AC Immune (ACIU) FCF Margin (2015 - 2025)

AC Immune (ACIU) posted quarterly FCF Margin of 4918.05% for Q4 2025, down 544786.0% year-over-year from N/an in Q4 2024, and down 147.99% quarter-over-quarter from 1983.17% in Q3 2025.

AC Immune (ACIU) FCF Margin (2015 - 2025) Analysis & Trends

AC Immune (ACIU) has reported FCF Margin for 9 consecutive years, with 4918.05% the latest figure, recorded in Q4 2025.

  • In Q4 2025, FCF Margin fell 544786.0% year-over-year to 4918.05%; the TTM figure through Mar 2026 stood at 1372.9% (down 152777.0% YoY), while the FY2025 annual figure was 1961.1%, down 220431.0% from the prior year.
  • FCF Margin declined to 4918.05% in Q4 2025 per ACIU's latest filing, from 1983.17% in the prior quarter.
  • Across five years, FCF Margin topped out at 10639.74% in Q2 2024 and bottomed at 56697.14% in Q4 2022.
  • Historically, FCF Margin has averaged 6217.61% across 3 years, with a median of 1212.02% in 2025.
  • On a YoY basis, FCF Margin climbed as much as 192834 bps in 2025 and fell as far as 1185176 bps in 2025.
  • AC Immune's FCF Margin stood at 56697.14% in 2022, then surged by 101 bps to 529.82% in 2024, then plunged by 1028 bps to 4918.05% in 2025.
  • Business Quant data shows ACIU's FCF Margin at 4918.05% in Q4 2025, 1983.17% in Q3 2025, and 1212.02% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 13.35%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 25.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,594.17%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 70.82%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 22.62%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -22.35%
10 AC Immune 253.89 Mn 253.89 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -4,918.05%
Sep 30, 2025 -1,983.17%
Jun 30, 2025 -1,212.02%
Mar 31, 2025 -1,918.79%
Dec 31, 2024 529.82%
Sep 30, 2024 -54.83%
Jun 30, 2024 10,639.74%
Dec 31, 2022 -56,697.14%
Sep 30, 2022 -344.00%
Dec 31, 2020 -2,320.55%
Sep 30, 2020 -1,366.61%
Jun 30, 2020 -1,338.41%
Mar 31, 2020 -77.15%
Dec 31, 2019 -1,109.88%
Sep 30, 2019 752.64%
Jun 30, 2019 -1,085.11%
Mar 31, 2019 88.61%
Dec 31, 2018 -1,359.41%
Sep 30, 2018 -507.68%
Jun 30, 2018 -331.56%