AC Immune (ACIU) Free Cash Flow (2015 - 2025)
AC Immune (ACIU) posted quarterly Free Cash Flow of -$20.8 million for Q4 2025, down 402.45% year-over-year from $6.9 million in Q4 2024, and up 10.66% quarter-over-quarter from -$23.3 million in Q3 2025.
AC Immune (ACIU) Free Cash Flow (2015 - 2025) Analysis & Trends
AC Immune (ACIU) has reported Free Cash Flow for 11 consecutive years, with -$20.8 million the latest figure, recorded in Q4 2025.
- In Q4 2025, Free Cash Flow fell 402.45% year-over-year to -$20.8 million; the TTM figure through Mar 2026 stood at -$63.2 million (down 225.27% YoY), while the FY2025 annual figure was -$84.5 million, down 211.47% from the prior year.
- Free Cash Flow improved to -$20.8 million in Q4 2025 per ACIU's latest filing, from -$23.3 million in the prior quarter.
- Across five years, Free Cash Flow topped out at $80.8 million in Q2 2024 and bottomed at -$24.5 million in Q1 2022.
- Historically, Free Cash Flow has averaged -$11.6 million across 5 years, with a median of -$18.1 million in 2023.
- Annual changes were most pronounced in 2024 — Free Cash Flow soared 617.89% — and 2025, when it slumped 1548.68%.
- AC Immune's Free Cash Flow stood at -$24.3 million in 2021, then increased by 15.12% to -$20.6 million in 2022, then climbed by 11.32% to -$18.3 million in 2023, then surged by 137.64% to $6.9 million in 2024, then plunged by 402.45% to -$20.8 million in 2025.
- Business Quant data shows ACIU's Free Cash Flow at -$20.8 million in Q4 2025, -$23.3 million in Q3 2025, and -$19.1 million in Q2 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.01 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 572.80 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -389.61 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 437.80 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2.33 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 477.44 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 292.04 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -95.09 Mn |
| 10 | AC Immune | 253.89 Mn | 253.89 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -20.80 Mn |
| Dec 31, 2025 | -20.80 Mn |
| Sep 30, 2025 | -23.28 Mn |
| Sep 30, 2025 | -23.28 Mn |
| Jun 30, 2025 | -19.12 Mn |
| Jun 30, 2025 | -19.12 Mn |
| Mar 31, 2025 | -21.13 Mn |
| Mar 31, 2025 | -21.13 Mn |
| Dec 31, 2024 | 6.88 Mn |
| Dec 31, 2024 | 6.88 Mn |
| Sep 30, 2024 | -16.13 Mn |
| Sep 30, 2024 | -16.13 Mn |
| Jun 30, 2024 | 80.83 Mn |
| Jun 30, 2024 | 80.83 Mn |
| Mar 31, 2024 | 1.46 Mn |
| Mar 31, 2024 | 1.46 Mn |
| Dec 31, 2023 | -18.27 Mn |
| Dec 31, 2023 | -18.27 Mn |
| Sep 30, 2023 | -14.93 Mn |
| Sep 30, 2023 | -14.93 Mn |