Arcellx (ACLX) EBITDA (2021 - 2025)

Arcellx (ACLX) recorded quarterly EBITDA of -$58.0 million in Q4 2025, down 4.5% quarter-over-quarter from -$55.5 million in Q3 2025, and down 20.45% on a YoY basis from -$72.9 million in Q4 2024.

Arcellx (ACLX) EBITDA (2021 - 2025) Analysis & Trends

Arcellx's EBITDA history runs 5 years deep, the most recent figure standing at -$58.0 million for Q4 2025.

  • In Q4 2025, EBITDA fell 20.45% year-over-year to -$58.0 million; the TTM figure through Dec 2025 stood at -$228.9 million (down 113.87% YoY), while the FY2025 annual figure was -$228.9 million, down 113.87% from the prior year.
  • EBITDA was -$58.0 million for Q4 2025 at Arcellx, down from -$55.5 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $20.5 million in Q4 2023 to a low of -$93.0 million in Q3 2022.
  • Historically, EBITDA has averaged -$33.0 million across 5 years, with a median of -$27.3 million in 2023.
  • The sharpest annual moves came in 2023 and 2025: EBITDA soared 152.7% in 2023, then tumbled 656.56% in 2025.
  • A 5-year view of EBITDA shows it stood at -$20.7 million in 2021, then tumbled by 87.64% to -$38.8 million in 2022, then soared by 152.7% to $20.5 million in 2023, then sank by 335.3% to -$48.1 million in 2024, then retreated by 20.45% to -$58.0 million in 2025.
  • The last three EBITDA figures came in at -$58.0 million (Q4 2025), -$55.5 million (Q3 2025), and -$53.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Arcellx 6.48 Bn 6.48 Bn - -57.98 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -57.98 Mn
Sep 30, 2025 -55.48 Mn
Jun 30, 2025 -53.02 Mn
Mar 31, 2025 -62.47 Mn
Dec 31, 2024 -48.13 Mn
Sep 30, 2024 -23.18 Mn
Jun 30, 2024 -27.48 Mn
Mar 31, 2024 -8.26 Mn
Dec 31, 2023 20.46 Mn
Sep 30, 2023 -39.39 Mn
Jun 30, 2023 -23.95 Mn
Mar 31, 2023 -27.04 Mn
Dec 31, 2022 -38.81 Mn
Sep 30, 2022 -93.01 Mn
Jun 30, 2022 -30.99 Mn
Mar 31, 2022 -26.07 Mn
Dec 31, 2021 -20.69 Mn
Sep 30, 2021 -17.10 Mn
Jun 30, 2021 -15.93 Mn
Mar 31, 2021 -11.28 Mn