Arcellx (ACLX) EBITDA (2021 - 2025)

Arcellx's quarterly EBITDA came in at -$58.0 million in Q4 2025, down 20.45% year-on-year from -$72.9 million in Q4 2024, and down 4.5% quarter-over-quarter from -$55.5 million in Q3 2025.

Arcellx has reported EBITDA for 5 years, with the latest figure at -$58.0 million in Q4 2025.

  • For the quarter ending Q4 2025, EBITDA fell 20.45% year-over-year to -$58.0 million; the trailing twelve-month figure through Dec 2025 stood at -$228.9 million (down 113.87% YoY), and the FY2025 full-year result was -$228.9 million, down 113.87% from the prior year.
  • EBITDA for Q4 2025 stood at -$58.0 million, down from -$55.5 million in the prior quarter.
  • The five-year high for EBITDA was $20.5 million in Q4 2023, with the low at -$93.0 million in Q3 2022.
  • Average EBITDA over 5 years is -$33.0 million, with a median of -$27.3 million recorded in 2023.
  • Year-over-year, EBITDA surged 152.7% in 2023 and tumbled 656.56% in 2025.
  • Tracing ACLX's EBITDA over 5 years: stood at -$20.7 million in 2021, then slumped by 87.64% to -$38.8 million in 2022, then jumped by 152.7% to $20.5 million in 2023, then plunged by 335.3% to -$48.1 million in 2024, then decreased by 20.45% to -$58.0 million in 2025.
  • The last three EBITDA figures came in at -$58.0 million (Q4 2025), -$55.5 million (Q3 2025), and -$53.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Arcellx 6.48 Bn 6.48 Bn - -57.98 Mn

Historic Data

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DateValue
Dec 31, 2025 -57.98 Mn
Sep 30, 2025 -55.48 Mn
Jun 30, 2025 -53.02 Mn
Mar 31, 2025 -62.47 Mn
Dec 31, 2024 -48.13 Mn
Sep 30, 2024 -23.18 Mn
Jun 30, 2024 -27.48 Mn
Mar 31, 2024 -8.26 Mn
Dec 31, 2023 20.46 Mn
Sep 30, 2023 -39.39 Mn
Jun 30, 2023 -23.95 Mn
Mar 31, 2023 -27.04 Mn
Dec 31, 2022 -38.81 Mn
Sep 30, 2022 -93.01 Mn
Jun 30, 2022 -30.99 Mn
Mar 31, 2022 -26.07 Mn
Dec 31, 2021 -20.69 Mn
Sep 30, 2021 -17.10 Mn
Jun 30, 2021 -15.93 Mn
Mar 31, 2021 -11.28 Mn