 0 | 22 Dec, 2022 |
| Partners 15, L.P. Nea | - | 0 | 4,745,262 | 22 Dec, 2022 |
| Partners 15, L.P. Nea | - | 0 | 4,745,262 | 22 Dec, 2022 |
| One Capital Management, Llc Sr | - | 0 | 4,487,174 | 15 May, 2023 |
| One Capital Management, Llc Sr | - | 0 | 4,487,174 | 15 May, 2023 |
| Holdings A/S Novo | - | 4,016,878 | 0 | 09 Feb, 2022 |
| Holdings A/S Novo | - | 4,016,878 | 0 | 09 Feb, 2022 |
| Jill Carroll | - | 0 | 2,828,394 | 15 May, 2023 |
| Jill Carroll | - | 0 | 2,828,394 | 15 May, 2023 |
| Lewis T Williams | - | 0 | 2,095,114 | 09 Feb, 2022 |
| Lewis T Williams | - | 0 | 2,095,114 | 09 Feb, 2022 |
| One Capital Management, Llc Sr | - | 0 | 2,033,196 | 10 Feb, 2022 |
| Jill Carroll | - | 0 | 2,033,196 | 09 Feb, 2022 |
| One Capital Management, Llc Sr | - | 0 | 2,033,196 | 10 Feb, 2022 |
| Jill Carroll | - | 0 | 2,033,196 | 09 Feb, 2022 |
| Jill Carroll | - | 0 | 1,479,148 | 25 Mar, 2024 |
| Jill Carroll | - | 0 | 1,479,148 | 25 Mar, 2024 |
| Rami Elghandour | - | 174,887 | 0 | 04 Mar, 2026 |
| Rami Elghandour | - | 174,887 | 0 | 04 Mar, 2026 |
| Michelle Gilson | Chief Financial Officer | 67,048 | 0 | 17 Apr, 2026 |
| Michelle Gilson | Chief Financial Officer | 28,938 | 0 | 19 Mar, 2026 |
| Christopher Heery | Chief Medical Officer | 23,749 | 0 | 14 Jan, 2026 |
| Christopher Heery | Chief Medical Officer | 23,749 | 0 | 14 Jan, 2026 |
| Scott D Sandell | - | 0 | 1,622 | 22 Dec, 2022 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 15 Apr, 2026 | Michelle Gilson | Common Stock | A | 36,000 | $8.66 | 64,938 | D | M |
| 16 Apr, 2026 | Michelle Gilson | Common Stock | A | 2,110 | $8.66 | 67,048 | D | M |
| 15 Apr, 2026 | Michelle Gilson | Stock Option (right to buy) | D | 36,000 | $0.00 | 42,315 | D | M |
| 16 Apr, 2026 | Michelle Gilson | Stock Option (right to buy) | D | 2,110 | $0.00 | 40,205 | D | M |
| 17 Mar, 2026 | Michelle Gilson | Common Stock | D | 5,000 | $0.00 | 28,938 | D | G |
| 17 Mar, 2026 | Michelle Gilson | Common Stock | D | 5,000 | $0.00 | 28,938 | D | G |
| 04 Mar, 2026 | Rami Elghandour | Common Stock | D | 101,164 | $0.00 | 174,887 | D | G |
| 04 Mar, 2026 | Rami Elghandour | Common Stock | D | 101,164 | $0.00 | 174,887 | D | G |
| 02 Jan, 2026 | Rami Elghandour | Common Stock | A | 55,459 | $0.00 | 673,378 | D | M |
| 02 Jan, 2026 | Rami Elghandour | Common Stock | A | 55,459 | $0.00 | 673,378 | D | M |
| 03 Jan, 2026 | Rami Elghandour | Common Stock | A | 53,098 | $0.00 | 726,476 | D | M |
| 03 Jan, 2026 | Rami Elghandour | Common Stock | A | 53,098 | $0.00 | 726,476 | D | M |
| 06 Jan, 2026 | Rami Elghandour | Common Stock | A | 55,991 | $0.00 | 782,467 | D | M |
| 06 Jan, 2026 | Rami Elghandour | Common Stock | A | 55,991 | $0.00 | 782,467 | D | M |
| 27 Feb, 2026 | Rami Elghandour | Common Stock | D | 89,916 | $113.92 | 276,051 | D | S |
| 27 Feb, 2026 | Rami Elghandour | Common Stock | D | 89,916 | $113.92 | 276,051 | D | S |
| 06 Jan, 2026 | Michelle Gilson | Common Stock | A | 20,530 | $0.00 | 64,832 | D | M |
| 06 Jan, 2026 | Michelle Gilson | Common Stock | A | 20,530 | $0.00 | 64,832 | D | M |
| 25 Feb, 2026 | Michelle Gilson | Common Stock | D | 11,219 | $113.82 | 33,938 | D | S |
| 25 Feb, 2026 | Michelle Gilson | Common Stock | D | 11,219 | $113.82 | 33,938 | D | S |