AC Immune (ACIU) FCF Margin (2015 - 2025)

AC Immune's (ACIU) quarterly FCF Margin came in at 4918.05% in Q4 2025, down 544786.0% year-on-year from N/an in Q4 2024, and down 147.99% on a QoQ basis from 1983.17% in Q3 2025.

AC Immune (ACIU) FCF Margin (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has 9 years of FCF Margin data on file, last reported at 4918.05% in Q4 2025.

  • On a quarterly basis, FCF Margin fell 544786.0% year-over-year to 4918.05% in Q4 2025; TTM through Mar 2026 was 1372.9%, a 152777.0% decrease from a year earlier, with the FY2025 full-year figure at 1961.1%, down 220431.0% from the prior year.
  • FCF Margin for Q4 2025 stood at 4918.05%, down from 1983.17% in the prior quarter.
  • Over the last five years, FCF Margin for ACIU reached as high as 10639.74% in Q2 2024 and fell as low as 4918.05% in Q4 2025.
  • Historically, FCF Margin has averaged 92.48% across 3 years, with a median of 777.42% in 2022.
  • On a YoY basis, FCF Margin climbed as much as 192834 bps in 2025 and fell as far as 1185176 bps in 2025.
  • Year by year, FCF Margin stood at 342.82% in 2022, then surged by 255 bps to 529.82% in 2024, then plunged by 1028 bps to 4918.05% in 2025.
  • Per Business Quant data, the three most recent FCF Margin figures were 4918.05% in Q4 2025, 1983.17% in Q3 2025, and 1212.02% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 10.45%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 43.35%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 23.53%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 AC Immune 222.66 Mn 222.66 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -4,918.05%
Sep 30, 2025 -1,983.17%
Jun 30, 2025 -1,212.02%
Mar 31, 2025 -1,918.79%
Dec 31, 2024 529.82%
Sep 30, 2024 -54.83%
Jun 30, 2024 10,639.74%
Sep 30, 2022 -342.82%
Dec 31, 2020 -2,308.58%
Sep 30, 2020 -1,359.57%
Jun 30, 2020 -1,333.43%
Mar 31, 2020 -76.96%
Dec 31, 2019 -1,109.88%
Sep 30, 2019 752.64%
Jun 30, 2019 -1,085.11%
Mar 31, 2019 88.61%
Dec 31, 2018 -1,332.11%
Sep 30, 2018 -507.68%
Jun 30, 2018 -331.56%
Mar 31, 2018 -841.63%