AC Immune ACIU
NASDAQ ACIU
$2.86 -0.07 (-2.39%)
At close: Sep 4, 2026 · 4:00 PM EDT

AC Immune (ACIU) Free Cash Flow (2015 - 2025)

AC Immune (ACIU) posted quarterly Free Cash Flow of -$20.8 million for Q4 2025, down 402.45% year-over-year from $6.9 million in Q4 2024, and up 10.66% quarter-over-quarter from -$23.3 million in Q3 2025.

Analysis

AC Immune (ACIU) Free Cash Flow (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has reported Free Cash Flow for 11 consecutive years, with -$20.8 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Free Cash Flow fell 402.45% year-over-year to -$20.8 million; the TTM figure through Mar 2026 stood at -$63.2 million (down 225.27% YoY), while the FY2025 annual figure was -$84.5 million, down 211.47% from the prior year.
  • Free Cash Flow improved to -$20.8 million in Q4 2025 per ACIU's latest filing, from -$23.3 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $80.8 million in Q2 2024 and bottomed at -$24.5 million in Q1 2022.
  • Historically, Free Cash Flow has averaged -$11.6 million across 5 years, with a median of -$18.1 million in 2023.
  • Annual changes were most pronounced in 2024 — Free Cash Flow soared 617.89% — and 2025, when it slumped 1548.68%.
  • AC Immune's Free Cash Flow stood at -$24.3 million in 2021, then increased by 15.12% to -$20.6 million in 2022, then climbed by 11.32% to -$18.3 million in 2023, then surged by 137.64% to $6.9 million in 2024, then plunged by 402.45% to -$20.8 million in 2025.
  • Business Quant data shows ACIU's Free Cash Flow at -$20.8 million in Q4 2025, -$23.3 million in Q3 2025, and -$19.1 million in Q2 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -563.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -389.61 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 437.80 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 292.04 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 477.44 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -95.09 Mn
10 AC Immune 285.13 Mn 285.13 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 -20.80 Mn
Sep 30, 2025 -23.28 Mn
Jun 30, 2025 -19.12 Mn
Mar 31, 2025 -21.13 Mn
Dec 31, 2024 6.88 Mn
Sep 30, 2024 -16.13 Mn
Jun 30, 2024 80.83 Mn
Mar 31, 2024 1.46 Mn
Dec 31, 2023 -18.27 Mn
Sep 30, 2023 -14.93 Mn
Jun 30, 2023 -15.61 Mn
Mar 31, 2023 -17.95 Mn
Dec 31, 2022 -18.03 Mn
Sep 30, 2022 -13.89 Mn
Jun 30, 2022 -19.67 Mn
Mar 31, 2022 -24.47 Mn
Dec 31, 2021 -18.55 Mn
Sep 30, 2021 -15.25 Mn
Jun 30, 2021 -16.88 Mn
Mar 31, 2021 -18.30 Mn