AC Immune (ACIU) Free Cash Flow (2015 - 2025)

AC Immune's (ACIU) quarterly Free Cash Flow came in at -$20.8 million in Q4 2025, down 402.45% year-on-year from $6.9 million in Q4 2024, and up 10.66% on a QoQ basis from -$23.3 million in Q3 2025.

AC Immune (ACIU) Free Cash Flow (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has 11 years of Free Cash Flow data on file, last reported at -$20.8 million in Q4 2025.

  • On a quarterly basis, Free Cash Flow fell 402.45% year-over-year to -$20.8 million in Q4 2025; TTM through Mar 2026 was -$63.2 million, a 225.27% decrease from a year earlier, with the FY2025 full-year figure at -$84.5 million, down 211.47% from the prior year.
  • Free Cash Flow for Q4 2025 stood at -$20.8 million, up from -$23.3 million in the prior quarter.
  • Over the last five years, Free Cash Flow for ACIU reached as high as $80.8 million in Q2 2024 and fell as low as -$24.6 million in Q4 2021.
  • Historically, Free Cash Flow has averaged -$11.5 million across 5 years, with a median of -$18.1 million in 2023.
  • Across the five-year window, Free Cash Flow jumped 617.89% in 2024 and plunged 1548.68% in 2025, its largest moves.
  • Year by year, Free Cash Flow stood at -$24.6 million in 2021, then advanced by 16.54% to -$20.6 million in 2022, then increased by 11.15% to -$18.3 million in 2023, then jumped by 137.64% to $6.9 million in 2024, then plunged by 402.45% to -$20.8 million in 2025.
  • Per Business Quant data, the three most recent Free Cash Flow figures were -$20.8 million in Q4 2025, -$23.3 million in Q3 2025, and -$19.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -19.58 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.49 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 158.09 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -354.95 Mn
10 AC Immune 222.66 Mn 222.66 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -20.80 Mn
Dec 31, 2025 -20.80 Mn
Sep 30, 2025 -23.28 Mn
Sep 30, 2025 -23.28 Mn
Jun 30, 2025 -19.12 Mn
Jun 30, 2025 -19.12 Mn
Mar 31, 2025 -21.13 Mn
Mar 31, 2025 -21.13 Mn
Dec 31, 2024 6.88 Mn
Dec 31, 2024 6.88 Mn
Sep 30, 2024 -16.13 Mn
Sep 30, 2024 -16.13 Mn
Jun 30, 2024 80.83 Mn
Jun 30, 2024 80.83 Mn
Mar 31, 2024 1.46 Mn
Mar 31, 2024 1.46 Mn
Dec 31, 2023 -18.27 Mn
Dec 31, 2023 -18.27 Mn
Sep 30, 2023 -14.93 Mn
Sep 30, 2023 -14.93 Mn