AC Immune (ACIU) Free Cash Flow (2015 - 2025)
AC Immune (ACIU) reported Free Cash Flow of -$20.8 million for Q4 2025, down 402.45% year-over-year from $6.9 million in Q4 2024, and up 10.66% on a QoQ basis from -$23.3 million in Q3 2025.
AC Immune (ACIU) has 11 years of Free Cash Flow data on file, last reported at -$20.8 million in Q4 2025.
- Quarterly Free Cash Flow fell 402.45% year-over-year to -$20.8 million in Q4 2025, while the trailing twelve-month figure through Mar 2026 was -$63.2 million (down 225.27% YoY) and the FY2025 annual result came in at -$84.5 million, down 211.47% from the prior year.
- Free Cash Flow advanced to -$20.8 million in Q4 2025 per ACIU's latest filing, from -$23.3 million in the prior quarter.
- Across five years, Free Cash Flow topped out at $80.8 million in Q2 2024 and bottomed at -$24.5 million in Q1 2022.
- The 5-year median for Free Cash Flow is -$18.1 million (2023), against an average of -$11.5 million.
- The widest annual swing landed in 2024, when Free Cash Flow jumped 617.89%; it then plunged 1548.68% in 2025.
- Tracing ACIU's Free Cash Flow over 5 years: stood at -$23.8 million in 2021, then advanced by 15.07% to -$20.2 million in 2022, then climbed by 9.45% to -$18.3 million in 2023, then surged by 137.64% to $6.9 million in 2024, then sank by 402.45% to -$20.8 million in 2025.
- Per Business Quant, the three latest ACIU Free Cash Flow figures stand at -$20.8 million (Q4 2025), -$23.3 million (Q3 2025), and -$19.1 million (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -1.67 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -12.20 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.49 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.29 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 848.30 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 48.67 Mn |
| 10 | AC Immune | 325.88 Mn | 211.53 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -20.80 Mn |
| Dec 31, 2025 | -20.80 Mn |
| Sep 30, 2025 | -23.28 Mn |
| Sep 30, 2025 | -23.28 Mn |
| Jun 30, 2025 | -19.12 Mn |
| Jun 30, 2025 | -19.12 Mn |
| Mar 31, 2025 | -21.13 Mn |
| Mar 31, 2025 | -21.13 Mn |
| Dec 31, 2024 | 6.88 Mn |
| Dec 31, 2024 | 6.88 Mn |
| Sep 30, 2024 | -16.13 Mn |
| Sep 30, 2024 | -16.13 Mn |
| Jun 30, 2024 | 80.83 Mn |
| Jun 30, 2024 | 80.83 Mn |
| Mar 31, 2024 | 1.46 Mn |
| Mar 31, 2024 | 1.46 Mn |
| Dec 31, 2023 | -18.27 Mn |
| Dec 31, 2023 | -18.27 Mn |
| Sep 30, 2023 | -14.93 Mn |
| Sep 30, 2023 | -14.93 Mn |
| Jun 30, 2023 | -15.61 Mn |
| Jun 30, 2023 | -15.61 Mn |
| Mar 31, 2023 | -17.95 Mn |
| Mar 31, 2023 | -17.95 Mn |
| Dec 31, 2022 | -20.17 Mn |
| Dec 31, 2022 | -20.17 Mn |
| Sep 30, 2022 | -13.89 Mn |
| Sep 30, 2022 | -13.89 Mn |
| Jun 30, 2022 | -19.67 Mn |
| Jun 30, 2022 | -19.67 Mn |
| Mar 31, 2022 | -24.47 Mn |
| Mar 31, 2022 | -24.47 Mn |
| Dec 31, 2021 | -23.75 Mn |
| Dec 31, 2021 | -23.75 Mn |
| Sep 30, 2021 | -15.25 Mn |
| Sep 30, 2021 | -15.25 Mn |
| Jun 30, 2021 | -16.88 Mn |
| Jun 30, 2021 | -16.88 Mn |
| Mar 31, 2021 | -18.30 Mn |
| Mar 31, 2021 | -18.30 Mn |
| Dec 31, 2020 | -23.93 Mn |
| Dec 31, 2020 | -23.93 Mn |
| Sep 30, 2020 | -16.67 Mn |
| Sep 30, 2020 | -16.67 Mn |
| Jun 30, 2020 | -15.04 Mn |
| Jun 30, 2020 | -15.04 Mn |
| Mar 31, 2020 | -9.80 Mn |
| Mar 31, 2020 | -9.80 Mn |
| Dec 31, 2019 | -9.64 Mn |
| Dec 31, 2019 | -9.64 Mn |
| Sep 30, 2019 | 16.81 Mn |
| Sep 30, 2019 | 16.81 Mn |
| Jun 30, 2019 | -16.35 Mn |
| Jun 30, 2019 | -16.35 Mn |
| Mar 31, 2019 | 66.77 Mn |
| Mar 31, 2019 | 66.77 Mn |
| Dec 31, 2018 | -15.01 Mn |
| Dec 31, 2018 | -15.01 Mn |
| Sep 30, 2018 | -11.89 Mn |
| Sep 30, 2018 | -11.89 Mn |
| Jun 30, 2018 | -6.83 Mn |
| Jun 30, 2018 | -6.83 Mn |
| Mar 31, 2018 | -12.94 Mn |
| Mar 31, 2018 | -12.94 Mn |
| Dec 31, 2017 | 27.00 Bn |
| Dec 31, 2017 | 27.00 Bn |
| Sep 30, 2017 | -27.69 Bn |
| Sep 30, 2017 | -27.69 Bn |
| Jun 30, 2017 | -8.22 Mn |
| Jun 30, 2017 | -8.22 Mn |
| Mar 31, 2017 | -11.25 Mn |
| Mar 31, 2017 | -11.25 Mn |
| Dec 31, 2016 | -8.52 Mn |
| Dec 31, 2016 | -8.52 Mn |
| Sep 30, 2016 | 9.09 Mn |
| Sep 30, 2016 | 9.09 Mn |
| Jun 30, 2016 | 597,770.12 |
| Jun 30, 2016 | 597,770.12 |
| Mar 31, 2016 | -7.53 Mn |
| Mar 31, 2016 | -7.53 Mn |
| Dec 31, 2015 | -6.12 Mn |
| Dec 31, 2015 | -6.12 Mn |